SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b3n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 10 LEU A 146
TYR A 150
VAL A  79
GLY A  81
ALA A  80
 None
 1.22A 1pxxD-1b3nA:
0.0		 1pxxD-1b3nA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ILE A 177
LEU A 240
HIS A 172
ALA A 182
GLY A 101
 None
 1.33A 2a58A-1b3nA:
undetectable
2a58B-1b3nA:
undetectable		 2a58A-1b3nA:
17.59
2a58B-1b3nA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ASP A 233
GLY A 232
ILE A 108
GLY A 198
VAL A 199
 None
None
CER  A 413 (-3.3A)
CER  A 413 (-3.4A)
None
 0.84A 2avsA-1b3nA:
undetectable		 2avsA-1b3nA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ASP A 233
GLY A 232
ILE A 108
GLY A 198
ALA A  72
 None
None
CER  A 413 (-3.3A)
CER  A 413 (-3.4A)
None
 1.10A 2b7zA-1b3nA:
undetectable		 2b7zA-1b3nA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		3 / 3 VAL A   6
GLU A 242
GLU A 241
 None
 0.80A 2nv4A-1b3nA:
0.0		 2nv4A-1b3nA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		3 / 3 GLN A  31
THR A 334
TRP A  24
 None
 0.86A 2rctA-1b3nA:
0.0		 2rctA-1b3nA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		6 / 12 LEU A 146
GLY A  11
ALA A  84
ASP A  87
ILE A 170
ALA A 102
 None
 1.45A 2rkfB-1b3nA:
undetectable		 2rkfB-1b3nA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		4 / 7 SER A 263
ALA A 279
ALA A 280
ALA A 282
 None
 0.85A 3a2qA-1b3nA:
1.0		 3a2qA-1b3nA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		4 / 6 ILE A  62
MET A 149
THR A 147
LEU A 146
 None
 1.02A 3ag1N-1b3nA:
0.5
3ag1W-1b3nA:
0.0		 3ag1N-1b3nA:
21.57
3ag1W-1b3nA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		4 / 7 LEU A 341
ALA A 235
SER A 106
VAL A  79
 None
 1.00A 3d2tA-1b3nA:
0.0		 3d2tA-1b3nA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 GLY A 105
GLY A 166
ALA A 160
THR A 161
ALA A 187
 None
 1.03A 3g88A-1b3nA:
0.0		 3g88A-1b3nA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 GLY A 105
GLY A 166
ALA A 160
THR A 161
ALA A 187
 None
 1.03A 3g88B-1b3nA:
0.2		 3g88B-1b3nA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 GLY A 105
GLY A 166
ALA A 160
THR A 161
ALA A 187
 None
 1.03A 3g89A-1b3nA:
0.0		 3g89A-1b3nA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 GLY A 105
GLY A 166
ALA A 160
THR A 161
ALA A 187
 None
 1.02A 3g89B-1b3nA:
0.0		 3g89B-1b3nA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 GLY A 105
GLY A 166
ALA A 160
THR A 161
ALA A 187
 None
 1.01A 3g8bA-1b3nA:
0.5		 3g8bA-1b3nA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 GLY A 105
GLY A 166
ALA A 160
THR A 161
ALA A 187
 None
 1.02A 3g8bB-1b3nA:
0.6		 3g8bB-1b3nA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 ASP A  71
SER A 106
PHE A  56
GLU A 191
ASP A 233
 None
None
None
CER  A 413 (-3.7A)
None
 1.42A 3ko0A-1b3nA:
undetectable
3ko0B-1b3nA:
undetectable
3ko0C-1b3nA:
undetectable
3ko0D-1b3nA:
undetectable		 3ko0A-1b3nA:
12.50
3ko0B-1b3nA:
12.50
3ko0C-1b3nA:
12.50
3ko0D-1b3nA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 GLU A 191
ASP A 233
SER A 106
PHE A  56
ASP A  71
 CER  A 413 (-3.7A)
None
None
None
None
 1.43A 3ko0C-1b3nA:
undetectable
