SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		5 / 8 VAL A 174
VAL A 207
SER A  36
ILE A 224
LEU A  49
 None
 1.37A 1igxA-1b0uA:
0.0		 1igxA-1b0uA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		5 / 12 VAL A 114
THR A  96
LEU A 175
VAL A 140
PHE A 177
 None
 1.28A 2jn3A-1b0uA:
undetectable		 2jn3A-1b0uA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		5 / 12 LEU A  91
GLY A  61
LEU A  12
VAL A  65
ILE A  70
 None
 0.94A 3em6B-1b0uA:
undetectable		 3em6B-1b0uA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		4 / 7 LEU A 199
LEU A  27
VAL A 208
LEU A  91
 None
 0.94A 3g8iA-1b0uA:
undetectable		 3g8iA-1b0uA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		4 / 6 LEU A  49
SER A  46
PHE A  48
ILE A  37
 None
ATP  A 301 (-3.1A)
None
None
 0.99A 3ko0B-1b0uA:
0.7		 3ko0B-1b0uA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		3 / 3 GLU A 232
PHE A 225
GLN A 228
 None
 0.95A 3r55A-1b0uA:
0.0		 3r55A-1b0uA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		5 / 12 LEU A  22
PHE A  48
LEU A   7
ILE A  70
LEU A  91
 None
 1.31A 5ienA-1b0uA:
0.0		 5ienA-1b0uA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		4 / 8 VAL A 207
LEU A 176
ILE A  63
VAL A  65
 None
 0.65A 5nujA-1b0uA:
0.0		 5nujA-1b0uA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 1b0u HISTIDINE PERMEASE
(Salmonella
enterica) 		4 / 6 LEU A  80
GLY A  78
ARG A  74
ARG A  15
 None
 1.14A 6gtqB-1b0uA:
0.0
6gtqD-1b0uA:
undetectable		 6gtqB-1b0uA:
21.64
6gtqD-1b0uA:
14.71