SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_C_FUAC701_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	1b0b	HEMOGLOBIN (Phacoides pectinatus)	5 / 12	PHE A 92 PHE A 29 LEU A 32 VAL A 112 VAL A 39	HEM A 144 (-4.4A) CYN A 145 (-4.4A) None None HEM A 144 ( 3.6A)	1.15A	1q23C-1b0bA: undetectable	1q23C-1b0bA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_L_FUAL710_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	1b0b	HEMOGLOBIN (Phacoides pectinatus)	5 / 11	PHE A 92 PHE A 29 LEU A 32 VAL A 112 VAL A 39	HEM A 144 (-4.4A) CYN A 145 (-4.4A) None None HEM A 144 ( 3.6A)	1.20A	1q23L-1b0bA: undetectable	1q23L-1b0bA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B2R_A_VDNA1_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	1b0b	HEMOGLOBIN (Phacoides pectinatus)	5 / 12	ALA A 108 VAL A 39 PHE A 43 MET A 30 PHE A 28	None HEM A 144 ( 3.6A) HEM A 144 ( 3.8A) None None	1.09A	3b2rA-1b0bA: undetectable	3b2rA-1b0bA: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_ACTA810_0 (GEPHYRIN)	1b0b	HEMOGLOBIN (Phacoides pectinatus)	3 / 3	LEU A 46 SER A 44 PHE A 43	HEM A 144 ( 3.9A) None HEM A 144 ( 3.8A)	0.60A	6fgcA-1b0bA: undetectable	6fgcA-1b0bA: 16.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Q23_C_FUAC701_2","CHLORAMPHENICOL ACETYLTRANSFERASE","1b0b","HEMOGLOBIN","Phacoides pectinatus",5,"PHE A  92;PHE A  29;LEU A  32;VAL A 112;VAL A  39","HEM A 144 (-4.4A);CYN A 145 (-4.4A);None;None;HEM A 144 ( 3.6A)","1.15A","1q23C-1b0bA:undetectable","1q23C-1b0bA:23.44"],["1Q23_L_FUAL710_2","CHLORAMPHENICOL ACETYLTRANSFERASE","1b0b","HEMOGLOBIN","Phacoides pectinatus",5,"PHE A  92;PHE A  29;LEU A  32;VAL A 112;VAL A  39","HEM A 144 (-4.4A);CYN A 145 (-4.4A);None;None;HEM A 144 ( 3.6A)","1.20A","1q23L-1b0bA:undetectable","1q23L-1b0bA:23.44"],["3B2R_A_VDNA1_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","1b0b","HEMOGLOBIN","Phacoides pectinatus",5,"ALA A 108;VAL A  39;PHE A  43;MET A  30;PHE A  28","None;HEM A 144 ( 3.6A);HEM A 144 ( 3.8A);None;None","1.09A","3b2rA-1b0bA:undetectable","3b2rA-1b0bA:19.08"],["6FGC_A_ACTA810_0","GEPHYRIN","1b0b","HEMOGLOBIN","Phacoides pectinatus",3,"LEU A  46;SER A  44;PHE A  43","HEM A 144 ( 3.9A);None;HEM A 144 ( 3.8A)","0.60A","6fgcA-1b0bA:undetectable","6fgcA-1b0bA:16.43"]]