SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 1b47 CBL
(Homo
sapiens) 		4 / 6 PRO A 214
HIS A 213
TRP A 202
GLU A 220
 None
 1.37A 1ffyA-1b47A:
0.0		 1ffyA-1b47A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 1b47 CBL
(Homo
sapiens) 		5 / 12 LEU A  88
LEU A 151
THR A 152
LEU A 154
PHE A 158
 None
 0.81A 2bdmA-1b47A:
0.0		 2bdmA-1b47A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 1b47 CBL
(Homo
sapiens) 		5 / 12 LEU A  88
THR A 152
LEU A 154
SER A 155
PHE A 158
 None
 0.80A 2bdmA-1b47A:
0.0		 2bdmA-1b47A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1b47 CBL
(Homo
sapiens) 		3 / 3 LEU A 300
LEU A  87
PHE A 271
 None
 0.73A 2pgrA-1b47A:
undetectable		 2pgrA-1b47A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 1b47 CBL
(Homo
sapiens) 		5 / 11 LEU A 230
TYR A 268
ALA A 262
PHE A 248
PHE A 244
 None
 1.08A 4evrA-1b47A:
0.1		 4evrA-1b47A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b47 CBL
(Homo
sapiens) 		4 / 8 GLU A  57
LEU A  88
LEU A  95
MET A 119
 None
 0.95A 4r38B-1b47A:
1.5		 4r38B-1b47A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 1b47 CBL
(Homo
sapiens) 		4 / 6 ARG A 256
PHE A 248
ILE A 228
THR A 227
 None
 1.11A 5vceA-1b47A:
0.3		 5vceA-1b47A:
21.12