SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
LEU A 371
LEU A 369
LEU A 349
CU  A 555 ( 3.2A)
None
None
None
1.24A 1a4lD-1asoA:
undetectable
1a4lD-1asoA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 506
HIS A 104
HIS A  60
HIS A 450
CU  A 555 (-3.1A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
0.93A 1e9yB-1asoA:
undetectable
1e9yB-1asoA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.36A 1fkfA-1asoA:
undetectable
1fkfA-1asoA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.35A 1fkjA-1asoA:
undetectable
1fkjA-1asoA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 PRO A 372
ASP A 389
ASN A 391
TYR A 376
None
1.31A 1hpkA-1asoA:
0.0
1hpkA-1asoA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 TRP A  71
TYR A  91
GLY A 378
LEU A 377
PRO A 532
NAG  A 553 (-4.6A)
None
None
None
NAG  A 553 (-4.3A)
1.45A 1i9jH-1asoA:
undetectable
1i9jL-1asoA:
undetectable
1i9jH-1asoA:
15.62
1i9jL-1asoA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.53A 1oe1A-1asoA:
17.8
1oe1A-1asoA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.53A 1oe2A-1asoA:
18.0
1oe2A-1asoA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.57A 1oe3A-1asoA:
18.0
1oe3A-1asoA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 ALA A  72
SER A  79
PHE A  93
ILE A  59
None
1.01A 1yc2A-1asoA:
undetectable
1yc2A-1asoA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 SER A 220
ASP A 255
ARG A 322
ASP A 319
None
1.44A 2bm9C-1asoA:
0.0
2bm9C-1asoA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.34A 2fkeA-1asoA:
undetectable
2fkeA-1asoA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.28A 2fqdA-1asoA:
29.0
2fqdA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.26A 2fqeA-1asoA:
28.9
2fqeA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.25A 2fqeA-1asoA:
29.0
2fqeA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.88A 2fqeA-1asoA:
29.0
2fqeA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.22A 2fqfA-1asoA:
28.9
2fqfA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.19A 2fqfA-1asoA:
28.9
2fqfA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.35A 2fqfA-1asoA:
28.9
2fqfA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.84A 2fqfA-1asoA:
28.9
2fqfA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.23A 2fqgA-1asoA:
29.0
2fqgA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 2fqgA-1asoA:
29.0
2fqgA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.85A 2fqgA-1asoA:
29.0
2fqgA-1asoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 LEU A 513
HIS A 448
HIS A 506
HIS A 508
None
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 556 (-3.3A)
1.22A 2oqeE-1asoA:
0.0
2oqeE-1asoA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 PRO A 478
PRO A 477
GLY A 458
THR A 491
VAL A 483
None
1.30A 2uvnB-1asoA:
0.0
2uvnB-1asoA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A 106
HIS A 104
HIS A 450
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 556 (-3.1A)
CU  A 555 ( 3.2A)
0.87A 2wkoA-1asoA:
undetectable
2wkoA-1asoA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A 106
HIS A 104
HIS A 450
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 556 (-3.1A)
CU  A 555 ( 3.2A)
0.95A 2wkoF-1asoA:
undetectable
2wkoF-1asoA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.50A 2xxgA-1asoA:
18.0
2xxgA-1asoA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.53A 2xxgC-1asoA:
18.0
2xxgC-1asoA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 SER A 442
GLY A 460
GLU A 467
GLU A 468
None
1.15A 3k9fA-1asoA:
0.0
3k9fB-1asoA:
0.0
3k9fD-1asoA:
undetectable
3k9fA-1asoA:
20.69
3k9fB-1asoA:
20.69
3k9fD-1asoA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 LEU A 371
HIS A 506
HIS A 450
HIS A 106
None
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.3A)
0.99A 3kecA-1asoA:
undetectable
3kecA-1asoA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
3 / 3 HIS A 506
HIS A 448
HIS A 450
CU  A 555 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.81A 3mihA-1asoA:
0.0
3mihA-1asoA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.32A 3qpkA-1asoA:
38.6
3qpkA-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
3 / 3 HIS A 106
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.17A 3qpkA-1asoA:
38.6
3qpkA-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.16A 3qpkA-1asoA:
38.6
3qpkA-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.33A 3qpkA-1asoA:
38.6
3qpkA-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.87A 3qpkA-1asoA:
38.6
3qpkA-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.31A 3qpkB-1asoA:
38.5
3qpkB-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
3 / 3 HIS A 106
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.18A 3qpkB-1asoA:
38.5
3qpkB-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.15A 3qpkB-1asoA:
38.5
3qpkB-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.28A 3qpkB-1asoA:
38.5
3qpkB-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.86A 3qpkB-1asoA:
38.5
3qpkB-1asoA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 ALA A 225
ILE A 170
LEU A 227
GLU A 166
ALA A 284
None
1.14A 3r9sA-1asoA:
undetectable
3r9sA-1asoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_H_LFXH101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 SER A 442
GLY A 460
GLU A 467
GLU A 468
None
1.27A 3raeB-1asoA:
undetectable
3raeD-1asoA:
undetectable
3raeB-1asoA:
20.69
3raeD-1asoA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 8 PRO A 291
TRP A 277
SER A 181
ILE A 182
None
0.97A 3sfeB-1asoA:
0.0
3sfeC-1asoA:
undetectable
3sfeB-1asoA:
16.61
3sfeC-1asoA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 10 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.32A 3uf8A-1asoA:
