SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.81A 1a7yB-1aunA:
undetectable		 1a7yB-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.80A 1dscC-1aunA:
undetectable		 1dscC-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.67A 1dscC-1aunA:
undetectable		 1dscC-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.75A 1fjaC-1aunA:
undetectable		 1fjaC-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.75A 1fjaD-1aunA:
undetectable		 1fjaD-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.86A 1i3wE-1aunA:
undetectable		 1i3wE-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.83A 1i3wG-1aunA:
undetectable		 1i3wG-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.83A 1i3wH-1aunA:
undetectable		 1i3wH-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.79A 1mnvD-1aunA:
undetectable		 1mnvD-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.84A 1unjL-1aunA:
undetectable		 1unjL-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.79A 1unjL-1aunA:
undetectable		 1unjL-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.82A 1unjR-1aunA:
undetectable		 1unjR-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.81A 1unjR-1aunA:
undetectable		 1unjR-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.77A 1unjW-1aunA:
undetectable		 1unjW-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.80A 1unjX-1aunA:
undetectable		 1unjX-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.83A 1unjX-1aunA:
undetectable		 1unjX-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.82A 1unmE-1aunA:
undetectable		 1unmE-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.79A 1unmE-1aunA:
undetectable		 1unmE-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.83A 1unmF-1aunA:
undetectable		 1unmF-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 188
THR A 190
PRO A 187
 None
 0.79A 1unmF-1aunA:
undetectable		 1unmF-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1aun PR-5D
(Nicotiana
tabacum) 		5 / 12 THR A  64
GLY A 104
GLY A 143
ASP A  98
ILE A  99
 None
 1.16A 2b25B-1aunA:
undetectable		 2b25B-1aunA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1aun PR-5D
(Nicotiana
tabacum) 		5 / 8 GLY A  24
GLY A  23
ALA A  16
ALA A  17
PHE A  35
 None
 1.30A 2ha4A-1aunA:
undetectable		 2ha4A-1aunA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 THR A 190
PRO A 187
THR A 188
 None
 0.84A 316dC-1aunA:
undetectable		 316dC-1aunA:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 GLY A   2
VAL A   3
ASP A 199
THR A 198
 None
 1.24A 3vqrB-1aunA:
undetectable		 3vqrB-1aunA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.39A 3w9tA-1aunA:
0.0		 3w9tA-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.40A 3w9tB-1aunA:
undetectable		 3w9tB-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.40A 3w9tC-1aunA:
undetectable		 3w9tC-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.39A 3w9tD-1aunA:
0.0		 3w9tD-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.40A 3w9tE-1aunA:
0.0		 3w9tE-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.39A 3w9tF-1aunA:
0.0		 3w9tF-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 5 VAL A   3
GLY A   2
TYR A 200
ASP A  95
 None
 1.41A 3w9tG-1aunA:
0.0		 3w9tG-1aunA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 4 ASN A 106
SER A 137
LEU A 138
THR A  64
 None
 1.28A 4an2A-1aunA:
0.0		 4an2A-1aunA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 ASN A  89
ASP A  95
ASP A 199
 None
 0.87A 4obwD-1aunA:
undetectable		 4obwD-1aunA:
21.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1aun PR-5D
(Nicotiana
tabacum) 		4 / 7 LEU A  83
GLU A  85
SER A 100
ILE A 102
 None
 0.17A 4tvtA-1aunA:
33.6		 4tvtA-1aunA:
52.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1aun PR-5D
(Nicotiana
tabacum) 		3 / 3 GLY A  48
THR A  50
ASN A 106
 None
 0.54A 5odiG-1aunA:
undetectable		 5odiG-1aunA:
16.42