SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 10 TYR A 269
PRO A 268
ILE A 507
TYR A 498
GLY A 500
 None
 1.45A 13gsA-1b2hA:
undetectable		 13gsA-1b2hA:
17.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2H_A_ACTA518_0
(LYS-ORN-LYS
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 6 TYR A 245
ASN A 247
ASN A 366
HIS A 371
TRP A 397
 ACT  A 518 (-4.3A)
ACT  A 518 (-3.3A)
ACT  A 518 (-3.5A)
ACT  A 518 (-4.0A)
ACT  A 518 ( 4.2A)
 0.01A 1b2hA-1b2hA:
67.0
1b2hB-1b2hA:
undetectable		 1b2hA-1b2hA:
100.00
1b2hB-1b2hA:
4.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 LYS A 137
THR A 147
THR A  73
VAL A  71
 None
 0.78A 1ictD-1b2hA:
undetectable		 1ictD-1b2hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 SER A 477
ASP A 476
GLU A 350
GLU A 343
 None
 1.05A 1knyA-1b2hA:
0.4
1knyB-1b2hA:
0.4		 1knyA-1b2hA:
18.04
1knyB-1b2hA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A  90
HIS A  91
VAL A  94
 None
 0.41A 1lqtB-1b2hA:
undetectable		 1lqtB-1b2hA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A  90
HIS A  91
VAL A  94
 None
 0.40A 1lquB-1b2hA:
undetectable		 1lquB-1b2hA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_0
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 324
ASN A 421
LEU A 327
TYR A 321
TYR A 484
 None
 1.38A 1pj7A-1b2hA:
0.0		 1pj7A-1b2hA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A 139
ILE A 118
THR A 147
VAL A 164
PHE A 144
 None
 1.45A 1tw4A-1b2hA:
undetectable		 1tw4A-1b2hA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1131_0
(FATTY ACID-BINDING
PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 10 LEU A 139
ILE A 118
THR A 147
VAL A 164
PHE A 144
 None
 1.40A 1tw4B-1b2hA:
0.0		 1tw4B-1b2hA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 LEU A 465
ALA A 451
LEU A 449
SER A 443
 None
 0.80A 1tz8C-1b2hA:
undetectable
1tz8D-1b2hA:
undetectable		 1tz8C-1b2hA:
13.15
1tz8D-1b2hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 ALA A 445
PHE A 446
ALA A 469
LEU A 427
 None
 0.72A 2bxmA-1b2hA:
0.8		 2bxmA-1b2hA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 VAL A 233
SER A 228
ASP A 369
PRO A 249
 None
None
U1  A 522 (-3.2A)
None
 1.30A 2hdnJ-1b2hA:
undetectable
2hdnK-1b2hA:
0.0
2hdnL-1b2hA:
undetectable		 2hdnJ-1b2hA:
22.14
2hdnK-1b2hA:
7.26
2hdnL-1b2hA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 10 ALA A 296
LEU A 359
LEU A 293
LEU A 348
ARG A 288
 None
 1.06A 2riwA-1b2hA:
0.0
2riwB-1b2hA:
0.0		 2riwA-1b2hA:
20.84
2riwB-1b2hA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 VAL A 411
SER A 368
VAL A 482
TYR A 273
 None
 1.34A 2y05A-1b2hA:
undetectable
2y05B-1b2hA:
undetectable		 2y05A-1b2hA:
20.88
2y05B-1b2hA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 9 TYR A 269
PRO A 268
ILE A 507
TYR A 498
GLY A 500
 None
 1.46A 3csjB-1b2hA:
undetectable		 3csjB-1b2hA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 449
ALA A 467
LEU A 465
VAL A 328
 None
 0.99A 3d2tA-1b2hA:
undetectable		 3d2tA-1b2hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TRP A 397
PHE A 400
GLU A 396
SER A  21
 ACT  A 518 ( 4.2A)
None
None
None
 1.43A 3dqtA-1b2hA:
0.0
3dqtB-1b2hA:
undetectable		 3dqtA-1b2hA:
21.97
3dqtB-1b2hA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 GLY A 496
ARG A 265
ILE A 515
VAL A 495
 None
 1.16A 3kvvB-1b2hA:
2.8		 3kvvB-1b2hA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 GLY A 496
