SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 GLN A  72
GLY A 144
CYH A 421
GLY A 392
 FLC  A 756 (-3.6A)
None
SF4  A 755 (-2.3A)
None
 0.70A 1f5lA-1b0kA:
undetectable		 1f5lA-1b0kA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 HIS A 147
HIS A 167
THR A 168
SER A 643
 None
O  A1100 ( 3.9A)
None
FLC  A 756 (-2.8A)
 0.83A 1gtfN-1b0kA:
undetectable
1gtfO-1b0kA:
undetectable		 1gtfN-1b0kA:
8.16
1gtfO-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 9 GLY A 353
GLY A 414
ILE A 415
PRO A 391
ILE A 355
 None
 1.10A 1hxwA-1b0kA:
undetectable		 1hxwA-1b0kA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 8 GLY A 513
GLY A 144
SER A 393
ARG A 397
GLY A 142
 None
 1.41A 1jhqA-1b0kA:
undetectable		 1jhqA-1b0kA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 HIS A 646
ILE A 586
VAL A 123
SER A 535
 None
 1.06A 1kb9A-1b0kA:
0.0
1kb9C-1b0kA:
0.0
1kb9D-1b0kA:
0.0
1kb9E-1b0kA:
0.0		 1kb9A-1b0kA:
19.68
1kb9C-1b0kA:
19.68
1kb9D-1b0kA:
15.86
1kb9E-1b0kA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 LEU A  47
LEU A 160
ALA A  70
VAL A  43
LEU A 197
 None
 1.43A 1kt6A-1b0kA:
0.0		 1kt6A-1b0kA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 7 ILE A  97
GLY A 131
PHE A 126
ASN A 125
 None
 0.88A 1oniG-1b0kA:
0.0
1oniI-1b0kA:
0.0		 1oniG-1b0kA:
13.12
1oniI-1b0kA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 VAL A 123
ASN A 585
ILE A 586
GLY A 581
LEU A 102
 None
 0.71A 1r9oA-1b0kA:
undetectable		 1r9oA-1b0kA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		3 / 3 ILE A 715
ILE A 725
THR A 721
 None
 0.54A 1rg7A-1b0kA:
undetectable		 1rg7A-1b0kA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 7 GLN A  82
ALA A 744
PHE A 544
GLU A 645
 None
 1.33A 1t9wA-1b0kA:
0.0		 1t9wA-1b0kA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 GLY A 180
SER A 643
ASP A 100
THR A 168
HIS A 147
 None
FLC  A 756 (-2.8A)
None
None
None
 1.40A 2hmaA-1b0kA:
undetectable		 2hmaA-1b0kA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 9 PHE A 387
ARG A 410
ALA A 406
LEU A 409
GLY A 414
 None
 1.44A 2wscA-1b0kA:
0.0		 2wscA-1b0kA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 9 PHE A 387
ARG A 410
ALA A 406
LEU A 409
GLY A 414
 None
 1.43A 2wseA-1b0kA:
0.0		 2wseA-1b0kA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 9 PHE A 387
ARG A 410
ALA A 406
LEU A 409
GLY A 414
 None
 1.45A 2wsfA-1b0kA:
0.0		 2wsfA-1b0kA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		6 / 12 ALA A  79
GLY A 163
GLY A 182
GLY A 183
ILE A 150
ALA A  70
 None
 1.36A 3douA-1b0kA:
undetectable		 3douA-1b0kA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 10 VAL A 632
ALA A 658
ILE A 699
ILE A 715
ILE A 633
 None
 1.14A 3hbbA-1b0kA:
undetectable		 3hbbA-1b0kA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 10 VAL A 632
ALA A 658
ILE A 699
ILE A 715
ILE A 633
 None
 1.24A 3hbbD-1b0kA:
0.0		 3hbbD-1b0kA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ILE A 248
VAL A 205
ILE A 263
VAL A 224
VAL A 220
 None
 1.21A 3iw1A-1b0kA:
0.0		 3iw1A-1b0kA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		3 / 3 GLU A 723
ASP A 695
ASP A 687
 None
 0.77A 3jb2A-1b0kA:
0.0		 3jb2A-1b0kA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 TYR A 272