3ko0D-1b3nA:
undetectable
3ko0E-1b3nA:
undetectable
3ko0F-1b3nA:
undetectable		 3ko0C-1b3nA:
12.50
3ko0D-1b3nA:
12.50
3ko0E-1b3nA:
12.50
3ko0F-1b3nA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 GLU A 191
LEU A 342
SER A 106
PHE A  56
ASP A  71
 CER  A 413 (-3.7A)
CER  A 413 (-4.2A)
None
None
None
 1.50A 3ko0C-1b3nA:
undetectable
3ko0D-1b3nA:
undetectable
3ko0E-1b3nA:
undetectable
3ko0F-1b3nA:
undetectable		 3ko0C-1b3nA:
12.50
3ko0D-1b3nA:
12.50
3ko0E-1b3nA:
12.50
3ko0F-1b3nA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG202_1
(PROTEIN S100-A4)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 10 ASP A  71
SER A 106
PHE A  56
GLU A 191
ASP A 233
 None
None
None
CER  A 413 (-3.7A)
None
 1.48A 3ko0E-1b3nA:
undetectable
3ko0F-1b3nA:
undetectable
3ko0G-1b3nA:
undetectable
3ko0H-1b3nA:
undetectable		 3ko0E-1b3nA:
12.50
3ko0F-1b3nA:
12.50
3ko0G-1b3nA:
12.50
3ko0H-1b3nA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 11 SER A 106
PHE A  56
GLU A 191
ASP A 233
ASP A  71
 None
None
CER  A 413 (-3.7A)
None
None
 1.44A 3ko0O-1b3nA:
undetectable
3ko0P-1b3nA:
undetectable
3ko0Q-1b3nA:
0.0
3ko0R-1b3nA:
0.1		 3ko0O-1b3nA:
12.50
3ko0P-1b3nA:
12.50
3ko0Q-1b3nA:
12.50
3ko0R-1b3nA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 10 ASP A  71
SER A 106
PHE A  56
GLU A 191
ASP A 233
 None
None
None
CER  A 413 (-3.7A)
None
 1.42A 3ko0O-1b3nA:
undetectable
3ko0P-1b3nA:
undetectable
3ko0Q-1b3nA:
0.0
3ko0R-1b3nA:
0.1		 3ko0O-1b3nA:
12.50
3ko0P-1b3nA:
12.50
3ko0Q-1b3nA:
12.50
3ko0R-1b3nA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		3 / 3 SER A 333
GLY A 304
SER A 219
 None
 0.63A 3loqA-1b3nA:
undetectable		 3loqA-1b3nA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		6 / 12 GLY A 144
ALA A 143
ILE A 157
GLY A 101
ILE A 100
ILE A 104
 None
 1.41A 3ndtB-1b3nA:
undetectable		 3ndtB-1b3nA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 THR A 320
GLY A 276
ALA A 279
ALA A 282
ASN A 396
 None
 1.17A 3p5nA-1b3nA:
0.0		 3p5nA-1b3nA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		4 / 6 ALA A 187
ILE A 170
LEU A 240
ALA A  84
 None
 0.86A 3r9sC-1b3nA:
undetectable		 3r9sC-1b3nA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		3 / 3 TYR A 179
LEU A 238
ARG A 175
 None
 0.79A 3sufB-1b3nA:
0.0		 3sufB-1b3nA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		3 / 3 GLY A 399
THR A 164
ASN A 404
 CER  A 413 (-3.2A)
None
None
 0.73A 3v4tD-1b3nA:
0.0		 3v4tD-1b3nA:
25.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		11 / 12 GLY A 107
ALA A 162
CYH A 163
GLU A 191
PHE A 202
HIS A 303
THR A 305
HIS A 340
LEU A 342
GLY A 399
PHE A 400
 CER  A 413 ( 3.8A)
CER  A 413 (-3.1A)
CER  A 413 ( 1.8A)
CER  A 413 (-3.7A)
CER  A 413 (-4.5A)
CER  A 413 (-4.0A)
CER  A 413 ( 4.8A)
CER  A 413 (-4.2A)
CER  A 413 (-4.2A)
CER  A 413 (-3.2A)
CER  A 413 (-3.3A)
 0.32A 4ls7A-1b3nA:
69.6		 4ls7A-1b3nA:
52.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		7 / 12 GLY A 343
ALA A 162
GLU A 191
PHE A 202
LEU A 342
GLY A 399
PHE A 400
 None
CER  A 413 (-3.1A)
CER  A 413 (-3.7A)
CER  A 413 (-4.5A)
CER  A 413 (-4.2A)
CER  A 413 (-3.2A)
CER  A 413 (-3.3A)
 1.49A 4ls7A-1b3nA:
