SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ava'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		5 / 12 ILE C  73
LEU C  76
LEU C  14
TYR C 139
ILE C 128
 None
 1.17A 1fmlB-1avaC:
undetectable		 1fmlB-1avaC:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		4 / 8 GLY C 159
SER C  48
ASP C  50
THR C  34
 None
 0.89A 1m4iA-1avaC:
0.0		 1m4iA-1avaC:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		4 / 6 HIS C 108
PHE C 163
GLY C 159
LYS C 158
 None
 0.95A 2i30A-1avaC:
undetectable		 2i30A-1avaC:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		5 / 8 LEU C 102
HIS C 108
PHE C 163
GLY C 159
LYS C 158
 None
 1.43A 3b9lA-1avaC:
undetectable		 3b9lA-1avaC:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		4 / 6 GLY C  31
GLY C  30
SER C  24
HIS C 171
 None
 0.78A 3o9mB-1avaC:
undetectable		 3o9mB-1avaC:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		4 / 6 GLY C  32
GLY C  31
SER C  24
HIS C 171
 None
 0.76A 3o9mB-1avaC:
undetectable		 3o9mB-1avaC:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		3 / 3 PHE C 163
ASP C  99
ARG C  41
 None
 0.89A 4eahF-1avaC:
undetectable		 4eahF-1avaC:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		3 / 3 PHE C 163
ASP C  99
ARG C  41
 None
 0.89A 4eahG-1avaC:
undetectable		 4eahG-1avaC:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		4 / 6 SER C  70
ASP C  79
ARG C 127
GLU C 129
 None
 0.99A 5cdqA-1avaC:
0.0
5cdqC-1avaC:
0.0
5cdqD-1avaC:
undetectable		 5cdqA-1avaC:
17.35
5cdqC-1avaC:
17.35
5cdqD-1avaC:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 1ava BARLEY
ALPHA-AMYLASE/SUBTIL
ISIN INHIBITOR
(Hordeum
vulgare) 		5 / 12 HIS C  39
GLY C  38
PHE C 163
ASP C 156
LEU C 157
 None
 1.45A 5eeiB-1avaC:
undetectable		 5eeiB-1avaC:
19.61