SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1avm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1avm SUPEROXIDE DISMUTASE
(Propionibacteriu
m
freudenreichii) 		5 / 12 PHE A 143
GLY A 125
SER A 124
ALA A 127
ALA A 118
 None
 1.31A 1nw5A-1avmA:
undetectable		 1nw5A-1avmA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 1avm SUPEROXIDE DISMUTASE
(Propionibacteriu
m
freudenreichii) 		3 / 3 ARG A 199
ASP A 101
ASP A 108
 None
 0.87A 2ejtA-1avmA:
undetectable		 2ejtA-1avmA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1avm SUPEROXIDE DISMUTASE
(Propionibacteriu
m
freudenreichii) 		5 / 11 ILE A 100
ASP A 108
ALA A 112
THR A 115
VAL A 179
 None
 1.18A 3rukD-1avmA:
undetectable		 3rukD-1avmA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1avm SUPEROXIDE DISMUTASE
(Propionibacteriu
m
freudenreichii) 		5 / 12 LEU A 160
ASN A 149
PHE A 143
ASN A  74
HIS A 165
 None
None
None
None
FE  A 202 (-3.3A)
 1.47A 5d0yB-1avmA:
0.0		 5d0yB-1avmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1avm SUPEROXIDE DISMUTASE
(Propionibacteriu
m
freudenreichii) 		3 / 3 SER A  76
LEU A  15
MET A  82
 None
 0.82A 5ikrB-1avmA:
0.0		 5ikrB-1avmA:
16.04