SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		3 / 3 SER A 174
GLU A  62
ASP A 163
 None
 0.84A 2avdB-1b3jA:
undetectable		 2avdB-1b3jA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_A_SPMA501_1
(SPERMINE SYNTHASE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		5 / 11 VAL A 142
ASN A 141
TYR A 112
ASP A  82
GLN A  83
 None
 1.35A 3c6mA-1b3jA:
undetectable		 3c6mA-1b3jA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_C_SPMC501_1
(SPERMINE SYNTHASE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		5 / 10 VAL A 142
ASN A 141
TYR A 112
ASP A  82
GLN A  83
 None
 1.33A 3c6mC-1b3jA:
undetectable		 3c6mC-1b3jA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		4 / 4 SER A 215
HIS A 270
THR A 269
VAL A 186
 None
 1.48A 3fhxA-1b3jA:
undetectable		 3fhxA-1b3jA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		4 / 8 SER A  13
ASP A  82
LEU A 138
ASP A 113
 None
 1.08A 3n2oC-1b3jA:
undetectable
3n2oD-1b3jA:
undetectable		 3n2oC-1b3jA:
17.57
3n2oD-1b3jA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		4 / 8 SER A  13
ASP A  82
LEU A 138
ASP A 113
 None
 1.24A 3n2oC-1b3jA:
undetectable
3n2oD-1b3jA:
undetectable		 3n2oC-1b3jA:
17.57
3n2oD-1b3jA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1b3j MHC CLASS I HOMOLOG
MIC-A
(Homo
sapiens) 		4 / 5 LEU A 214
GLN A 242
THR A 243
HIS A 270
 None
 1.47A 3n58C-1b3jA:
undetectable		 3n58C-1b3jA:
17.30