SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_A_IBPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 9	VAL A 194 VAL A 129 ILE A 182 ALA A 187 SER A 189	BOG A 2 (-4.5A) None None None None	1.20A	1eqgA-1auaA: 0.0	1eqgA-1auaA: 19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RRJ_B_TTCB990_1 (DNA TOPOISOMERASE I)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	4 / 5	GLU A 207 ARG A 119 LYS A 116 ASP A 115	BOG A 1 (-2.9A) None None None	1.37A	1rrjA-1auaA: 0.0	1rrjA-1auaA: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S3Z_B_RIOB501_0 (AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	4 / 8	GLU A 80 TRP A 82 GLU A 152 ASP A 89	None	1.10A	1s3zA-1auaA: 1.7 1s3zB-1auaA: 0.9	1s3zA-1auaA: 20.00 1s3zB-1auaA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.24A	1v8bA-1auaA: undetectable	1v8bA-1auaA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V8B_B_ADNB1502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.24A	1v8bB-1auaA: undetectable	1v8bB-1auaA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PH9_A_GNTA301_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	4 / 7	TYR A 111 TRP A 285 GLN A 109 ILE A 282	None	1.34A	2ph9A-1auaA: undetectable 2ph9B-1auaA: undetectable	2ph9A-1auaA: 23.05 2ph9B-1auaA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RCT_A_RTLA140_0 (RETINOL-BINDING PROTEIN II, CELLULAR)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	MET A 75 ALA A 64 ARG A 60 TYR A 205 VAL A 148	None BOG A 1 ( 4.5A) None None None	1.10A	2rctA-1auaA: undetectable	2rctA-1auaA: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_A_2FAA500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.25A	2zj0A-1auaA: undetectable	2zj0A-1auaA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_D_2FAD500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.34A	2zj0D-1auaA: undetectable	2zj0D-1auaA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_A_ADNA500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	3ce6A-1auaA: undetectable	3ce6A-1auaA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_B_ADNB500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.25A	3ce6B-1auaA: undetectable	3ce6B-1auaA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_C_ADNC500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.27A	3ce6C-1auaA: undetectable	3ce6C-1auaA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_D_ADND500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	3ce6D-1auaA: undetectable	3ce6D-1auaA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CYX_A_ROCA201_3 (HIV-1 PROTEASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	GLY A 244 ALA A 217 ILE A 182 GLY A 181 ILE A 214	None	0.95A	3cyxB-1auaA: undetectable	3cyxB-1auaA: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_C_ADNC438_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.32A	3g1uC-1auaA: undetectable	3g1uC-1auaA: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_A_RABA602_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	3glqA-1auaA: undetectable	3glqA-1auaA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_B_RABB602_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.30A	3glqB-1auaA: undetectable	3glqB-1auaA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_A_ADNA500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.25A	3n58A-1auaA: undetectable	3n58A-1auaA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_C_ADNC500_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	3n58C-1auaA: undetectable	3n58C-1auaA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OND_A_ADNA506_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.29A	3ondA-1auaA: undetectable	3ondA-1auaA: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3THR_A_C2FA1100_0 (GLYCINE N-METHYLTRANSFERASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	4 / 6	LEU A 169 HIS A 168 THR A 25 ARG A 63	None	1.21A	3thrB-1auaA: 0.0	3thrB-1auaA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_A_ADNA501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.30A	4lvcA-1auaA: undetectable	4lvcA-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_C_ADNC501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	4lvcC-1auaA: undetectable	4lvcC-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.24A	4pfjA-1auaA: undetectable	4pfjA-1auaA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	5axaA-1auaA: undetectable	5axaA-1auaA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	5axaC-1auaA: undetectable	5axaC-1auaA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXD_C_RBVC502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.29A	5axdC-1auaA: undetectable	5axdC-1auaA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_B_SAMB301_1 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	3 / 3	ASP A 54 GLU A 80 SER A 163	None	0.84A	5bw4B-1auaA: undetectable	5bw4B-1auaA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_A_1GNA615_1 (PHIAB6 TAILSPIKE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	3 / 3	TYR A 193 TYR A 122 GLN A 109	None	1.07A	5jsdA-1auaA: 0.0 5jsdB-1auaA: 0.0	5jsdA-1auaA: 17.03 5jsdB-1auaA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB606_1 (PHIAB6 