SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1b2w PROTEIN (ANTIBODY
(HEAVY CHAIN))
(Homo
sapiens;
Mus
musculus) 		4 / 8 GLN H   6
VAL H 113
GLY H   8
GLY H   9
 None
 0.66A 1ekjE-1b2wH:
0.0
1ekjF-1b2wH:
undetectable		 1ekjE-1b2wH:
20.63
1ekjF-1b2wH:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1b2w PROTEIN (ANTIBODY
(HEAVY CHAIN))
(Homo
sapiens;
Mus
musculus) 		4 / 5 SER H  85
ARG H  87
PRO H  88
VAL H 115
 None
 1.29A 3sufC-1b2wH:
0.0		 3sufC-1b2wH:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1b2w PROTEIN (ANTIBODY
(HEAVY CHAIN))
(Homo
sapiens;
Mus
musculus) 		5 / 8 SER H 134
SER H 219
LEU H 128
ALA H 141
SER H 131
 None
 1.19A 4ikjA-1b2wH:
1.9
4ikjB-1b2wH:
2.3		 4ikjA-1b2wH:
19.91
4ikjB-1b2wH:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1b2w PROTEIN (ANTIBODY
(HEAVY CHAIN))
(Homo
sapiens;
Mus
musculus) 		5 / 8 LEU H 128
ALA H 141
SER H 131
SER H 134
SER H 219
 None
 1.23A 4ikkA-1b2wH:
1.9
4ikkB-1b2wH:
2.0		 4ikkA-1b2wH:
19.91
4ikkB-1b2wH:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1b2w PROTEIN (ANTIBODY
(HEAVY CHAIN))
(Homo
sapiens;
Mus
musculus) 		5 / 7 PHE H 126
GLY H 122
THR H 209
VAL H 202
VAL H 211
 None
 1.36A 5ik1A-1b2wH:
0.0		 5ik1A-1b2wH:
17.20