SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1avg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 1avg TRIABIN
(Meccus
pallidipennis) 		4 / 7 GLY I  30
TYR I  58
LEU I  27
ALA I  28
 None
 0.84A 1dmaA-1avgI:
undetectable		 1dmaA-1avgI:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1avg TRIABIN
(Meccus
pallidipennis) 		3 / 3 PHE I  82
PHE I  96
PHE I  98
 None
 0.79A 2od9A-1avgI:
undetectable		 2od9A-1avgI:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1avg TRIABIN
(Meccus
pallidipennis) 		3 / 3 PHE I  82
PHE I  96
PHE I  98
 None
 0.79A 2qqgA-1avgI:
undetectable		 2qqgA-1avgI:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 1avg TRIABIN
(Meccus
pallidipennis) 		4 / 6 PHE I  21
TYR I  80
VAL I 109
PHE I  15
 None
 1.33A 3ltwA-1avgI:
undetectable		 3ltwA-1avgI:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 1avg TRIABIN
(Meccus
pallidipennis) 		4 / 6 PHE I  82
TYR I  80
VAL I 109
PHE I  21
 None
 1.22A 3ltwA-1avgI:
undetectable		 3ltwA-1avgI:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 1avg TRIABIN
(Meccus
pallidipennis) 		3 / 3 PHE I  67
VAL I  38
GLU I  55
 None
 0.71A 4fvqA-1avgI:
0.0		 4fvqA-1avgI:
18.37