ARG A 265
ILE A 515
VAL A 495
 None
 1.14A 3kvvC-1b2hA:
2.8		 3kvvC-1b2hA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 GLY A 496
ARG A 265
ILE A 515
VAL A 495
 None
 1.16A 3kvvE-1b2hA:
2.3		 3kvvE-1b2hA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 SER A  21
TRP A 397
PHE A 400
GLU A 396
 None
ACT  A 518 ( 4.2A)
None
None
 1.42A 3n5tA-1b2hA:
0.0
3n5tB-1b2hA:
undetectable		 3n5tA-1b2hA:
22.18
3n5tB-1b2hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TYR A 275
LEU A 374
ALA A 377
TYR A 483
 None
 1.01A 3rodD-1b2hA:
0.0		 3rodD-1b2hA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 TYR A 420
THR A 429
TYR A 112
TYR A 115
 None
 1.15A 3wipB-1b2hA:
undetectable
3wipC-1b2hA:
undetectable		 3wipB-1b2hA:
16.28
3wipC-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 TYR A 420
TYR A 112
TYR A 115
TRP A 416
 None
 1.32A 3wipB-1b2hA:
undetectable
3wipC-1b2hA:
undetectable		 3wipB-1b2hA:
16.28
3wipC-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 TYR A 420
THR A 429
TYR A 112
TYR A 115
 None
 1.14A 3wipC-1b2hA:
undetectable
3wipD-1b2hA:
undetectable		 3wipC-1b2hA:
16.28
3wipD-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 TYR A 420
THR A 429
TYR A 112
TYR A 115
 None
 1.16A 3wipD-1b2hA:
0.0
3wipE-1b2hA:
0.0		 3wipD-1b2hA:
16.28
3wipE-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 TRP A 416
TYR A 420
TYR A 112
TYR A 115
 None
 1.34A 3wipA-1b2hA:
undetectable
3wipE-1b2hA:
undetectable		 3wipA-1b2hA:
16.28
3wipE-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TYR A 420
THR A 429
TYR A 112
TYR A 115
 None
 1.13A 3wipF-1b2hA:
0.0
3wipG-1b2hA:
undetectable		 3wipF-1b2hA:
16.28
3wipG-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 TYR A 420
THR A 429
TYR A 112
TYR A 115
 None
 1.11A 3wipF-1b2hA:
0.0
3wipJ-1b2hA:
0.0		 3wipF-1b2hA:
16.28
3wipJ-1b2hA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A 247
ARG A 413
TYR A 483
TYR A 485
 ACT  A 518 (-3.3A)
ACT  A 518 ( 4.3A)
None
None
 1.30A 4f8yA-1b2hA:
undetectable
4f8yB-1b2hA:
undetectable		 4f8yA-1b2hA:
16.96
4f8yB-1b2hA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 ARG A 413
TYR A 483
TYR A 485
ASN A 247
 ACT  A 518 ( 4.3A)
None
None
ACT  A 518 (-3.3A)
 1.13A 4f8yC-1b2hA:
1.3
4f8yD-1b2hA:
1.4		 4f8yC-1b2hA:
16.96
4f8yD-1b2hA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A 443
LEU A 465
ALA A 451
LEU A 449
 None
 0.86A 4ikjA-1b2hA:
undetectable
4ikjB-1b2hA:
undetectable		 4ikjA-1b2hA:
13.15
4ikjB-1b2hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 LEU A 465
ALA A 451
LEU A 449
SER A 443
 None
 0.89A 4ikkA-1b2hA:
undetectable
4ikkB-1b2hA:
undetectable		 4ikkA-1b2hA:
13.15
4ikkB-1b2hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TRP A 397
PHE A 400
GLU A 396
SER A  21
 ACT  A 518 ( 4.2A)
None
None
None
 1.40A 4k5jA-1b2hA:
0.0
4k5jB-1b2hA:
0.0		 4k5jA-1b2hA:
22.18
4k5jB-1b2hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		3 / 3 ASP A 122
ASP A 433
ASN A 436
 None
 0.78A 4q5mA-1b2hA:
undetectable		 4q5mA-1b2hA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 ASN A 487
LEU A 270
VAL A  34
GLY A  54
 None
 0.91A 4r3aA-1b2hA:
1.0		 4r3aA-1b2hA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		3 / 3 GLU A  32
TYR A 274
GLU A 276
 None
 0.83A 4ryaA-1b2hA:
3.4		 4ryaA-1b2hA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		3 / 3 LEU A 293
VAL A 287
ASP A 286
 None
 0.68A 4y8wC-1b2hA:
