SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ayy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY B 214
ALA B 202
THR B 201
ALA B 200
ALA B 235
 None
 0.99A 2gluB-1ayyB:
undetectable		 2gluB-1ayyB:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 ILE B 153
ALA B 157
GLY B 166
GLY B 154
VAL B 193
 None
 1.18A 2okcB-1ayyB:
undetectable		 2okcB-1ayyB:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 8 ALA B 202
GLY B 188
ILE B 186
THR B 212
 None
 0.68A 3so9A-1ayyB:
0.0		 3so9A-1ayyB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 12 GLY B 214
GLY B 188
VAL B 218
THR B 215
VAL B 255
 None
 1.21A 4f84A-1ayyB:
undetectable		 4f84A-1ayyB:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 11 GLN B 230
ALA B 231
THR B 215
VAL B 193
LEU B 164
 None
 1.15A 4j6cA-1ayyB:
undetectable		 4j6cA-1ayyB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 10 GLN B 230
ALA B 231
THR B 215
VAL B 193
LEU B 164
 None
 1.18A 4j6cB-1ayyB:
undetectable		 4j6cB-1ayyB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 9 ILE B 186
GLY B 190
ILE B 210
GLU B 207
ARG B 180
 None
 1.14A 4yp2B-1ayyB:
undetectable		 4yp2B-1ayyB:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		5 / 9 ILE B 186
GLY B 190
ILE B 210
GLU B 207
ARG B 180
 None
 1.17A 5cf9B-1ayyB:
undetectable		 5cf9B-1ayyB:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1ayy GLYCOSYLASPARAGINASE
(Elizabethkingia
meningoseptica) 		4 / 7 ILE B 239
GLU B 207
HIS B 205
VAL B 255
 None
 1.10A 6j20A-1ayyB:
0.0		 6j20A-1ayyB:
14.54