SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1atj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		3 / 3 LEU A 166
SER A 161
ASN A 158
 HEM  A 350 (-4.0A)
None
None
 0.68A 1bx4A-1atjA:
undetectable		 1bx4A-1atjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		4 / 8 ALA A 134
LEU A 145
LEU A 148
SER A 151
 None
None
HEM  A 350 ( 4.7A)
None
 0.92A 1dvtA-1atjA:
undetectable
1dvtB-1atjA:
undetectable		 1dvtA-1atjA:
15.69
1dvtB-1atjA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		4 / 8 ALA A  51
LEU A 100
LEU A 101
LYS A  84
 None
 0.80A 1e7cA-1atjA:
0.7		 1e7cA-1atjA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 PHE A 277
GLY A 114
GLY A 113
LEU A  37
LEU A  26
 None
None
None
HEM  A 350 ( 4.7A)
None
 1.07A 1ya4B-1atjA:
undetectable		 1ya4B-1atjA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		4 / 7 VAL A 263
TYR A 234
ASN A 236
GLY A 242
 None
 0.80A 2y05A-1atjA:
undetectable
2y05B-1atjA:
undetectable		 2y05A-1atjA:
21.90
2y05B-1atjA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		3 / 3 LEU A  54
VAL A  95
ARG A 298
 None
 0.81A 3b0wB-1atjA:
0.0		 3b0wB-1atjA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_B_ACTB1001_0
(FORMIN-LIKE PROTEIN
3)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		4 / 4 VAL A 235
ASN A 231
ASN A 236
ARG A 224
 None
 1.20A 4eahB-1atjA:
0.0
4eahC-1atjA:
0.0		 4eahB-1atjA:
21.36
4eahC-1atjA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		4 / 7 GLU A  25
THR A  21
LEU A  54
SER A 108
 None
 0.88A 4pfjA-1atjA:
undetectable		 4pfjA-1atjA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 ILE A  53
ALA A  74
THR A  21
VAL A  18
LEU A 101
 None
 1.21A 4qynA-1atjA:
0.0		 4qynA-1atjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 PHE A  77
ILE A  53
ALA A  74
THR A  21
LEU A 101
 None
 1.32A 4qynA-1atjA:
0.0		 4qynA-1atjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 ILE A  53
ALA A  74
THR A  21
VAL A  18
LEU A 101
 None
 1.26A 4qzuA-1atjA:
0.0		 4qzuA-1atjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 PHE A  77
ILE A  53
ALA A  74
THR A  21
LEU A 101
 None
 1.37A 4qzuA-1atjA:
0.0		 4qzuA-1atjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 ALA A 165
GLY A 168
SER A 167
LEU A 250
ASP A 222
 None
None
HEM  A 350 ( 3.7A)
None
CA  A 351 (-3.3A)
 1.49A 5vlmF-1atjA:
0.0		 5vlmF-1atjA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 1atj PEROXIDASE C1A
(Armoracia
rusticana) 		5 / 12 VAL A 155
PHE A 152
PHE A  45
PHE A 179
ILE A 244
 None
HEM  A 350 ( 4.8A)
None
HEM  A 350 (-4.3A)
None
 1.29A 6becA-1atjA:
undetectable
6becB-1atjA:
undetectable
6becC-1atjA:
undetectable		 6becA-1atjA:
17.79
6becB-1atjA:
17.79
6becC-1atjA:
17.79