SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 ALA A 149
VAL A 151
TRP A 154
 None
 0.86A 1av2C-1b3bA:
undetectable
1av2D-1b3bA:
undetectable		 1av2C-1b3bA:
6.50
1av2D-1b3bA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 4 GLY A 189
LEU A 227
GLY A 191
ARG A 190
 None
 1.28A 1j7kA-1b3bA:
2.1		 1j7kA-1b3bA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 LEU A 363
VAL A 366
LEU A 370
 None
 0.38A 1mz9B-1b3bA:
0.0		 1mz9B-1b3bA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 9 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.14A 1pxxB-1b3bA:
0.0		 1pxxB-1b3bA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 10 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.15A 1pxxD-1b3bA:
0.0		 1pxxD-1b3bA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 ALA A 149
VAL A 151
TRP A 154
 None
 0.84A 1w5uC-1b3bA:
undetectable
1w5uD-1b3bA:
undetectable		 1w5uC-1b3bA:
6.50
1w5uD-1b3bA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 ILE A 134
ILE A  71
LEU A 356
 None
 0.54A 2prgA-1b3bA:
0.0		 2prgA-1b3bA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 ASP A 337
ASN A 341
THR A 346
 None
 0.68A 2q63B-1b3bA:
0.0		 2q63B-1b3bA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 8 SER A 123
MET A  45
VAL A  43
TYR A 155
 None
 1.15A 2wekA-1b3bA:
undetectable		 2wekA-1b3bA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 7 TYR A 155
PHE A 126
PHE A  41
ILE A  71
 None
 1.19A 2zseA-1b3bA:
0.0		 2zseA-1b3bA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 ARG A 190
ASP A 362
ASN A 368
 None
 0.85A 2zzmA-1b3bA:
4.4		 2zzmA-1b3bA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 4 VAL A 345
ARG A  72
ILE A 152
THR A 188
 None
 0.99A 3cl9A-1b3bA:
0.0		 3cl9A-1b3bA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A 390
ILE A 401
ASP A 402
ALA A 400
ILE A 338
 None
 1.23A 3ddyA-1b3bA:
undetectable		 3ddyA-1b3bA:
19.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 TYR A 137
TYR A 159
ILE A 170
 None
 0.73A 3eteA-1b3bA:
50.1
3eteB-1b3bA:
50.2		 3eteA-1b3bA:
41.78
3eteB-1b3bA:
41.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 ALA A 149
VAL A 151
TRP A 154
 None
 0.84A 3l8lC-1b3bA:
undetectable
3l8lD-1b3bA:
undetectable		 3l8lC-1b3bA:
6.50
3l8lD-1b3bA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 5 ARG A 108
LEU A 122
ILE A 130
PHE A 126
 None
 1.18A 3ln1D-1b3bA:
0.0		 3ln1D-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 11 THR A 394
LEU A 339
ALA A 400
ILE A 401
THR A 346
 None
 1.43A 3qelA-1b3bA:
5.1
3qelB-1b3bA:
4.7		 3qelA-1b3bA:
20.67
3qelB-1b3bA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 11 TYR A 397
THR A 394
LEU A 339
ILE A 401
THR A 346
 None
 1.50A 3qelA-1b3bA:
5.1
3qelB-1b3bA:
4.7		 3qelA-1b3bA:
20.67
3qelB-1b3bA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 8 ILE A 246
LEU A 257
PHE A 217
GLY A 221
 None
 1.04A 3selX-1b3bA:
undetectable		 3selX-1b3bA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.05A 4coxA-1b3bA:
0.0		 4coxA-1b3bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.06A 4coxB-1b3bA:
1.1		 4coxB-1b3bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.07A 4coxD-1b3bA:
0.1		 4coxD-1b3bA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 7 ALA A 238
ILE A 246
GLY A 245
ILE A 276
 None
 0.66A 4eatA-1b3bA:
3.2		 4eatA-1b3bA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 9 GLY A 183
GLY A 191
LEU A 370
GLU A 186
GLY A 344
 None
 1.34A 4kqiA-1b3bA:
