SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b55'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1b55 TYROSINE-PROTEIN
KINASE BTK
(Homo
sapiens) 		4 / 6 ASP A  57
ILE A  56
GLN A  15
GLU A 108
 None
None
4IP  A 171 (-4.6A)
None
 1.29A 2ya7C-1b55A:
0.0		 2ya7C-1b55A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1b55 TYROSINE-PROTEIN
KINASE BTK
(Homo
sapiens) 		3 / 3 SER A  21
GLU A 108
ASP A  57
 4IP  A 171 (-2.5A)
None
None
 0.81A 2zulA-1b55A:
undetectable		 2zulA-1b55A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 1b55 TYROSINE-PROTEIN
KINASE BTK
(Homo
sapiens) 		4 / 5 ILE A  79
PRO A  99
PHE A 114
PRO A 101
 None
 1.17A 3bjwC-1b55A:
0.0		 3bjwC-1b55A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1b55 TYROSINE-PROTEIN
KINASE BTK
(Homo
sapiens) 		3 / 3 SER A  21
GLU A 108
ASP A  57
 4IP  A 171 (-2.5A)
None
None
 0.80A 3dmhA-1b55A:
undetectable		 3dmhA-1b55A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 1b55 TYROSINE-PROTEIN
KINASE BTK
(Homo
sapiens) 		3 / 3 TYR A 106
TYR A  39
GLN A  15
 None
4IP  A 171 (-4.6A)
4IP  A 171 (-4.6A)
 1.17A 5jsdA-1b55A:
0.0
5jsdB-1b55A:
0.0		 5jsdA-1b55A:
11.66
5jsdB-1b55A:
11.66