undetectable
3uf8A-1asoA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.37A 3vawA-1asoA:
undetectable
3vawA-1asoA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 GLY A 524
TRP A 503
ALA A 522
PHE A 495
None
1.47A 3wqwA-1asoA:
0.0
3wqwA-1asoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
HIS A 512
MET A 517
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 (-3.1A)
CU  A 554 (-2.9A)
0.19A 4ef3A-1asoA:
28.8
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  62
HIS A 104
HIS A 448
HIS A 508
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
0.26A 4ef3A-1asoA:
28.9
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 506
HIS A  60
HIS A 106
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
0.65A 4ef3A-1asoA:
28.9
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A  60
HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.29A 4ef3A-1asoA:
28.9
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 448
HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.66A 4ef3A-1asoA:
28.9
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.21A 4ef3A-1asoA:
28.9
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.86A 4ef3A-1asoA:
28.9
4ef3A-1asoA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 506
HIS A 104
HIS A  60
HIS A 450
CU  A 555 (-3.1A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
0.93A 4h9mA-1asoA:
undetectable
4h9mA-1asoA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 8 ASP A 255
ALA A 226
TYR A 257
SER A 323
None
1.05A 4k0bB-1asoA:
undetectable
4k0bB-1asoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 8 ASP A 255
ALA A 226
TYR A 257
SER A 323
None
1.07A 4l7iB-1asoA:
undetectable
4l7iB-1asoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 LEU A 172
GLY A 176
GLN A 177
LEU A 293
THR A 222
None
1.21A 4p6xE-1asoA:
undetectable
4p6xE-1asoA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 LEU A 172
GLY A 176
GLN A 177
LEU A 293
THR A 222
None
1.21A 4p6xI-1asoA:
undetectable
4p6xI-1asoA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
3 / 3 VAL A 484
PHE A 320
ARG A 283
None
0.85A 4xr4B-1asoA:
undetectable
4xr4B-1asoA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASN A 481
HIS A  62
HIS A 104
HIS A 508
THR A 221
None
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
None
1.37A 4ygfC-1asoA:
undetectable
4ygfC-1asoA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASN A 481
HIS A  62
HIS A 104
HIS A 508
THR A 221
None
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
None
1.36A 4ygfD-1asoA:
undetectable
4ygfD-1asoA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 ASN A 481
HIS A  62
HIS A 104
HIS A 508
THR A 221
None
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
None
1.34A 4yhaA-1asoA:
undetectable
4yhaA-1asoA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASN A 481
HIS A  62
HIS A 104
HIS A 508
THR A 221
None
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
None
1.35A 4yhaC-1asoA:
undetectable
4yhaC-1asoA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 GLY A  26
LEU A 140
ILE A 256
PHE A 102
GLY A 259
None
None
None
CU  A 556 ( 4.9A)
None
1.16A 4ze2A-1asoA:
0.0
4ze2A-1asoA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 GLY A 243
ALA A 241
PHE A 102
SER A 220
GLU A 136
None
None
CU  A 556 ( 4.9A)
None
None
1.31A 5cprB-1asoA:
undetectable
5cprB-1asoA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 GLY A  26
LEU A 140
ILE A 256
PHE A 102
GLY A 259
None
None
None
CU  A 556 ( 4.9A)
None
1.08A 5eskA-1asoA:
undetectable
5eskA-1asoA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 GLY A  74
THR A  75
VAL A  58
HIS A 104
None
None
None
CU  A 556 (-3.1A)
1.02A 5ewuA-1asoA:
undetectable
5ewuA-1asoA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 GLY A  74
THR A  75
VAL A  58
HIS A 104
None
None
None
CU  A 556 (-3.1A)
0.94A 5ewuB-1asoA:
undetectable
5ewuB-1asoA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 11 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.28A 5hwcA-1asoA:
undetectable
5hwcA-1asoA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 GLU A 510
PRO A 511
ILE A 509
LEU A 513
None
None
CU  A 554 ( 4.1A)
None
0.99A 5m45A-1asoA:
0.0
5m45A-1asoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 GLU A 510
PRO A 511
ILE A 509
LEU A 513
None
None
CU  A 554 ( 4.1A)
None
0.94A 5m45D-1asoA:
0.0
5m45D-1asoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 GLU A 510
PRO A 511
ILE A 509
LEU A 513
None
None
CU  A 554 ( 4.1A)
None
0.96A 5m45G-1asoA:
0.0
5m45G-1asoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 GLU A 510
PRO A 511
ILE A 509
LEU A 513
None
None
CU  A 554 ( 4.1A)
None
0.93A 5m45J-1asoA:
0.0
5m45J-1asoA:
20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A  60
HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.18A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 448
HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.65A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 506
HIS A 448
HIS A 106
HIS A 450
HIS A  60
CU  A 555 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
1.44A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A  60
HIS A  62
HIS A 104
HIS A 448
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
0.27A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A  60
HIS A 106
HIS A 448
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.76A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A 448
HIS A 450
HIS A 506
HIS A  60
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
0.62A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 448
HIS A 508
HIS A  60
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 (-3.1A)
0.76A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 508
