SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		3 / 3 PHE A 109
VAL A 138
TRP A 141
 None
 0.80A 2cc8A-1b24A:
1.1		 2cc8A-1b24A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		3 / 3 PHE A 109
VAL A 138
TRP A 141
 None
 0.82A 2ccbA-1b24A:
1.0		 2ccbA-1b24A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		5 / 12 LEU A 142
ASN A 143
LEU A 145
GLY A 146
VAL A 174
 None
 1.16A 2oz7A-1b24A:
undetectable		 2oz7A-1b24A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		3 / 3 PHE A 109
VAL A 138
TRP A 141
 None
 0.80A 2vx9A-1b24A:
1.1		 2vx9A-1b24A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		5 / 12 ALA A 116
VAL A 160
TYR A 161
ILE A  18
THR A  41
 None
 1.14A 3dl9A-1b24A:
0.0		 3dl9A-1b24A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		4 / 5 HIS A 152
LEU A 142
LEU A 125
ASP A 169
 None
 1.27A 4aqlA-1b24A:
undetectable		 4aqlA-1b24A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		5 / 12 GLY A  22
GLY A  23
TYR A  25
ILE A  40
ILE A  19
 None
 1.17A 4fglA-1b24A:
undetectable
4fglB-1b24A:
undetectable		 4fglA-1b24A:
19.38
4fglB-1b24A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		3 / 3 ASN A 102
LEU A 145
PHE A 109
 None
 0.67A 5dsgA-1b24A:
0.0		 5dsgA-1b24A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		4 / 6 ASP A  21
ASP A 154
ARG A 126
ASN A 164
 None
 1.14A 5l6eA-1b24A:
undetectable		 5l6eA-1b24A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		3 / 3 TRP A 141
MET A 103
ASN A 102
 None
 1.44A 5uc1B-1b24A:
0.0		 5uc1B-1b24A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		3 / 3 TRP A 141
MET A 103
ASN A 102
 None
 1.45A 5uc1A-1b24A:
0.0		 5uc1A-1b24A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		4 / 6 ARG A 140
PHE A 109
ILE A 177
THR A 176
 None
 1.12A 5vceA-1b24A:
0.4		 5vceA-1b24A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		5 / 7 LEU A  95
ILE A  19
GLY A  16
LEU A 113
ILE A 151
 None
 0.88A 5vkqA-1b24A:
0.0
5vkqB-1b24A:
0.0		 5vkqA-1b24A:
7.51
5vkqB-1b24A:
7.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		5 / 8 LEU A  95
ILE A  19
GLY A  16
LEU A 113
ILE A 151
 None
 0.87A 5vkqB-1b24A:
0.0
5vkqC-1b24A:
0.0		 5vkqB-1b24A:
7.51
5vkqC-1b24A:
7.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1b24 PROTEIN (I-DMOI)
(Desulfurococcus
mucosus) 		5 / 9 LEU A  95
ILE A  19
GLY A  16
LEU A 113
ILE A 151
 None
 0.85A 5vkqC-1b24A:
0.0
5vkqD-1b24A:
0.0		 5vkqC-1b24A:
7.51
5vkqD-1b24A:
7.51