0.0		 4y8wC-1b2hA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TRP A 397
PHE A 400
GLU A 396
SER A  21
 ACT  A 518 ( 4.2A)
None
None
None
 1.42A 5adlA-1b2hA:
0.0
5adlB-1b2hA:
0.0		 5adlA-1b2hA:
22.18
5adlB-1b2hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 10 ILE A 125
GLY A 135
LEU A 134
ALA A 101
ASP A 102
 None
 1.25A 5ajqB-1b2hA:
undetectable		 5ajqB-1b2hA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 449
ALA A 467
LEU A 465
VAL A 328
 None
 1.02A 5cr1A-1b2hA:
0.0		 5cr1A-1b2hA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 TYR A 112
ASP A 419
TYR A 115
PHE A 426
 None
 1.45A 5e2iA-1b2hA:
undetectable		 5e2iA-1b2hA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TRP A 397
PHE A 400
GLU A 396
SER A  21
 ACT  A 518 ( 4.2A)
None
None
None
 1.44A 5fj3A-1b2hA:
undetectable
5fj3B-1b2hA:
undetectable		 5fj3A-1b2hA:
22.18
5fj3B-1b2hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 VAL A 152
TYR A 420
GLU A 422
LEU A 431
 None
 1.05A 5umwB-1b2hA:
1.4
5umwE-1b2hA:
1.8		 5umwB-1b2hA:
8.90
5umwE-1b2hA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 431
VAL A 152
TYR A 420
GLU A 422
 None
 1.11A 5umwA-1b2hA:
1.8
5umwF-1b2hA:
1.5		 5umwA-1b2hA:
8.90
5umwF-1b2hA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 SER A  21
TRP A 397
PHE A 400
GLU A 396
 None
ACT  A 518 ( 4.2A)
None
None
 1.46A 5uo8A-1b2hA:
0.0
5uo8B-1b2hA:
0.0		 5uo8A-1b2hA:
21.88
5uo8B-1b2hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 4 VAL A 136
LEU A 100
ASN A 120
ASP A 133
 None
 1.13A 5vcyA-1b2hA:
undetectable		 5vcyA-1b2hA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TRP A 397
PHE A 400
GLU A 396
SER A  21
 ACT  A 518 ( 4.2A)
None
None
None
 1.43A 5vv7A-1b2hA:
0.0
5vv7B-1b2hA:
0.0		 5vv7A-1b2hA:
22.18
5vv7B-1b2hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 8 ILE A 450
ASN A 437
PRO A 319
THR A 318
 None
 0.94A 5x23A-1b2hA:
0.0		 5x23A-1b2hA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 6 HIS A 161
ASN A 428
LEU A 100
GLN A 114
 None
 1.41A 5xdhA-1b2hA:
0.1
5xdhC-1b2hA:
undetectable		 5xdhA-1b2hA:
8.55
5xdhC-1b2hA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 SER A  21
TRP A 397
PHE A 400
GLU A 396
 None
ACT  A 518 ( 4.2A)
None
None
 1.44A 6av6A-1b2hA:
0.0
6av6B-1b2hA:
0.0		 6av6A-1b2hA:
10.55
6av6B-1b2hA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 TRP A 397
PHE A 400
GLU A 396
SER A  21
 ACT  A 518 ( 4.2A)
None
None
None
 1.41A 6av6C-1b2hA:
0.0
6av6D-1b2hA:
0.0		 6av6C-1b2hA:
10.55
6av6D-1b2hA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		4 / 7 SER A  21
TRP A 397
PHE A 400
GLU A 396
 None
ACT  A 518 ( 4.2A)
None
None
 1.45A 6av7A-1b2hA:
0.0
6av7B-1b2hA:
0.0		 6av7A-1b2hA:
10.55
6av7B-1b2hA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 10 GLY A 497
ASP A 242
VAL A 203
GLU A 205
TYR A 191
 None
 1.46A 6cgdA-1b2hA:
2.5		 6cgdA-1b2hA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 160
ASN A 421
ASN A 506
PRO A 503
GLY A  54
 None
 1.34A 6gnfA-1b2hA:
undetectable		 6gnfA-1b2hA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 160
ASP A 459
ASN A 421
ASN A 506
PRO A 503
 None
U1  A 521 ( 4.3A)
None
None
None
 1.29A 6gnfA-1b2hA:
undetectable		 6gnfA-1b2hA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 160
ASP A 459
ASN A 421
ASN A 506
PRO A 503
 None
U1  A 521 ( 4.3A)
None
None
None
 1.30A 6gnfC-1b2hA:
undetectable		 6gnfC-1b2hA:
23.37