SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1avq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1avq LAMBDA EXONUCLEASE
(Escherichia
virus
Lambda) 		4 / 8 ILE A  41
ILE A 202
SER A 198
GLU A 201
 None
None
ACT  A 228 (-3.6A)
None
 0.69A 1mrjA-1avqA:
undetectable		 1mrjA-1avqA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1avq LAMBDA EXONUCLEASE
(Escherichia
virus
Lambda) 		4 / 7 TYR A 107
LEU A  27
VAL A  14
ILE A   5
 None
 0.96A 1t87B-1avqA:
0.0		 1t87B-1avqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1avq LAMBDA EXONUCLEASE
(Escherichia
virus
Lambda) 		4 / 8 TYR A 107
LEU A  27
VAL A  14
ILE A   5
 None
 1.00A 4l4cB-1avqA:
undetectable		 4l4cB-1avqA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 1avq LAMBDA EXONUCLEASE
(Escherichia
virus
Lambda) 		3 / 3 PHE A 142
ASP A 138
LYS A 141
 None
 0.78A 6awtD-1avqA:
0.0		 6awtD-1avqA:
20.64