TAILSPIKE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	3 / 3	TYR A 193 TYR A 122 GLN A 109	None	1.07A	5jsdB-1auaA: 0.0 5jsdC-1auaA: 0.0	5jsdB-1auaA: 17.03 5jsdC-1auaA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.27A	5m5kA-1auaA: undetectable	5m5kA-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.30A	5m66A-1auaA: undetectable	5m66A-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	5m66B-1auaA: undetectable	5m66B-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.29A	5m66C-1auaA: undetectable	5m66C-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_D_ADND502_1 (ADENOSYLHOMOCYSTEINA SE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.30A	5m66D-1auaA: undetectable	5m66D-1auaA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	4 / 5	LEU A 37 CYH A 17 LEU A 169 ASP A 54	None	1.31A	5mafA-1auaA: undetectable	5mafA-1auaA: 16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_A_ADNA502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	5v96A-1auaA: undetectable	5v96A-1auaA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_B_ADNB502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	5v96B-1auaA: undetectable	5v96B-1auaA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_C_ADNC502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	5v96C-1auaA: undetectable	5v96C-1auaA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_D_ADND502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	5v96D-1auaA: undetectable	5v96D-1auaA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DGX_A_017A101_2 (PROTEASE)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	3 / 3	GLY A 181 ASP A 178 ILE A 214	None	0.56A	6dgxB-1auaA: 0.0	6dgxB-1auaA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_B_ADNB502_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	6f3mB-1auaA: 0.4	6f3mB-1auaA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_D_ADND502_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	6f3mD-1auaA: 1.2	6f3mD-1auaA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_A_ADNA505_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	6f3nA-1auaA: undetectable	6f3nA-1auaA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_B_ADNB505_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	6f3nB-1auaA: undetectable	6f3nB-1auaA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_C_ADNC505_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	6f3nC-1auaA: undetectable	6f3nC-1auaA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_D_ADND506_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.26A	6f3nD-1auaA: undetectable	6f3nD-1auaA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_A_ADNA501_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	6gbnA-1auaA: undetectable	6gbnA-1auaA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_C_ADNC501_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.28A	6gbnC-1auaA: undetectable	6gbnC-1auaA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_D_ADND501_1 (-)	1aua	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P (Saccharomyces cerevisiae)	5 / 12	THR A 25 ASP A 20 LYS A 116 ASP A 117 LEU A 22	None	1.29A	6gbnD-1auaA: undetectable	6gbnD-1auaA: 21.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQG_A_IBPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"VAL A 194;VAL A 129;ILE A 182;ALA A 187;SER A 189","BOG A   2 (-4.5A);None;None;None;None","1.20A","1eqgA-1auaA:0.0","1eqgA-1auaA:19.43"],["1RRJ_B_TTCB990_1","DNA TOPOISOMERASE I","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",4,"GLU A 207;ARG A 119;LYS A 116;ASP A 115","BOG A   1 (-2.9A);None;None;None","1.37A","1rrjA-1auaA:0.0","1rrjA-1auaA:19.40"],["1S3Z_B_RIOB501_0","AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",4,"GLU A  80;TRP A  82;GLU A 152;ASP A  89","None","1.10A","1s3zA-1auaA:1.7;1s3zB-1auaA:0.9","1s3zA-1auaA:20.00;1s3zB-1auaA:20.00"],["1V8B_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.24A","1v8bA-1auaA:undetectable","1v8bA-1auaA:21.60"],["1V8B_B_ADNB1502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.24A","1v8bB-1auaA:undetectable","1v8bB-1auaA:21.60"],["2PH9_A_GNTA301_1","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",4,"TYR A 111;TRP A 285;GLN A 109;ILE A 282","None","1.34A","2ph9A-1auaA:undetectable;2ph9B-1auaA:undetectable","2ph9A-1auaA:23.05;2ph9B-1auaA:23.05"],["2RCT_A_RTLA140_0","RETINOL-BINDING PROTEIN II, CELLULAR","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"MET A  75;ALA A  64;ARG A  60;TYR A 205;VAL A 148","None;BOG A   1 ( 4.5A);None;None;None","1.10A","2rctA-1auaA:undetectable","2rctA-1auaA:16.55"],["2ZJ0_A_2FAA500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.25A","2zj0A-1auaA:undetectable","2zj0A-1auaA:20.16"],["2ZJ0_D_2FAD500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.34A","2zj0D-1auaA:undetectable","2zj0D-1auaA:20.16"],["3CE6_A_ADNA500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","3ce6A-1auaA:undetectable","3ce6A-1auaA:20.20"],["3CE6_B_ADNB500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.25A","3ce6B-1auaA:undetectable","3ce6B-1auaA:20.20"],["3CE6_C_ADNC500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.27A","3ce6C-1auaA:undetectable","3ce6C-1auaA:20.20"],["3CE6_D_ADND500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","3ce6D-1auaA:undetectable","3ce6D-1auaA:20.20"],["3CYX_A_ROCA201_3","HIV-1 