SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1azw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		3 / 3 TRP A 197
VAL A 199
TRP A 200
 None
 1.32A 1gmkC-1azwA:
undetectable
1gmkD-1azwA:
undetectable		 1gmkC-1azwA:
6.85
1gmkD-1azwA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 11 SER A  71
GLY A  72
GLY A  46
MET A  52
PHE A 222
 None
 1.33A 1iolA-1azwA:
4.2		 1iolA-1azwA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 11 GLY A  42
GLY A  43
SER A 110
PHE A 226
HIS A 294
 None
 1.06A 1w76A-1azwA:
12.2		 1w76A-1azwA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 10 GLY A  42
GLY A  43
SER A 110
PHE A 234
HIS A 294
 None
 0.90A 1w76B-1azwA:
12.4		 1w76B-1azwA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 PHE A 234
GLY A  43
GLY A  42
LEU A 138
LEU A 132
 None
 0.87A 1ya4C-1azwA:
12.5		 1ya4C-1azwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A 286
ILE A 288
HIS A 294
GLY A 263
GLY A 109
 None
 0.98A 1zz1C-1azwA:
undetectable		 1zz1C-1azwA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		4 / 6 HIS A  41
TYR A 233
ARG A  69
GLY A  70
 None
 1.43A 2i30A-1azwA:
0.0		 2i30A-1azwA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		3 / 3 THR A 114
ASP A 266
SER A 289
 None
 0.72A 2nxeA-1azwA:
2.2		 2nxeA-1azwA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		3 / 3 THR A 114
ASP A 266
SER A 289
 None
 0.74A 2nxeB-1azwA:
2.2		 2nxeB-1azwA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		4 / 6 GLY A 112
HIS A 294
HIS A 262
CYH A 269
 None
 1.37A 3ai8B-1azwA:
0.0		 3ai8B-1azwA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		4 / 6 GLY A  42
GLY A  43
SER A 110
HIS A 294
 None
 0.83A 3o9mB-1azwA:
12.8		 3o9mB-1azwA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 GLY A 109
GLY A 112
LEU A 115
ALA A 296
LEU A 305
 None
 1.18A 3vywA-1azwA:
undetectable		 3vywA-1azwA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 GLY A 109
GLY A 112
LEU A 115
ALA A 296
LEU A 305
 None
 1.18A 3vywB-1azwA:
undetectable		 3vywB-1azwA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 GLY A 109
GLY A 112
LEU A 115
ALA A 296
LEU A 305
 None
 1.18A 3vywD-1azwA:
undetectable		 3vywD-1azwA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A   4
VAL A 302
ARG A 133
PHE A 213
GLY A  43
 None
 1.30A 4q15A-1azwA:
undetectable		 4q15A-1azwA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A   4
VAL A 302
ARG A 133
PHE A 213
GLY A  43
 None
 1.31A 4q15B-1azwA:
undetectable		 4q15B-1azwA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_1
(BIFUNCTIONAL AAC/APH)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 GLY A  70
HIS A 232
TYR A 233
ASP A  87
ASP A  19
 None
 1.16A 4qc6B-1azwA:
1.3		 4qc6B-1azwA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 VAL A 268
GLU A 230
GLY A  43
ILE A 229
SER A  71
 None
 1.44A 4xudA-1azwA:
2.9		 4xudA-1azwA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A   4
VAL A 302
ARG A 133
PHE A 213
GLY A  43
 None
 1.25A 4ydqA-1azwA:
undetectable		 4ydqA-1azwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 8 LEU A 130
ALA A 116
LEU A 132
LEU A 277
ALA A 120
 None
 0.82A 4z90A-1azwA:
0.0
4z90B-1azwA:
0.0
4z90C-1azwA:
0.0
4z90D-1azwA:
0.0
4z90E-1azwA:
0.0		 4z90A-1azwA:
21.94
4z90B-1azwA:
21.94
4z90C-1azwA:
21.94
4z90D-1azwA:
21.94
4z90E-1azwA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		4 / 7 THR A  85
LEU A  88
THR A 114
LEU A 115
 None
 0.77A 4z90A-1azwA:
0.0
4z90B-1azwA:
0.0
4z90C-1azwA:
0.0
4z90D-1azwA:
0.0
4z90E-1azwA:
0.0		 4z90A-1azwA:
21.94
4z90B-1azwA:
21.94
4z90C-1azwA:
21.94
4z90D-1azwA:
21.94
4z90E-1azwA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		3 / 3 ARG A  53
TYR A  25
GLU A  27
 None
 0.59A 4zzbE-1azwA:
undetectable		 4zzbE-1azwA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A   4
VAL A 302
ARG A 133
PHE A 213
GLY A  43
 None
 1.28A 5f9zA-1azwA:
undetectable		 5f9zA-1azwA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A   4
VAL A 302
ARG A 133
PHE A 213
GLY A  43
 None
 1.34A 5f9zB-1azwA:
undetectable		 5f9zB-1azwA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 PHE A  55
ARG A  73
TYR A  61
THR A 309
GLU A  27
 None
 1.46A 5v1tA-1azwA:
undetectable		 5v1tA-1azwA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 12 LEU A   4
VAL A 302
ARG A 133
PHE A 213
GLY A  43
 None
 1.34A 5xiqD-1azwA:
undetectable		 5xiqD-1azwA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 1azw PROLINE
IMINOPEPTIDASE
(Xanthomonas
citri) 		5 / 7 GLY A 109
GLY A  43
PRO A  44
GLY A  45
GLY A  46
 None
 0.87A 6ag0A-1azwA:
undetectable		 6ag0A-1azwA:
10.39