HIS A 506
HIS A 104
HIS A 106
CU  A 556 (-3.3A)
CU  A 555 (-3.1A)
CU  A 556 (-3.1A)
CU  A 555 (-3.3A)
0.79A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.27A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEJ_A_CUA504_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.15A 5mejA-1asoA:
40.5
5mejA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A  60
HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.17A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 448
HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.64A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 506
HIS A 448
HIS A 106
HIS A 450
HIS A  60
CU  A 555 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
1.44A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A  60
HIS A  62
HIS A 104
HIS A 448
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
0.27A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A  60
HIS A 106
HIS A 448
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.75A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A 448
HIS A 450
HIS A 506
HIS A  60
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
0.63A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 448
HIS A 508
HIS A  60
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 (-3.1A)
0.75A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 508
HIS A 506
HIS A 104
HIS A 106
CU  A 556 (-3.3A)
CU  A 555 (-3.1A)
CU  A 556 (-3.1A)
CU  A 555 (-3.3A)
0.78A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.27A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.81A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MEW_A_CUA504_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mewA-1asoA:
40.5
5mewA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A  60
HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.16A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 448
HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.65A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 506
HIS A 448
HIS A 106
HIS A 450
HIS A  60
CU  A 555 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
1.44A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A  60
HIS A  62
HIS A 104
HIS A 448
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
0.28A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A  60
HIS A 106
HIS A 448
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.76A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A 448
HIS A 450
HIS A 506
HIS A  60
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
0.63A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 448
HIS A 508
HIS A  60
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 (-3.1A)
0.76A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 508
HIS A 506
HIS A 104
HIS A 106
CU  A 556 (-3.3A)
CU  A 555 (-3.1A)
CU  A 556 (-3.1A)
CU  A 555 (-3.3A)
0.78A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.29A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHU_A_CUA504_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mhuA-1asoA:
40.4
5mhuA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A  60
HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.15A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 448
HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.65A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA501_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 5 HIS A 506
HIS A 448
HIS A 106
HIS A 450
HIS A  60
CU  A 555 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
1.44A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A  60
HIS A  62
HIS A 104
HIS A 448
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
0.28A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A  60
HIS A 106
HIS A 448
HIS A 506
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.76A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 6 HIS A 448
HIS A 450
HIS A 506
HIS A  60
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 557 ( 3.1A)
CU  A 555 (-3.3A)
0.63A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 448
HIS A 508
HIS A  60
HIS A 104
CU  A 557 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 (-3.1A)
0.76A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA502_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 6 HIS A 508
HIS A 506
HIS A 104
HIS A 106
CU  A 556 (-3.3A)
CU  A 555 (-3.1A)
CU  A 556 (-3.1A)
CU  A 555 (-3.3A)
0.77A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.21A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.29A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA503_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MHV_A_CUA504_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mhvA-1asoA:
40.5
5mhvA-1asoA:
31.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.98A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.71A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.29A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.21A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.30A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mhwA-1asoA:
40.4
5mhwA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.72A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.29A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.21A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.30A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.13A 5mhxA-1asoA:
40.4
5mhxA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.72A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.30A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.21A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.30A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mhyA-1asoA:
