SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b1y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 8 LEU A  84
VAL A  48
THR A 415
ASP A  51
 None
None
None
GLC  A 550 (-3.1A)
 1.15A 1dz9A-1b1yA:
0.0		 1dz9A-1b1yA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 7 HIS A 271
LEU A 133
ASP A 138
PHE A  90
 None
 1.12A 1ismB-1b1yA:
0.8		 1ismB-1b1yA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ASP A  99
HIS A  91
ASP A  51
 GLC  A 550 (-2.5A)
GLC  A 550 (-3.8A)
GLC  A 550 (-3.1A)
 0.76A 1nw5A-1b1yA:
undetectable		 1nw5A-1b1yA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 8 ARG A 274
ASN A 139
ASN A 267
ASP A 214
 None
 1.30A 1p6kB-1b1yA:
0.0		 1p6kB-1b1yA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 8 LEU A  84
VAL A  48
THR A 415
ASP A  51
 None
None
None
GLC  A 550 (-3.1A)
 1.15A 1uyuA-1b1yA:
undetectable		 1uyuA-1b1yA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 ILE A 294
ASN A 338
LEU A 411
VAL A 375
LEU A 365
 None
 1.20A 2bxfA-1b1yA:
undetectable		 2bxfA-1b1yA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 ILE A 294
ASN A 338
LEU A 411
VAL A 375
LEU A 365
 None
 1.15A 2bxfB-1b1yA:
undetectable		 2bxfB-1b1yA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 8 ILE A 392
LEU A 411
GLY A 413
PHE A 414
 None
 0.93A 2tsrB-1b1yA:
0.0		 2tsrB-1b1yA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 7 LEU A  76
LEU A  73
PHE A  27
PRO A  17
 None
 0.95A 2vq5B-1b1yA:
0.0		 2vq5B-1b1yA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 LEU A 365
LEU A 411
VAL A  10
ILE A 392
GLU A 343
 None
 1.22A 2weyA-1b1yA:
undetectable		 2weyA-1b1yA:
20.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		11 / 12 ALA A 182
GLU A 184
ARG A 186
TYR A 190
GLN A 192
TRP A 196
PHE A 198
GLY A 296
HIS A 298
THR A 340
MET A 344
 BGC  A 551 ( 3.5A)
BGC  A 551 (-4.1A)
None
None
BGC  A 552 (-3.6A)
None
BGC  A 552 (-4.0A)
None
BGC  A 552 (-4.1A)
BGC  A 551 (-3.1A)
BGC  A 552 ( 4.6A)
 0.75A 2xffA-1b1yA:
62.7		 2xffA-1b1yA:
97.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 ALA A  86
LEU A  84
MET A 452
GLY A 170
LEU A 167
 None
 1.02A 2yjaB-1b1yA:
0.1		 2yjaB-1b1yA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 GLN A 403
GLY A   7
GLY A 405
LEU A 443
ASN A 442
 None
 1.23A 2zw9B-1b1yA:
2.1		 2zw9B-1b1yA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 7 VAL A 361
ASP A 346
ILE A 392
ASN A 395
 None
 1.02A 3avpA-1b1yA:
0.0		 3avpA-1b1yA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 TRP A 299
VAL A 364
ARG A 370
 None
 0.92A 3b0wA-1b1yA:
0.0		 3b0wA-1b1yA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 11 LEU A  82
ALA A  43
VAL A  77
LEU A  16
HIS A 440
 None
 1.28A 3bszE-1b1yA:
0.0		 3bszE-1b1yA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 6 PRO A 181
LEU A 268
ALA A 312
PRO A 188
 None
 1.07A 3gv1A-1b1yA:
0.0
3gv1C-1b1yA:
0.0		 3gv1A-1b1yA:
15.90
3gv1C-1b1yA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 6 LEU A 268
ALA A 312
PRO A 188
PRO A 181
 None
 1.12A 3gv1A-1b1yA:
0.0
3gv1B-1b1yA:
0.0		 3gv1A-1b1yA:
15.90
3gv1B-1b1yA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ASN A 316
ASP A 321
ARG A 394
 None
 0.90A 3k13A-1b1yA:
6.8		 3k13A-1b1yA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ASN A 316
ASP A 321
ARG A 394
 None
 0.83A 3k13C-1b1yA:
7.3		 3k13C-1b1yA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 PHE A 260
TYR A 264
ALA A 233
THR A 243
ILE A 201
 None
 1.45A 3ld6B-1b1yA:
