SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A  24
GLY A  22
LEU A  20
GLY A 112
PRO A 143
 None
PMS  A 801 ( 3.9A)
None
None
None
 1.22A 1y4lA-1aurA:
undetectable		 1y4lA-1aurA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		4 / 8 PHE A 125
ALA A 142
PHE A 145
ALA A 137
 None
 0.92A 3t3sD-1aurA:
undetectable		 3t3sD-1aurA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		3 / 3 LYS A 184
GLU A 181
TRP A 192
 None
 1.24A 3v4tH-1aurA:
0.7		 3v4tH-1aurA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA703_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		4 / 4 LEU A 138
PHE A 113
LEU A 202
GLU A 205
 None
 1.38A 4p7nA-1aurA:
0.0		 4p7nA-1aurA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		3 / 3 PRO A 196
MET A 197
TYR A 195
 None
 0.96A 4qa0B-1aurA:
1.1		 4qa0B-1aurA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		3 / 3 PRO A 196
MET A 197
TYR A 195
 None
 0.94A 4qa0A-1aurA:
2.9		 4qa0A-1aurA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		3 / 3 PRO A 196
MET A 197
TYR A 195
 None
 0.89A 4qa2B-1aurA:
2.8		 4qa2B-1aurA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		5 / 11 THR A 123
ALA A 124
GLY A 116
GLY A 117
ALA A 118
 None
 0.97A 5lf3K-1aurA:
undetectable
5lf3L-1aurA:
undetectable		 5lf3K-1aurA:
21.93
5lf3L-1aurA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1aur CARBOXYLESTERASE
(Pseudomonas
fluorescens) 		5 / 11 THR A 123
ALA A 124
GLY A 116
GLY A 117
ALA A 118
 None
 0.98A 5lf3Y-1aurA:
undetectable
5lf3Z-1aurA:
undetectable		 5lf3Y-1aurA:
21.93
5lf3Z-1aurA:
22.36