SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		4 / 4 LYS C 198
LEU C 205
LEU C 196
SER C 193
 None
 0.97A 1tt6A-1b35C:
0.6		 1tt6A-1b35C:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		4 / 5 LYS C 198
LEU C 205
LEU C 196
SER C 193
 None
 1.08A 1tt6B-1b35C:
0.0		 1tt6B-1b35C:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus;
Cricket
paralysis
virus) 		4 / 7 TYR A 247
THR C  42
SER A 244
VAL C  53
 None
 1.22A 1tv8B-1b35A:
undetectable		 1tv8B-1b35A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		4 / 6 LYS C 198
LEU C 205
LEU C 196
SER C 193
 None
 0.95A 1tz8C-1b35C:
undetectable
1tz8D-1b35C:
undetectable		 1tz8C-1b35C:
14.74
1tz8D-1b35C:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus;
Cricket
paralysis
virus;
Cricket
paralysis
virus) 		4 / 8 GLN A   7
MET B 185
PRO C  63
GLY B 169
 None
 0.91A 2y6rB-1b35A:
undetectable		 2y6rB-1b35A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
(Cricket
paralysis
virus) 		5 / 10 TYR B 196
PHE B 102
ILE B 187
ALA B 124
VAL B 128
 None
 1.21A 3ay0A-1b35B:
undetectable		 3ay0A-1b35B:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
(Cricket
paralysis
virus) 		4 / 8 ALA A 150
THR A  76
ILE A 196
THR A  74
 None
 0.73A 3bpxA-1b35A:
0.0
3bpxB-1b35A:
undetectable		 3bpxA-1b35A:
19.62
3bpxB-1b35A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
(Cricket
paralysis
virus) 		5 / 12 HIS B 193
PHE B 248
GLY B 201
GLY B 203
LEU B 198
 None
 1.23A 3fzgA-1b35B:
undetectable		 3fzgA-1b35B:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus;
Cricket
paralysis
virus) 		3 / 3 ASP A  23
PHE C 141
SER C 120
 None
 0.90A 3i5uB-1b35A:
undetectable		 3i5uB-1b35A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus;
Cricket
paralysis
virus) 		4 / 8 ILE A  45
LEU C  56
PHE C 114
GLY C 248
 None
 1.05A 3selX-1b35A:
undetectable		 3selX-1b35A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
(Cricket
paralysis
virus;
Cricket
paralysis
virus) 		4 / 6 ILE A 190
TYR B 189
TYR B 149
PHE A 100
 None
 1.11A 4g10A-1b35A:
undetectable		 4g10A-1b35A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
(Cricket
paralysis
virus) 		3 / 3 ALA A  13
GLN A   6
GLY A   3
 None
 0.44A 4odoC-1b35A:
0.0		 4odoC-1b35A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		3 / 3 ALA A 111
GLN C  17
GLY C  18
 None
 0.55A 4odoC-1b35A:
0.0		 4odoC-1b35A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		4 / 6 LYS C 198
LEU C 205
LEU C 196
SER C 193
 None
 0.92A 4pwjA-1b35C:
undetectable		 4pwjA-1b35C:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		4 / 6 ASP A 197
TYR C 257
PRO A 253
TYR A  96
 None
 1.14A 5bmvB-1b35A:
undetectable		 5bmvB-1b35A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)
(Cricket
paralysis
virus) 		4 / 6 LYS C 198
LEU C 205
LEU C 196
SER C 193
 None
 1.02A 5bojA-1b35C:
undetectable		 5bojA-1b35C:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
(Cricket
paralysis
virus) 		5 / 12 LEU B 126
THR B 125
ALA B 124
LEU B 122
LEU B  76
 None
 0.96A 5nfjA-1b35B:
undetectable		 5nfjA-1b35B:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
(Cricket
paralysis
virus) 		5 / 8 VAL B 237
ASP B 238
GLN B 240
GLY B 121
LEU B 198
 None
 1.29A 5w3jB-1b35B:
undetectable		 5w3jB-1b35B:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP2)
(Cricket
paralysis
virus) 		5 / 11 ASP B 174
THR B 173
THR B 181
GLY B 180
GLU B 176
 None
 1.30A 6mb5A-1b35B:
0.0		 6mb5A-1b35B:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
(Cricket
paralysis
virus) 		3 / 3 ILE A 196
THR A  76
PRO A 201
 None
 0.59A 6ncsA-1b35A:
undetectable		 6ncsA-1b35A:
19.37