SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1aw9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1aw9 GLUTATHIONE
S-TRANSFERASE III
(Zea
mays) 		5 / 12 LEU A 157
ALA A 158
THR A  84
LEU A  87
PRO A  88
 None
 1.24A 1og5A-1aw9A:
undetectable		 1og5A-1aw9A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 1aw9 GLUTATHIONE
S-TRANSFERASE III
(Zea
mays) 		3 / 3 ALA A 170
THR A  20
PHE A 107
 None
 0.78A 2c6nB-1aw9A:
0.0		 2c6nB-1aw9A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1aw9 GLUTATHIONE
S-TRANSFERASE III
(Zea
mays) 		4 / 6 ARG A  17
PRO A  56
GLU A  67
SER A  68
 None
 0.93A 3vlnA-1aw9A:
19.9		 3vlnA-1aw9A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1aw9 GLUTATHIONE
S-TRANSFERASE III
(Zea
mays) 		4 / 7 LEU A 119
PRO A 212
VAL A  16
MET A   9
 None
 1.27A 4klrA-1aw9A:
undetectable		 4klrA-1aw9A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1aw9 GLUTATHIONE
S-TRANSFERASE III
(Zea
mays) 		4 / 6 LEU A  11
VAL A  16
THR A  20
LEU A 213
 None
 0.98A 5tudD-1aw9A:
undetectable		 5tudD-1aw9A:
21.35