undetectable		 3ld6B-1b1yA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 MET A 156
LEU A 290
ILE A 275
ILE A 294
ALA A 295
 None
 1.18A 3nxuB-1b1yA:
0.0		 3nxuB-1b1yA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 6 ILE A 294
TRP A 196
ILE A 201
TRP A 299
 None
 1.12A 3weoA-1b1yA:
2.9		 3weoA-1b1yA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 6 GLY A 296
ALA A 182
GLU A 184
GLN A 349
 None
BGC  A 551 ( 3.5A)
BGC  A 551 (-4.1A)
None
 1.13A 4g0uA-1b1yA:
0.4		 4g0uA-1b1yA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ARG A 394
GLU A 358
ASN A 395
 None
 0.79A 4imaD-1b1yA:
13.8		 4imaD-1b1yA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ARG A 394
GLU A 358
ASN A 395
 None
 0.74A 4ip7D-1b1yA:
8.1		 4ip7D-1b1yA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1322_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 4 GLU A 378
THR A 415
GLU A 176
LYS A 293
 BGC  A 551 (-3.3A)
None
None
BGC  A 551 (-3.2A)
 1.28A 4mghA-1b1yA:
0.4		 4mghA-1b1yA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 ALA A  80
GLY A  81
LEU A  84
GLY A  47
VAL A  48
 None
 0.88A 4o33A-1b1yA:
2.1		 4o33A-1b1yA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ASP A 214
ASN A 139
SER A 265
 None
 0.82A 4obwA-1b1yA:
undetectable		 4obwA-1b1yA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 MET A 439
MET A 494
TYR A 389
 None
 1.11A 4p6xI-1b1yA:
0.0		 4p6xI-1b1yA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 TYR A 210
VAL A 137
LEU A 142
VAL A 112
GLY A 113
 None
 1.09A 4rrxA-1b1yA:
0.0		 4rrxA-1b1yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 TYR A 210
VAL A 137
LEU A 142
VAL A 112
GLY A 113
 None
 1.10A 4rrxB-1b1yA:
0.0		 4rrxB-1b1yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 GLY A 285
LEU A 455
ASP A 277
SER A 458
VAL A 177
 None
 1.17A 4wnwA-1b1yA:
0.0		 4wnwA-1b1yA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 11 ILE A  87
THR A 415
ASP A  51
GLU A 378
GLU A 184
 None
None
GLC  A 550 (-3.1A)
BGC  A 551 (-3.3A)
BGC  A 551 (-4.1A)
 1.42A 4xt7A-1b1yA:
undetectable		 4xt7A-1b1yA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 6 SER A 193
GLY A  94
ASN A  96
ILE A 130
 None
None
GLC  A 550 (-4.4A)
None
 1.04A 5j4nA-1b1yA:
0.0		 5j4nA-1b1yA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 12 LEU A 268
ALA A 307
VAL A 297
GLY A 296
ALA A 295
 None
 0.86A 5jw1A-1b1yA:
0.0		 5jw1A-1b1yA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		3 / 3 ARG A 186
PRO A 181
ASN A 129
 None
 0.95A 5jwaA-1b1yA:
0.6
5jwaH-1b1yA:
1.9		 5jwaA-1b1yA:
18.66
5jwaH-1b1yA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 8 PRO A 188
TYR A 121
SER A  89
SER A 193
 None
None
GLC  A 550 ( 4.2A)
None
 1.01A 5l1fA-1b1yA:
undetectable
5l1fB-1b1yA:
undetectable		 5l1fA-1b1yA:
20.10
5l1fB-1b1yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 9 ALA A  86
LEU A  84
MET A 452
GLY A 170
LEU A 167
 None
 1.03A 5wgqA-1b1yA:
0.2		 5wgqA-1b1yA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 5 TYR A 236
GLN A 235
GLY A 313
ILE A 205
 None
 1.42A 6debB-1b1yA:
undetectable		 6debB-1b1yA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		4 / 6 ASP A 174
GLN A  11
GLU A 176
THR A 340
 None
None
None
BGC  A 551 (-3.1A)
 1.27A 6djzA-1b1yA:
0.0		 6djzA-1b1yA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1b1y PROTEIN
(BETA-AMYLASE)
(Hordeum
vulgare) 		5 / 10 ALA A  86
LEU A  84
PHE A 166
VAL A  77
ALA A  20
 None
 1.40A 6h1lA-1b1yA:
0.0		 6h1lA-1b1yA:
21.97