SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1atg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		4 / 5 LEU A 126
LEU A 100
SER A  87
LEU A  92
 None
 0.98A 1a4lC-1atgA:
undetectable		 1a4lC-1atgA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 12 GLY A 178
ALA A  88
SER A  87
GLY A 162
LEU A 161
 None
 1.12A 1igxA-1atgA:
undetectable		 1igxA-1atgA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 11 LEU A  85
VAL A 125
GLY A 122
TRP A 105
LEU A 161
 None
 1.36A 1jkhA-1atgA:
undetectable
1jkhB-1atgA:
0.2		 1jkhA-1atgA:
17.84
1jkhB-1atgA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 12 ASN A  10
LEU A 166
ALA A 167
LEU A  18
THR A   7
 WO4  A 250 ( 3.7A)
None
None
None
None
 1.47A 2aa6B-1atgA:
undetectable		 2aa6B-1atgA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 11 LEU A 161
ILE A 108
VAL A 125
GLY A 122
LEU A 100
 None
 1.27A 2bxeA-1atgA:
undetectable		 2bxeA-1atgA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 12 ILE A 110
ILE A 141
ILE A 108
PHE A 163
VAL A  93
 None
 1.06A 2ygoA-1atgA:
0.0		 2ygoA-1atgA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		6 / 12 GLY A 162
ILE A 169
ASP A 160
VAL A  84
HIS A 180
LEU A  85
 None
None
ACT  A 301 (-3.5A)
None
None
None
 1.38A 2yqzA-1atgA:
undetectable		 2yqzA-1atgA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		6 / 12 GLY A 162
ILE A 169
ASP A 160
VAL A  84
HIS A 180
LEU A  85
 None
None
ACT  A 301 (-3.5A)
None
None
None
 1.37A 2yqzB-1atgA:
undetectable		 2yqzB-1atgA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		4 / 7 ILE A 115
GLY A  38
SER A  37
SER A  36
 None
None
WO4  A 250 ( 2.7A)
None
 0.85A 3v7pA-1atgA:
0.0		 3v7pA-1atgA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 11 THR A   7
VAL A  30
ILE A  32
PHE A  54
LEU A  12
 None
 1.39A 4lhmA-1atgA:
undetectable		 4lhmA-1atgA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 9 LEU A  15
ALA A  19
LEU A   3
GLN A 209
PHE A 210
 None
 1.35A 4ltwA-1atgA:
0.0		 4ltwA-1atgA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		4 / 7 VAL A 142
ILE A 141
TRP A 105
LEU A  85
 None
 1.01A 4xo7A-1atgA:
undetectable		 4xo7A-1atgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 9 PHE A 163
GLY A 122
ILE A  80
LYS A  82
ASP A  57
 None
 1.32A 6c2mC-1atgA:
undetectable		 6c2mC-1atgA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 1atg PERIPLASMIC
MOLYBDATE-BINDING
PROTEIN
(Azotobacter
vinelandii) 		5 / 12 ILE A 223
ASN A  10
PHE A  11
ALA A 195
LEU A  15
 None
WO4  A 250 ( 3.7A)
None
None
None
 1.03A 6dwnD-1atgA:
0.0		 6dwnD-1atgA:
17.32