SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1avw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1avw TRYPSIN INHIBITOR
(Glycine
max) 		5 / 8 ILE B 558
LEU B 573
ILE B 567
GLU B 569
VAL B 503
 None
 1.26A 1linA-1avwB:
undetectable		 1linA-1avwB:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1avw TRYPSIN INHIBITOR
(Glycine
max) 		6 / 12 ALA B 531
SER B 579
PHE B 580
GLY B 555
THR B 516
TYR B 518
 None
 1.31A 2zifB-1avwB:
undetectable		 2zifB-1avwB:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1avw TRYPSIN INHIBITOR
(Glycine
max) 		4 / 6 VAL B 670
SER B 521
ILE B 519
PHE B 673
 None
 1.03A 5jw1B-1avwB:
0.0		 5jw1B-1avwB:
15.74