40.5
5mhyA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.72A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.30A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.71A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mhzA-1asoA:
40.4
5mhzA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.72A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.30A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.71A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.21A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.13A 5mi1A-1asoA:
40.5
5mi1A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.72A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.31A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.84A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.30A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mi2A-1asoA:
40.5
5mi2A-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.14A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.72A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.31A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5miaA-1asoA:
40.4
5miaA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.14A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.73A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.31A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mibA-1asoA:
40.4
5mibA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.73A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.31A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.71A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5micA-1asoA:
40.4
5micA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.73A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.31A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5midA-1asoA:
40.5
5midA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A 448
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.13A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 450
HIS A 508
HIS A 448
HIS A 506
CU  A 555 ( 3.2A)
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
0.99A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 508
HIS A  60
HIS A  62
HIS A 104
CU  A 556 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
0.73A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.31A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.70A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.85A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5mieA-1asoA:
40.5
5mieA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
3 / 3 HIS A 106
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
0.12A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  60
HIS A  62
HIS A 104
HIS A 508
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 556 (-3.1A)
CU  A 556 (-3.3A)
0.34A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 448
HIS A 450
HIS A 506
HIS A 106
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 (-3.3A)
0.71A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A 508
HIS A 448
HIS A 506
HIS A 450
CU  A 556 (-3.3A)
CU  A 557 ( 3.2A)
CU  A 555 (-3.1A)
CU  A 555 ( 3.2A)
0.84A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A  60
HIS A  62
HIS A 448
HIS A 450
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
0.22A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 106
HIS A  60
HIS A 450
HIS A 506
CU  A 555 (-3.3A)
CU  A 557 ( 3.1A)
CU  A 555 ( 3.2A)
CU  A 555 (-3.1A)
1.31A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 448
HIS A 450
HIS A  60
HIS A  62
CU  A 557 ( 3.2A)
CU  A 555 ( 3.2A)
CU  A 557 ( 3.1A)
CU  A 556 ( 3.0A)
0.82A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 4 HIS A 445
CYH A 507
ILE A 509
HIS A 512
CU  A 554 (-3.2A)
CU  A 554 (-2.1A)
CU  A 554 ( 4.1A)
CU  A 554 (-3.1A)
0.14A 5migA-1asoA:
40.5
5migA-1asoA:
29.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 7 GLY A 114
LEU A 115
ILE A  27
GLY A  33
ILE A  64
None
1.25A 5vkqA-1asoA:
undetectable
5vkqB-1asoA:
undetectable
5vkqA-1asoA:
14.69
5vkqB-1asoA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 8 GLY A 114
LEU A 115
ILE A  27
GLY A  33
ILE A  64
None
1.25A 5vkqB-1asoA:
undetectable
5vkqC-1asoA:
undetectable
5vkqB-1asoA:
14.69
5vkqC-1asoA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 8 TRP A  61
PHE A  93
HIS A 508
THR A 221
None
None
CU  A 556 (-3.3A)
None
1.16A 5yj1G-1asoA:
undetectable
5yj1Y-1asoA:
0.0
5yj1G-1asoA:
11.49
5yj1Y-1asoA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 8 HIS A 508
THR A 221
TRP A  61
PHE A  93
CU  A 556 (-3.3A)
None
None
None
1.15A 5yj1k-1asoA:
undetectable
5yj1t-1asoA:
0.0
5yj1k-1asoA:
11.49
5yj1t-1asoA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
4 / 5 HIS A  62
HIS A 508
HIS A 104
PHE A 102
CU  A 556 ( 3.0A)
CU  A 556 (-3.3A)
CU  A 556 (-3.1A)
CU  A 556 ( 4.9A)
1.24A 5zrdD-1asoA:
undetectable
5zrdD-1asoA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 10 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.47A 6mkeC-1asoA:
undetectable
6mkeC-1asoA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 10 ASP A 253
ARG A 322
PHE A 326
VAL A 238
ILE A 231
None
1.40A 6mkeD-1asoA:
undetectable
6mkeD-1asoA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 HIS A 106
ILE A  78
SER A  79
HIS A 450
HIS A 448
CU  A 555 (-3.3A)
None
None
CU  A 555 ( 3.2A)
CU  A 557 ( 3.2A)
1.30A 6n91A-1asoA:
undetectable
6n91A-1asoA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)
1aso ASCORBATE OXIDASE
(Cucurbita
pepo)
5 / 12 HIS A 106
ILE A  78
SER A  79
HIS A 450
HIS A 448
CU  A 555 (-3.3A)
None
None
CU  A 555 ( 3.2A)
CU  A 557 ( 3.2A)
1.29A 6n91B-1asoA:
undetectable
6n91B-1asoA:
11.34