SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		5 / 11 GLY A 150
TYR A  95
ILE A  92
ARG A  91
HIS A 143
 None
 1.32A 1tmxA-1b48A:
undetectable		 1tmxA-1b48A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		5 / 12 GLY A 150
TYR A  95
ILE A  92
ARG A  91
HIS A 143
 None
 1.43A 1tmxB-1b48A:
undetectable		 1tmxB-1b48A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		4 / 6 MET A  64
VAL A  58
LEU A  57
MET A  44
 None
 1.18A 1x8vA-1b48A:
0.0		 1x8vA-1b48A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		4 / 7 ARG A  89
GLU A  88
ALA A  96
ALA A 156
 None
 1.07A 2ejfA-1b48A:
undetectable		 2ejfA-1b48A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		4 / 6 LEU A 161
GLU A 168
ALA A 163
THR A  99
 None
 1.01A 2roxB-1b48A:
undetectable		 2roxB-1b48A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1469_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		4 / 4 GLN A 182
GLU A 168
LEU A 175
SER A 176
 None
 1.47A 2xrzA-1b48A:
0.0		 2xrzA-1b48A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		4 / 8 LEU A 198
SER A 189
ALA A  24
ALA A  25
 None
 0.92A 3ax9B-1b48A:
0.0		 3ax9B-1b48A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		5 / 11 ASP A 177
SER A 176
PHE A 133
LEU A 170
ILE A 124
 None
 1.35A 3ko0K-1b48A:
0.3
3ko0L-1b48A:
0.3
3ko0M-1b48A:
0.3
3ko0N-1b48A:
undetectable		 3ko0K-1b48A:
17.94
3ko0L-1b48A:
17.94
3ko0M-1b48A:
17.94
3ko0N-1b48A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		5 / 10 PHE A 133
ASP A 177
SER A 176
LEU A 170
ILE A 124
 None
 1.30A 3ko0O-1b48A:
0.2
3ko0P-1b48A:
0.3
3ko0Q-1b48A:
0.0
3ko0R-1b48A:
0.3		 3ko0O-1b48A:
17.94
3ko0P-1b48A:
17.94
3ko0Q-1b48A:
17.94
3ko0R-1b48A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		5 / 11 ASP A 177
SER A 176
PHE A 133
LEU A 170
ILE A 124
 None
 1.28A 3ko0Q-1b48A:
0.0
3ko0R-1b48A:
0.0
3ko0S-1b48A:
undetectable
3ko0T-1b48A:
undetectable		 3ko0Q-1b48A:
17.94
3ko0R-1b48A:
17.94
3ko0S-1b48A:
17.94
3ko0T-1b48A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		4 / 7 LEU A 198
LEU A 161
SER A  18
THR A  99
 None
 0.97A 3lm8A-1b48A:
undetectable
3lm8C-1b48A:
undetectable		 3lm8A-1b48A:
23.75
3lm8C-1b48A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		3 / 3 LEU A   7
ILE A  19
TYR A  79
 None
 0.58A 5uunB-1b48A:
12.5		 5uunB-1b48A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 1b48 PROTEIN (GLUTATHIONE
S-TRANSFERASE)
(Mus
musculus) 		5 / 12 PHE A 147
ILE A 188
ILE A 194
ALA A  24
ALA A  76
 None
 0.96A 5vceA-1b48A:
undetectable		 5vceA-1b48A:
17.86