SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 8 LEU A 212
ALA A  87
GLY A  79
ILE A  78
PHE A 193
 None
 1.10A 1d4sB-1b0zA:
undetectable		 1d4sB-1b0zA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 6 LEU A 376
LEU A 365
LEU A  19
LEU A  22
 None
 0.73A 1errA-1b0zA:
0.2		 1errA-1b0zA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A 123
LEU A 132
ALA A  74
PHE A 150
ILE A 134
 None
 0.99A 1g5yC-1b0zA:
undetectable		 1g5yC-1b0zA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  36
ILE A 199
TRP A  46
 None
 0.99A 1m8eB-1b0zA:
0.0		 1m8eB-1b0zA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  36
ILE A 199
TRP A  46
 None
 0.96A 1nodB-1b0zA:
0.0		 1nodB-1b0zA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 169
TYR A 161
LYS A 160
 None
 0.98A 1uujB-1b0zA:
0.0		 1uujB-1b0zA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A 127
PRO A 213
ILE A 134
LEU A 132
 None
 1.04A 1ya4B-1b0zA:
0.8		 1ya4B-1b0zA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 5 LEU A 206
GLY A  45
TRP A  46
ASP A  48
 None
 0.95A 1zwpA-1b0zA:
0.0		 1zwpA-1b0zA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 10 GLY A 210
LEU A 211
LEU A 212
ILE A  61
PHE A 193
 None
 0.99A 2f8dA-1b0zA:
undetectable		 2f8dA-1b0zA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 10 GLY A 210
LEU A 211
LEU A 212
ILE A  61
PHE A 193
 None
 0.99A 2f8dB-1b0zA:
undetectable		 2f8dB-1b0zA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  36
ILE A 199
TRP A  46
 None
 0.99A 2nodB-1b0zA:
undetectable		 2nodB-1b0zA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 8 GLU A 128
LEU A 124
LEU A 123
VAL A  76
ILE A  78
 None
 1.37A 2uxpA-1b0zA:
0.0		 2uxpA-1b0zA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  36
ILE A 199
TRP A  46
 None
 0.94A 3e68A-1b0zA:
0.0		 3e68A-1b0zA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  36
ILE A 199
TRP A  46
 None
 0.94A 3e6tB-1b0zA:
0.0		 3e6tB-1b0zA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  36
ILE A 199
TRP A  46
 None
 1.05A 3nw2B-1b0zA:
0.0		 3nw2B-1b0zA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 7 TYR A 268
VAL A 266
PHE A 361
ILE A 377
 None
 0.93A 3zjqA-1b0zA:
undetectable		 3zjqA-1b0zA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 7 TYR A 268
VAL A 266
PHE A 361
ILE A 377
 None
 0.92A 3zjqB-1b0zA:
undetectable		 3zjqB-1b0zA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 272
VAL A 326
PHE A 395
MET A 391
LEU A 282
 None
 1.49A 4o8fB-1b0zA:
0.0		 4o8fB-1b0zA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 GLY A 200
GLN A 413
LYS A 139
 None
 0.97A 5imsB-1b0zA:
3.4		 5imsB-1b0zA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		3 / 3 LYS A 159
LEU A 127
ILE A 134
 None
 0.79A 5kc4A-1b0zA:
0.0		 5kc4A-1b0zA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A  40
GLY A  38
TRP A  46
MET A  32
PHE A  43
 None
 1.33A 5yf0A-1b0zA:
0.9		 5yf0A-1b0zA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 5 GLU A 321
VAL A 312
HIS A 306
THR A 364
 None
 1.18A 6dyoA-1b0zA:
0.8		 6dyoA-1b0zA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)
(Geobacillus
stearothermophil
us) 		4 / 8 ILE A 199
THR A 173
VAL A 172
SER A 140
 None
 0.98A 6fbvC-1b0zA:
0.0		 6fbvC-1b0zA:
17.55