SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ay2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ay2 TYPE 4 PILIN
(Neisseria
gonorrhoeae) 		5 / 12 GLY A  65
SER A  63
ALA A  64
SER A  71
PRO A  70
 None
NAG  A 161 (-1.4A)
None
None
None
 1.35A 2vmyB-1ay2A:
undetectable		 2vmyB-1ay2A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ay2 TYPE 4 PILIN
(Neisseria
gonorrhoeae) 		4 / 5 ARG A 127
VAL A  88
LEU A 108
SER A 107
 None
 1.33A 4e1gA-1ay2A:
undetectable		 4e1gA-1ay2A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 1ay2 TYPE 4 PILIN
(Neisseria
gonorrhoeae) 		5 / 12 ALA A  46
TYR A  50
VAL A  47
SER A  63
GLY A  65
 None
None
None
NAG  A 161 (-1.4A)
None
 1.20A 4mm4B-1ay2A:
undetectable		 4mm4B-1ay2A:
15.18