undetectable		 4kqiA-1b3bA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 5 VAL A 107
LEU A 122
VAL A  43
PHE A  41
 None
 1.05A 4lb0B-1b3bA:
0.0		 4lb0B-1b3bA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 ALA A 196
ALA A 224
ALA A 213
ILE A 288
VAL A 236
 None
 0.94A 4nkxB-1b3bA:
0.0		 4nkxB-1b3bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 ALA A 196
ALA A 224
ALA A 213
ILE A 288
VAL A 236
 None
 0.96A 4nkxD-1b3bA:
undetectable		 4nkxD-1b3bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 5 PHE A 127
PHE A 126
LEU A 119
PRO A 111
 None
 1.29A 4o8zA-1b3bA:
3.7		 4o8zA-1b3bA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.06A 4otyA-1b3bA:
1.0		 4otyA-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.06A 4otyB-1b3bA:
0.0		 4otyB-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 TYR A 159
GLY A 135
PRO A 136
 None
 0.46A 4qwpA-1b3bA:
0.0		 4qwpA-1b3bA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A  98
VAL A 345
GLY A 343
ALA A 342
LEU A 339
 None
 1.17A 4rrwA-1b3bA:
0.0		 4rrwA-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A  98
VAL A 345
GLY A 343
ALA A 342
LEU A 339
 None
 1.19A 4rrwB-1b3bA:
1.0		 4rrwB-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.09A 4rrxA-1b3bA:
undetectable		 4rrxA-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.08A 4rrxB-1b3bA:
0.0		 4rrxB-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A  98
VAL A 345
GLY A 343
ALA A 342
LEU A 339
 None
 1.17A 4rrzA-1b3bA:
0.0		 4rrzA-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A  98
VAL A 345
GLY A 343
ALA A 342
LEU A 339
 None
 1.19A 4rrzB-1b3bA:
1.0		 4rrzB-1b3bA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 10 PHE A 217
GLY A 251
LEU A 284
ALA A 213
ALA A 225
 None
 1.11A 4wnuD-1b3bA:
0.0		 4wnuD-1b3bA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 6 ILE A 332
ARG A 329
ILE A 326
GLU A 304
 None
 1.39A 4zzcB-1b3bA:
0.0
4zzcC-1b3bA:
0.0		 4zzcB-1b3bA:
23.62
4zzcC-1b3bA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 THR A 394
LEU A 339
ALA A 400
ILE A 401
THR A 346
 None
 1.50A 5ewjC-1b3bA:
4.4
5ewjD-1b3bA:
5.0		 5ewjC-1b3bA:
20.63
5ewjD-1b3bA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A 178
ILE A 130
SER A 160
TYR A 155
ILE A 152
 None
 0.99A 5h8tA-1b3bA:
undetectable		 5h8tA-1b3bA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.04A 5ikqA-1b3bA:
0.0		 5ikqA-1b3bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.02A 5ikqB-1b3bA:
0.0		 5ikqB-1b3bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A  98
VAL A 345
GLY A 343
ALA A 342
LEU A 339
 None
 1.14A 5ikrA-1b3bA:
0.0		 5ikrA-1b3bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.03A 5iktA-1b3bA:
0.0		 5iktA-1b3bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 VAL A  95
LEU A 370
VAL A 345
GLY A 343
ALA A 342
 None
 1.01A 5iktB-1b3bA:
0.0		 5iktB-1b3bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		4 / 8 ALA A  86
THR A  90
THR A  93
ALA A 407
 None
 1.02A 5x2tI-1b3bA:
undetectable
5x2tJ-1b3bA:
undetectable
5x2tK-1b3bA:
undetectable
5x2tL-1b3bA:
undetectable		 5x2tI-1b3bA:
18.09
5x2tJ-1b3bA:
17.75
5x2tK-1b3bA:
18.09
5x2tL-1b3bA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		5 / 12 LEU A 282
GLY A 216
VAL A 290
LEU A 289
ILE A 288
 None
 0.99A 6ecxA-1b3bA:
undetectable		 6ecxA-1b3bA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)
(Thermotoga
maritima) 		3 / 3 LEU A  85
GLY A  69
PHE A 126
 None
 0.65A 6exiC-1b3bA:
10.5		 6exiC-1b3bA:
11.17