PROTEASE;HIV-1 PROTEASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"GLY A 244;ALA A 217;ILE A 182;GLY A 181;ILE A 214","None","0.95A","3cyxB-1auaA:undetectable","3cyxB-1auaA:18.73"],["3G1U_C_ADNC438_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.32A","3g1uC-1auaA:undetectable","3g1uC-1auaA:19.69"],["3GLQ_A_RABA602_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","3glqA-1auaA:undetectable","3glqA-1auaA:21.38"],["3GLQ_B_RABB602_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.30A","3glqB-1auaA:undetectable","3glqB-1auaA:21.38"],["3N58_A_ADNA500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.25A","3n58A-1auaA:undetectable","3n58A-1auaA:21.32"],["3N58_C_ADNC500_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","3n58C-1auaA:undetectable","3n58C-1auaA:21.32"],["3OND_A_ADNA506_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.29A","3ondA-1auaA:undetectable","3ondA-1auaA:20.37"],["3THR_A_C2FA1100_0","GLYCINE N-METHYLTRANSFERASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",4,"LEU A 169;HIS A 168;THR A  25;ARG A  63","None","1.21A","3thrB-1auaA:0.0","3thrB-1auaA:21.74"],["4LVC_A_ADNA501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.30A","4lvcA-1auaA:undetectable","4lvcA-1auaA:21.43"],["4LVC_C_ADNC501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","4lvcC-1auaA:undetectable","4lvcC-1auaA:21.43"],["4PFJ_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.24A","4pfjA-1auaA:undetectable","4pfjA-1auaA:21.79"],["5AXA_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","5axaA-1auaA:undetectable","5axaA-1auaA:21.99"],["5AXA_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","5axaC-1auaA:undetectable","5axaC-1auaA:21.99"],["5AXD_C_RBVC502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.29A","5axdC-1auaA:undetectable","5axdC-1auaA:21.99"],["5BW4_B_SAMB301_1","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",3,"ASP A  54;GLU A  80;SER A 163","None","0.84A","5bw4B-1auaA:undetectable","5bw4B-1auaA:23.17"],["5JSD_A_1GNA615_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",3,"TYR A 193;TYR A 122;GLN A 109","None","1.07A","5jsdA-1auaA:0.0;5jsdB-1auaA:0.0","5jsdA-1auaA:17.03;5jsdB-1auaA:17.03"],["5JSD_B_1GNB606_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",3,"TYR A 193;TYR A 122;GLN A 109","None","1.07A","5jsdB-1auaA:0.0;5jsdC-1auaA:0.0","5jsdB-1auaA:17.03;5jsdC-1auaA:17.03"],["5M5K_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.27A","5m5kA-1auaA:undetectable","5m5kA-1auaA:21.43"],["5M66_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.30A","5m66A-1auaA:undetectable","5m66A-1auaA:21.43"],["5M66_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","5m66B-1auaA:undetectable","5m66B-1auaA:21.43"],["5M66_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.29A","5m66C-1auaA:undetectable","5m66C-1auaA:21.43"],["5M66_D_ADND502_1","ADENOSYLHOMOCYSTEINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.30A","5m66D-1auaA:undetectable","5m66D-1auaA:21.43"],["5MAF_A_XINA403_2","MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",4,"LEU A  37;CYH A  17;LEU A 169;ASP A  54","None","1.31A","5mafA-1auaA:undetectable","5mafA-1auaA:16.59"],["5V96_A_ADNA502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","5v96A-1auaA:undetectable","5v96A-1auaA:21.96"],["5V96_B_ADNB502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","5v96B-1auaA:undetectable","5v96B-1auaA:21.96"],["5V96_C_ADNC502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","5v96C-1auaA:undetectable","5v96C-1auaA:21.96"],["5V96_D_ADND502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","5v96D-1auaA:undetectable","5v96D-1auaA:21.96"],["6DGX_A_017A101_2","PROTEASE","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",3,"GLY A 181;ASP A 178;ILE A 214","None","0.56A","6dgxB-1auaA:0.0","6dgxB-1auaA:14.34"],["6F3M_B_ADNB502_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","6f3mB-1auaA:0.4","6f3mB-1auaA:20.39"],["6F3M_D_ADND502_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","6f3mD-1auaA:1.2","6f3mD-1auaA:20.39"],["6F3N_A_ADNA505_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","6f3nA-1auaA:undetectable","6f3nA-1auaA:20.08"],["6F3N_B_ADNB505_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","6f3nB-1auaA:undetectable","6f3nB-1auaA:20.08"],["6F3N_C_ADNC505_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","6f3nC-1auaA:undetectable","6f3nC-1auaA:20.08"],["6F3N_D_ADND506_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.26A","6f3nD-1auaA:undetectable","6f3nD-1auaA:20.08"],["6GBN_A_ADNA501_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","6gbnA-1auaA:undetectable","6gbnA-1auaA:21.21"],["6GBN_C_ADNC501_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.28A","6gbnC-1auaA:undetectable","6gbnC-1auaA:21.21"],["6GBN_D_ADND501_1","-","1aua","PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P","Saccharomyces cerevisiae",5,"THR A  25;ASP A  20;LYS A 116;ASP A 117;LEU A  22","None","1.29A","6gbnD-1auaA:undetectable","6gbnD-1auaA:21.21"]]