SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1azz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 8 PHE A 228
THR A 229
ASP A 102
HIS A  57
 None
 0.75A 1ei6C-1azzA:
undetectable		 1ei6C-1azzA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ILE A 118
ALA A  70
ILE A  52
LEU A 108
PRO A 109
 None
 1.10A 1jolB-1azzA:
undetectable		 1jolB-1azzA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 LEU A 155
GLU A  77
GLY A  69
ALA A 117
ALA A 116
 None
 1.15A 2br4D-1azzA:
undetectable		 2br4D-1azzA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 LEU A 155
GLU A  77
GLY A  69
ALA A 117
ALA A 116
 None
 1.13A 2br4E-1azzA:
undetectable		 2br4E-1azzA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.90A 2f8gB-1azzA:
undetectable		 2f8gB-1azzA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.94A 2ienB-1azzA:
undetectable		 2ienB-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  64
ILE A  35
GLY A  61
VAL A 105
ILE A 106
 None
 0.87A 2o4lA-1azzA:
undetectable		 2o4lA-1azzA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 11 ALA A  32
VAL A  81
GLY A  44
ILE A  52
VAL A 112
 None
 1.21A 2uxpB-1azzA:
undetectable		 2uxpB-1azzA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 GLY A 189
GLY A 188
ASP A 159
THR A 137
ILE A  16
 None
 1.02A 2wa2A-1azzA:
undetectable		 2wa2A-1azzA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 1azz COLLAGENASE
(Leptuca
pugilator) 		3 / 3 SER A  45
HIS A  71
ASP A 153
 None
 0.76A 2wa2B-1azzA:
undetectable		 2wa2B-1azzA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 8 GLY A 140
THR A 139
PHE A  41
GLY A  43
 None
 0.75A 3aruA-1azzA:
undetectable		 3aruA-1azzA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.88A 3cywA-1azzA:
undetectable		 3cywA-1azzA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.97A 3d1zA-1azzA:
undetectable		 3d1zA-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 1.09A 3d20A-1azzA:
undetectable		 3d20A-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 11 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 1.04A 3ektD-1azzA:
undetectable		 3ektD-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 8 GLY A  61
ALA A  61
ASP A  60
THR A  54
 None
 0.66A 3el0A-1azzA:
undetectable		 3el0A-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 1.03A 3mwsA-1azzA:
undetectable		 3mwsA-1azzA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 1.05A 3ndwA-1azzA:
undetectable		 3ndwA-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.99A 3nu3A-1azzA:
undetectable		 3nu3A-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		6 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
VAL A  90
ILE A  35
 None
 1.41A 3s54A-1azzA:
undetectable		 3s54A-1azzA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 7 ASN A  72
ILE A  73
PHE A  34
GLN A  80
 None
 1.14A 3tvxB-1azzA:
undetectable		 3tvxB-1azzA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 8 ILE A 103
ASP A 102
ILE A 212
GLY A  44
 None
 0.80A 4ac9C-1azzA:
2.3		 4ac9C-1azzA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 7 ASP A 159
GLY A 189
THR A 190
ILE A  16
 None
 0.84A 4acaC-1azzA:
3.0		 4acaC-1azzA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 10 LEU A  53
ILE A 106
ILE A 212
GLY A 196
GLY A  43
 None
 0.96A 4fakA-1azzA:
undetectable		 4fakA-1azzA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 10 LEU A  53
ILE A 106
ILE A 212
GLY A 197
GLY A  43
 None
 0.93A 4fakA-1azzA:
undetectable		 4fakA-1azzA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 7 ASN A  25
GLY A  69
GLN A  80
ILE A  73
PHE A  34
 None
 1.49A 4fglC-1azzA:
undetectable		 4fglC-1azzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 8 ILE A  52
LEU A  33
ILE A 212
GLY A 140
 None
 0.85A 4hb8A-1azzA:
undetectable		 4hb8A-1azzA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.96A 4jecB-1azzA:
undetectable		 4jecB-1azzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1azz COLLAGENASE
(Leptuca
pugilator) 		4 / 5 LEU A 123
PRO A 124
LEU A 235
ILE A 238
 None
 1.06A 4klrA-1azzA:
undetectable		 4klrA-1azzA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.97A 4njvA-1azzA:
undetectable		 4njvA-1azzA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.98A 4njvD-1azzA:
undetectable		 4njvD-1azzA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 GLY A 197
THR A 190
LEU A  33
ILE A 212
ASP A 102
 None
 1.28A 4pghB-1azzA:
undetectable		 4pghB-1azzA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 11 GLY A  61
ALA A  61
ASP A  60
THR A  89
THR A  54
 None
 0.84A 4qgiA-1azzA:
undetectable		 4qgiA-1azzA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 9 PRO A 198
LEU A  33
ILE A 212
LEU A  53
THR A  54
 None
 1.22A 4x3mB-1azzA:
undetectable		 4x3mB-1azzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		6 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
VAL A  90
ILE A  35
 None
 1.32A 5e5kA-1azzA:
undetectable		 5e5kA-1azzA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ALA A  55
GLY A  44
ASP A 102
ILE A  99
GLY A 179
 None
 1.26A 5wwsB-1azzA:
undetectable		 5wwsB-1azzA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 VAL A 158
VAL A 160
GLY A 216
THR A 229
GLY A 211
 None
 1.17A 6brdC-1azzA:
undetectable		 6brdC-1azzA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.95A 6dh3B-1azzA:
undetectable		 6dh3B-1azzA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 ASP A  37
GLY A  61
ALA A  61
ASP A  60
ILE A  35
 None
 0.95A 6dh6B-1azzA:
0.0		 6dh6B-1azzA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 THR A 213
ASP A 194
SER A  45
ASN A 200
VAL A 158
 None
 1.48A 6h7lA-1azzA:
undetectable		 6h7lA-1azzA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1azz COLLAGENASE
(Leptuca
pugilator) 		5 / 12 THR A 213
ASP A 194
SER A  45
ASN A 200
VAL A 158
 None
 1.48A 6h7lB-1azzA:
undetectable		 6h7lB-1azzA:
18.06