GLY A 171
ALA A 155
ILE A 288
 None
 0.70A 3jusB-1b0kA:
0.0		 3jusB-1b0kA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLU A 262
GLY A 180
ALA A  74
ASP A 568
ARG A 580
 None
None
FLC  A 756 ( 3.8A)
FLC  A 756 ( 4.7A)
FLC  A 756 (-3.3A)
 1.28A 3jzjA-1b0kA:
0.0		 3jzjA-1b0kA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 9 PHE A 387
ARG A 410
ALA A 406
LEU A 409
GLY A 414
 None
 1.45A 3lw5A-1b0kA:
0.0		 3lw5A-1b0kA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 HIS A 668
TYR A 638
ILE A 570
GLY A 593
ALA A 594
 None
 1.21A 3n8xA-1b0kA:
0.0		 3n8xA-1b0kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 LEU A 127
HIS A 646
LEU A 538
ILE A 150
GLY A 163
 None
 1.05A 3ozwB-1b0kA:
undetectable		 3ozwB-1b0kA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 7 LEU A 102
ASP A 100
ALA A 420
ASP A  73
 None
 1.01A 3rodD-1b0kA:
0.7		 3rodD-1b0kA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		6 / 12 ALA A 225
ASP A 329
GLY A 233
ILE A 203
ILE A 256
ILE A 221
 None
 1.10A 3s54B-1b0kA:
undetectable		 3s54B-1b0kA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 VAL A 159
GLY A 176
VAL A  43
ILE A 146
ALA A  70
 None
 0.90A 3sufD-1b0kA:
undetectable		 3sufD-1b0kA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 353
GLY A 414
ILE A 415
PRO A 391
ILE A 355
 None
 1.04A 3tkgC-1b0kA:
undetectable		 3tkgC-1b0kA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 GLY A 353
VAL A 412
GLY A 413
GLY A 414
ILE A 415
 None
 0.80A 3ufnA-1b0kA:
undetectable		 3ufnA-1b0kA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 6 GLY A 641
GLU A 640
ASP A 568
ASN A 448
 None
None
FLC  A 756 ( 4.7A)
None
 0.91A 3vywC-1b0kA:
undetectable		 3vywC-1b0kA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 6 PRO A 243
GLY A 244
LEU A 315
ASN A 314
GLU A 312
 None
 1.44A 3zqtA-1b0kA:
0.0		 3zqtA-1b0kA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 6 PRO A 325
GLY A 324
ASN A 323
GLU A 344
 None
 0.98A 3zqtA-1b0kA:
0.0		 3zqtA-1b0kA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ILE A  42
THR A 266
LEU A  64
LEU A 197
ILE A 237
 None
 1.06A 4c9lA-1b0kA:
0.0		 4c9lA-1b0kA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ILE A  42
THR A 266
LEU A  64
LEU A 197
ILE A 237
 None
 1.04A 4c9oA-1b0kA:
0.0		 4c9oA-1b0kA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ILE A  42
THR A 266
LEU A  64
LEU A 197
ILE A 237
 None
 1.05A 4c9oB-1b0kA:
0.0		 4c9oB-1b0kA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ARG A 644
GLY A 641
ALA A 642
SER A 166
GLY A 180
 FLC  A 756 (-4.3A)
None
FLC  A 756 (-3.0A)
FLC  A 756 (-2.6A)
None
 0.91A 4e1gB-1b0kA:
0.0		 4e1gB-1b0kA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 175
GLY A 176
SER A 249
GLY A 244
LEU A 207
 None
 1.02A 4fp9A-1b0kA:
undetectable		 4fp9A-1b0kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 175
GLY A 176
SER A 249
GLY A 244
LEU A 207
 None
 1.03A 4fp9C-1b0kA:
undetectable		 4fp9C-1b0kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 175
GLY A 176
SER A 249
GLY A 244
LEU A 207
 None
 1.03A 4fp9D-1b0kA:
undetectable		 4fp9D-1b0kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 175
GLY A 176
SER A 249
GLY A 244
