SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_A_TFPA204_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1b0n	PROTEIN (SINI PROTEIN) PROTEIN (SINR PROTEIN) (Bacillus subtilis)	4 / 7	PHE A 98 PHE A 95 MET B 19 VAL B 16	None	1.12A	1wrlA-1b0nA: undetectable 1wrlB-1b0nA: undetectable	1wrlA-1b0nA: 23.01 1wrlB-1b0nA: 23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y0X_X_T44X500_1 (THYROID HORMONE RECEPTOR BETA-1)	1b0n	PROTEIN (SINI PROTEIN) PROTEIN (SINR PROTEIN) (Bacillus subtilis)	5 / 12	ILE B 27 ALA B 25 MET B 19 PHE A 98 PHE A 95	None	1.36A	1y0xX-1b0nB: undetectable	1y0xX-1b0nB: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8I_A_RO7A1_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	1b0n	PROTEIN (SINR PROTEIN) (Bacillus subtilis)	4 / 7	GLN A 45 LEU A 61 VAL A 53 LEU A 31	None	0.95A	3g8iA-1b0nA: undetectable	3g8iA-1b0nA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K9F_H_LFXH0_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B)	1b0n	PROTEIN (SINR PROTEIN) (Bacillus subtilis)	4 / 6	SER A 43 GLY A 25 GLU A 19 GLU A 22	None	1.11A	3k9fA-1b0nA: 0.0 3k9fB-1b0nA: 0.0 3k9fD-1b0nA: undetectable	3k9fA-1b0nA: 13.06 3k9fB-1b0nA: 13.06 3k9fD-1b0nA: 17.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_A_TFPA204_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1b0n","PROTEIN (SINI PROTEIN);PROTEIN (SINR PROTEIN)","Bacillus subtilis",4,"PHE A  98;PHE A  95;MET B  19;VAL B  16","None","1.12A","1wrlA-1b0nA:undetectable;1wrlB-1b0nA:undetectable","1wrlA-1b0nA:23.01;1wrlB-1b0nA:23.01"],["1Y0X_X_T44X500_1","THYROID HORMONE RECEPTOR BETA-1","1b0n","PROTEIN (SINI PROTEIN);PROTEIN (SINR PROTEIN)","Bacillus subtilis",5,"ILE B  27;ALA B  25;MET B  19;PHE A  98;PHE A  95","None","1.36A","1y0xX-1b0nB:undetectable","1y0xX-1b0nB:14.71"],["3G8I_A_RO7A1_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA","1b0n","PROTEIN (SINR PROTEIN)","Bacillus subtilis",4,"GLN A  45;LEU A  61;VAL A  53;LEU A  31","None","0.95A","3g8iA-1b0nA:undetectable","3g8iA-1b0nA:19.37"],["3K9F_H_LFXH0_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B","1b0n","PROTEIN (SINR PROTEIN)","Bacillus subtilis",4,"SER A  43;GLY A  25;GLU A  19;GLU A  22","None","1.11A","3k9fA-1b0nA:0.0;3k9fB-1b0nA:0.0;3k9fD-1b0nA:undetectable","3k9fA-1b0nA:13.06;3k9fB-1b0nA:13.06;3k9fD-1b0nA:17.47"]]