SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 10 ALA A 127
ALA A 131
MET A 132
LEU A  88
PHE A  58
 None
 1.34A 1rlbE-1b33A:
undetectable		 1rlbE-1b33A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		4 / 8 ALA A 126
GLY A  54
SER A 130
ALA A 131
 None
 0.89A 2vh3B-1b33A:
undetectable		 2vh3B-1b33A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		3 / 3 TYR A  87
TYR A 154
GLY A 107
 BLA  A 201 (-4.2A)
None
BLA  A 201 ( 4.0A)
 0.69A 3eteB-1b33A:
undetectable
3eteD-1b33A:
undetectable
3eteF-1b33A:
undetectable		 3eteB-1b33A:
18.24
3eteD-1b33A:
18.24
3eteF-1b33A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		4 / 7 TYR A 115
VAL A 111
VAL A 155
GLY A 107
 None
None
None
BLA  A 201 ( 4.0A)
 1.15A 3kmoB-1b33A:
1.0		 3kmoB-1b33A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 12 LEU A 159
LEU A  84
GLY A 128
ALA A 127
SER A 130
 None
BLA  A 201 ( 4.7A)
None
None
None
 0.98A 3n8zB-1b33A:
undetectable		 3n8zB-1b33A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 12 VAL A 111
ILE A 108
ILE A 122
VAL A  64
LEU A  57
 None
None
None
BLA  A 201 (-4.0A)
None
 0.90A 4y8wC-1b33A:
0.6		 4y8wC-1b33A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 12 ARG A  61
ALA A 127
THR A 120
THR A  77
LEU A  81
 None
None
BLA  A 201 ( 3.8A)
None
None
 1.40A 4z7fC-1b33A:
1.3		 4z7fC-1b33A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		4 / 7 LEU A  84
GLY A 128
ALA A 127
SER A 130
 BLA  A 201 ( 4.7A)
None
None
None
 0.82A 5f1aB-1b33A:
undetectable		 5f1aB-1b33A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 10 TYR A  87
ASP A  83
ALA A 160
ILE A 122
GLY A 107
 BLA  A 201 (-4.2A)
BLA  A 201 (-2.8A)
None
None
BLA  A 201 ( 4.0A)
 1.12A 5i6xA-1b33A:
0.8		 5i6xA-1b33A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 9 TYR A  87
ASP A  83
ALA A 160
ILE A 122
GLY A 107
 BLA  A 201 (-4.2A)
BLA  A 201 (-2.8A)
None
None
BLA  A 201 ( 4.0A)
 1.08A 6awoA-1b33A:
undetectable		 6awoA-1b33A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1b33 ALLOPHYCOCYANIN,
ALPHA CHAIN
(Mastigocladus
laminosus) 		5 / 9 TYR A  87
ASP A  83
ALA A 160
ILE A 122
GLY A 107
 BLA  A 201 (-4.2A)
BLA  A 201 (-2.8A)
None
None
BLA  A 201 ( 4.0A)
 1.08A 6awqA-1b33A:
undetectable		 6awqA-1b33A:
16.67