SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1axi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1axi GROWTH HORMONE
RECEPTOR
(Homo
sapiens) 		5 / 11 GLY B 148
ILE B 153
SER B 201
LEU B 202
VAL B 204
 SO4  B 237 (-3.3A)
None
None
None
None
 1.06A 3gyqB-1axiB:
undetectable		 3gyqB-1axiB:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1axi GROWTH HORMONE
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU B 141
ILE B 153
SER B 201
LEU B 202
VAL B 204
 None
 1.10A 3gyqB-1axiB:
undetectable		 3gyqB-1axiB:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1axi GROWTH HORMONE
RECEPTOR
(Homo
sapiens) 		4 / 8 PHE B  35
ILE B 128
LEU B  66
PHE B  96
 None
 1.03A 3rqwI-1axiB:
1.2
3rqwJ-1axiB:
1.2		 3rqwI-1axiB:
17.96
3rqwJ-1axiB:
17.96