69.6		 4ls7A-1b3nA:
52.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		10 / 12 ILE A 108
ALA A 162
CYH A 163
PHE A 202
HIS A 303
THR A 305
HIS A 340
LEU A 342
GLY A 399
PHE A 400
 CER  A 413 (-3.3A)
CER  A 413 (-3.1A)
CER  A 413 ( 1.8A)
CER  A 413 (-4.5A)
CER  A 413 (-4.0A)
CER  A 413 ( 4.8A)
CER  A 413 (-4.2A)
CER  A 413 (-4.2A)
CER  A 413 (-3.2A)
CER  A 413 (-3.3A)
 0.39A 4ls7A-1b3nA:
69.6
4ls7B-1b3nA:
69.4		 4ls7A-1b3nA:
52.72
4ls7B-1b3nA:
52.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 LEU A 231
ALA A 207
PHE A 229
ILE A 108
GLY A 201
 None
None
None
CER  A 413 (-3.3A)
None
 0.94A 4nkxB-1b3nA:
undetectable		 4nkxB-1b3nA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 LEU A 240
VAL A 167
GLY A 166
SER A 350
LEU A 407
 None
 1.34A 4ot2A-1b3nA:
undetectable		 4ot2A-1b3nA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 9 ALA A 190
ALA A 235
ILE A 108
GLY A 110
ASP A 233
 None
None
CER  A 413 (-3.3A)
None
None
 1.12A 4qvqK-1b3nA:
undetectable
4qvqL-1b3nA:
undetectable		 4qvqK-1b3nA:
19.62
4qvqL-1b3nA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 9 ALA A 190
ALA A 235
ILE A 108
GLY A 110
ASP A 233
 None
None
CER  A 413 (-3.3A)
None
None
 1.12A 4qvqY-1b3nA:
undetectable
4qvqZ-1b3nA:
undetectable		 4qvqY-1b3nA:
19.62
4qvqZ-1b3nA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ALA A 235
ALA A 143
ILE A 104
GLY A  11
GLN A  83
 None
 1.09A 4r38A-1b3nA:
undetectable		 4r38A-1b3nA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ALA A 235
ALA A 143
ILE A 104
GLY A  11
GLN A  83
 None
 1.01A 4r38B-1b3nA:
undetectable		 4r38B-1b3nA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ALA A 235
ALA A 143
ILE A 104
GLY A  11
GLN A  83
 None
 1.08A 4r38C-1b3nA:
undetectable		 4r38C-1b3nA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ALA A 235
ALA A 143
ILE A 104
GLY A  11
GLN A  83
 None
 1.08A 4r38D-1b3nA:
undetectable		 4r38D-1b3nA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		4 / 8 ALA A 173
ALA A 174
ILE A 177
ALA A 255
 None
 0.67A 4v1fA-1b3nA:
undetectable
4v1fB-1b3nA:
0.0		 4v1fA-1b3nA:
13.95
4v1fB-1b3nA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 GLY A 343
LEU A 407
ARG A 175
ALA A 173
HIS A 172
 None
 1.23A 4wcxC-1b3nA:
undetectable		 4wcxC-1b3nA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 8 ALA A 190
VAL A 142
GLY A 236
ALA A 347
GLY A 188
 None
 1.19A 4zjzB-1b3nA:
undetectable		 4zjzB-1b3nA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 GLY A 171
ILE A 177
ALA A 187
GLY A 188
ALA A 103
 None
 0.89A 5kb6A-1b3nA:
undetectable		 5kb6A-1b3nA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 GLY A 171
ILE A 177
ALA A 187
GLY A 188
ALA A 103
 None
 0.87A 5kb6B-1b3nA:
undetectable		 5kb6B-1b3nA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 LEU A 240
ALA A 174
THR A 164
ALA A 187
ILE A 159
 None
 1.02A 5xiwB-1b3nA:
undetectable		 5xiwB-1b3nA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1b3n PROTEIN (KETOACYL
ACYL CARRIER PROTEIN
SYNTHASE 2)
(Escherichia
coli) 		5 / 12 ILE A 408
LEU A 394
GLY A 298
PHE A 322
ALA A 294
 None
 1.12A 6c2mA-1b3nA:
0.0		 6c2mA-1b3nA:
11.96