LEU A 207
 None
 1.03A 4fp9F-1b0kA:
undetectable		 4fp9F-1b0kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 175
GLY A 176
SER A 249
GLY A 244
LEU A 207
 None
 1.09A 4fzvA-1b0kA:
undetectable		 4fzvA-1b0kA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 5 GLY A 676
SER A 743
ALA A 744
PHE A 739
 None
 1.07A 4m93B-1b0kA:
undetectable
4m93C-1b0kA:
undetectable		 4m93B-1b0kA:
14.89
4m93C-1b0kA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ASP A 454
GLY A 451
ALA A 461
PHE A 326
GLY A 436
 None
 0.93A 4n09A-1b0kA:
undetectable		 4n09A-1b0kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ASP A 454
GLY A 451
ALA A 461
PHE A 326
GLY A 436
 None
 0.92A 4n09B-1b0kA:
undetectable		 4n09B-1b0kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ASP A 454
GLY A 451
ALA A 461
PHE A 326
GLY A 436
 None
 0.91A 4n09C-1b0kA:
undetectable		 4n09C-1b0kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 ASP A 454
GLY A 451
ALA A 461
PHE A 326
GLY A 436
 None
 0.96A 4n09D-1b0kA:
undetectable		 4n09D-1b0kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 GLY A 353
GLY A 414
ILE A 415
PRO A 391
ILE A 355
 None
 1.02A 4njvB-1b0kA:
undetectable		 4njvB-1b0kA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 LEU A 174
GLY A 175
ARG A 285
THR A 267
ILE A 237
 None
 1.31A 4oktA-1b0kA:
undetectable		 4oktA-1b0kA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 LEU A 174
GLY A 175
ARG A 285
THR A 267
ILE A 237
 None
 1.32A 4okwA-1b0kA:
0.0		 4okwA-1b0kA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 549
ASP A 548
PHE A 739
GLY A 742
ASP A 545
 None
 1.00A 4pevB-1b0kA:
0.0		 4pevB-1b0kA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 108
GLY A 109
ASP A 112
ASP A 429
ILE A 415
 None
 0.99A 4pghD-1b0kA:
undetectable		 4pghD-1b0kA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 176
ILE A 179
GLY A 163
ILE A 177
ILE A 150
 None
 1.01A 4q5mA-1b0kA:
undetectable		 4q5mA-1b0kA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 ALA A  79
ILE A 146
GLY A 163
VAL A  93
 None
 0.62A 4r20A-1b0kA:
0.0		 4r20A-1b0kA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 5 PHE A  83
SER A 647
HIS A 668
ASP A 185
 None
 1.41A 4rzvB-1b0kA:
0.0		 4rzvB-1b0kA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		3 / 3 SER A 643
ASP A  67
ASP A 185
 FLC  A 756 (-2.8A)
None
None
 0.74A 4uckA-1b0kA:
undetectable		 4uckA-1b0kA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 LEU A 228
GLY A 204
ALA A 265
SER A 268
PHE A 270
 None
 1.30A 4wnuC-1b0kA:
0.0		 4wnuC-1b0kA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 ALA A 573
HIS A 101
ARG A 644
ARG A 580
 None
FLC  A 756 ( 3.8A)
FLC  A 756 (-4.3A)
FLC  A 756 (-3.3A)
 1.20A 5db5A-1b0kA:
undetectable
5db5B-1b0kA:
undetectable		 5db5A-1b0kA:
20.08
5db5B-1b0kA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 ALA A 642
ARG A 452
HIS A 646
THR A  75
 FLC  A 756 (-3.0A)
FLC  A 756 (-3.0A)
None
FLC  A 756 ( 4.4A)
 1.26A 5db5A-1b0kA:
undetectable
5db5B-1b0kA:
undetectable		 5db5A-1b0kA:
20.08
5db5B-1b0kA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 SER A 643
HIS A 147
HIS A 167
THR A 168
 FLC  A 756 (-2.8A)
None
O  A1100 ( 3.9A)
None
 0.84A 5eevL-1b0kA:
undetectable
5eevV-1b0kA:
undetectable		 5eevL-1b0kA:
8.16
5eevV-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 SER A 643
HIS A 147
HIS A 167
THR A 168
 FLC  A 756 (-2.8A)
None
O  A1100 ( 3.9A)
None
 0.84A 5eewL-1b0kA:
0.0
5eewV-1b0kA:
undetectable		 5eewL-1b0kA:
8.16
5eewV-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 SER A 643
HIS A 147
HIS A 167
THR A 168
 FLC  A 756 (-2.8A)
None
O  A1100 ( 3.9A)
None
 0.84A 5eezL-1b0kA:
undetectable
5eezV-1b0kA:
undetectable		 5eezL-1b0kA:
8.16
5eezV-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 SER A 643
HIS A 147
HIS A 167
THR A 168
 FLC  A 756 (-2.8A)
None
O  A1100 ( 3.9A)
None
 0.84A 5ef1L-1b0kA:
undetectable
5ef1V-1b0kA:
undetectable		 5ef1L-1b0kA:
8.16
5ef1V-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 SER A 643
HIS A 147
HIS A 167
THR A 168
 FLC  A 756 (-2.8A)
None
O  A1100 ( 3.9A)
None
 0.84A 5ef2L-1b0kA:
undetectable
5ef2V-1b0kA:
undetectable		 5ef2L-1b0kA:
8.16
5ef2V-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 SER A 643
HIS A 147
HIS A 167
THR A 168
 FLC  A 756 (-2.8A)
None
O  A1100 ( 3.9A)
None
 0.84A 5ef3L-1b0kA:
0.0
5ef3V-1b0kA:
0.0		 5ef3L-1b0kA:
8.16
5ef3V-1b0kA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 GLY A 182
ILE A 256
GLY A 252
GLY A 173
THR A 164
 None
 1.04A 5eqbA-1b0kA:
0.0		 5eqbA-1b0kA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 ILE A  42
TRP A 195
LEU A  21
VAL A 269
CYH A 178
 None
 1.18A 5ji0A-1b0kA:
undetectable		 5ji0A-1b0kA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 PHE A 544
GLN A 675
HIS A 646
LEU A 590
LEU A 541
 None
 1.29A 5ji0D-1b0kA:
undetectable		 5ji0D-1b0kA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 9 SER A 444
SER A 216
ASP A 219
PRO A 320
SER A 369
 None
 1.45A 5l1fB-1b0kA:
1.2		 5l1fB-1b0kA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		3 / 3 THR A 661
PRO A 651
ARG A 652
 None
 0.86A 5nd7B-1b0kA:
undetectable		 5nd7B-1b0kA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 10 PHE A 387
ARG A 410
ILE A 400
ALA A 406
LEU A 409
 None
 1.44A 5oy0b-1b0kA:
0.0		 5oy0b-1b0kA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 12 VAL A 202
LEU A  62
VAL A  43
HIS A  46
LEU A  47
 None
 1.30A 5ubbA-1b0kA:
undetectable		 5ubbA-1b0kA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 8 LEU A  62
TYR A  44
GLU A  40
THR A  60
 None
 1.05A 6c71B-1b0kA:
0.0		 6c71B-1b0kA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		3 / 3 ARG A   2
ARG A  17
ASP A  19
 None
 0.90A 6d8pA-1b0kA:
0.0		 6d8pA-1b0kA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 6 ASP A 584
ARG A 621
GLN A 539
GLN A 536
 None
 1.32A 6g31B-1b0kA:
undetectable		 6g31B-1b0kA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 7 ASP A 584
ARG A 621
GLN A 539
GLN A 536
 None
 1.19A 6g31G-1b0kA:
undetectable		 6g31G-1b0kA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		4 / 6 ASP A 584
ARG A 621
GLN A 539
GLN A 536
 None
 1.35A 6g31L-1b0kA:
undetectable		 6g31L-1b0kA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 1b0k PROTEIN (ACONITASE)
(Sus
scrofa) 		5 / 11 ASN A 419
THR A 283
PHE A 510
THR A 399
ILE A 400
 None
 1.45A 6hcoA-1b0kA:
0.0
6hcoB-1b0kA:
0.0		 6hcoA-1b0kA:
21.76
6hcoB-1b0kA:
21.76