SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 7 PHE A 213
TYR A 189
ASP A 215
ILE B 300
 None
 0.91A 1p7rA-1b5fA:
0.0		 1p7rA-1b5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 7 SER A  42
LYS A  44
SER A  85
SER A  58
 None
 1.25A 2j9cA-1b5fA:
0.0
2j9cB-1b5fA:
0.0
2j9cC-1b5fA:
0.0		 2j9cA-1b5fA:
18.14
2j9cB-1b5fA:
18.14
2j9cC-1b5fA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 7 SER A  85
SER A  58
SER A  42
LYS A  44
 None
 1.33A 2j9cA-1b5fA:
0.0
2j9cB-1b5fA:
0.0
2j9cC-1b5fA:
0.0		 2j9cA-1b5fA:
18.14
2j9cB-1b5fA:
18.14
2j9cC-1b5fA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1b5f PROTEIN (CARDOSIN A)
PROTEIN (CARDOSIN A)
(Cynara
cardunculus;
Cynara
cardunculus) 		4 / 8 PHE A 213
TYR A 189
ASP A 215
ILE B 300
 None
 0.98A 2qbmA-1b5fA:
0.0		 2qbmA-1b5fA:
20.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ASP A  32
GLY A  34
SER A  35
ASP A 215
GLY A 217
SER A 219
 None
 0.68A 2v0zC-1b5fA:
7.5		 2v0zC-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  75
GLY A 217
SER A  13
 None
 1.16A 2v0zC-1b5fA:
7.5		 2v0zC-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		7 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  75
PHE A 117
ASP A 215
GLY A 217
 None
 0.48A 2v0zC-1b5fA:
7.5		 2v0zC-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A 215
GLY A 217
ASP A  32
GLY A  34
SER A  36
 None
 0.75A 2v0zC-1b5fA:
7.5		 2v0zC-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
GLY A 217
SER A 219
 None
 0.70A 2v0zO-1b5fA:
28.5		 2v0zO-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A  32
GLY A  34
PHE A 117
ASP A 215
GLY A 217
 None
 0.35A 2v0zO-1b5fA:
28.5		 2v0zO-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A 215
GLY A 217
ASP A  32
GLY A  34
SER A  36
 None
 0.72A 2v0zO-1b5fA:
28.5		 2v0zO-1b5fA:
34.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_2
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 8 TYR A  14
SER A  35
TYR A  75
THR A  77
 None
 0.72A 2v0zO-1b5fA:
28.5		 2v0zO-1b5fA:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 8 TYR A 138
SER A  35
GLN A  99
ILE A 132
 None
 1.04A 2xz5B-1b5fA:
0.0
2xz5E-1b5fA:
0.0		 2xz5B-1b5fA:
22.13
2xz5E-1b5fA:
22.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
SER A 219
SER A 222
 None
 0.94A 3d91A-1b5fA:
6.7		 3d91A-1b5fA:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ASP A  32
GLY A  34
THR A  77
PHE A 117
ASP A 215
SER A 222
 None
 0.95A 3d91A-1b5fA:
6.7		 3d91A-1b5fA:
34.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
SER A 219
SER A 222
 None
 1.02A 3d91B-1b5fA:
27.9		 3d91B-1b5fA:
34.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 SER A  61
LEU A  38
ILE A  18
SER A  88
GLY A  19
 None
 1.41A 3ijxB-1b5fA:
undetectable
3ijxD-1b5fA:
undetectable		 3ijxB-1b5fA:
21.35
3ijxD-1b5fA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 ILE A  18
SER A  88
GLY A  19
SER A  61
LEU A  38
 None
 1.42A 3ik6B-1b5fA:
0.0
3ik6E-1b5fA:
0.0		 3ik6B-1b5fA:
21.35
3ik6E-1b5fA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 SER A  61
LEU A  38
ILE A  18
SER A  88
GLY A  19
 None
 1.43A 3iluB-1b5fA:
0.0
3iluE-1b5fA:
0.0		 3iluB-1b5fA:
21.35
3iluE-1b5fA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 8 TYR B 274
GLY A 223
THR A 204
ILE A 199
 None
 0.81A 3jusB-1b5fB:
0.0		 3jusB-1b5fB:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 TYR B 274
PHE B 260
GLY A 223
THR A 204
ILE A 199
 None
 0.89A 3ld6A-1b5fB:
undetectable		 3ld6A-1b5fB:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 TYR B 274
PHE B 260
GLY A 223
THR A 204
ILE A 199
 None
 0.91A 3ld6B-1b5fB:
undetectable		 3ld6B-1b5fB:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 6 TYR A  75
ILE A  80
SER A  36
SER A  35
 None
 1.29A 3pmzD-1b5fA:
0.0		 3pmzD-1b5fA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ASP A  32
GLY A  34
ASP A   9
ASP A 215
THR A 218
ILE B 300
 None
 1.22A 3prsA-1b5fA:
25.0		 3prsA-1b5fA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ASP A  32
GLY A  34
GLY A  76
ASP A 215
THR A 218
ILE B 300
 None
 0.43A 3prsA-1b5fA:
25.0		 3prsA-1b5fA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ASP A  32
GLY A  76
PHE A 112
THR A 218
ILE B 300
 None
 0.60A 3pwwA-1b5fA:
24.9		 3pwwA-1b5fA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 8 GLY A  34
SER A  35
ILE A  73
TYR A  75
ASP A 215
 None
 0.37A 3pwwA-1b5fA:
24.9		 3pwwA-1b5fA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		7 / 12 ILE A  30
ASP A  32
GLY A  34
GLY A  76
ASP A 215
THR A 218
ILE B 300
 None
 0.41A 3q70A-1b5fA:
23.3		 3q70A-1b5fA:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ILE A 120
ASP A  32
GLY A  34
ASP A 215
THR A 218
ILE B 300
 None
 1.17A 3q70A-1b5fA:
23.3		 3q70A-1b5fA:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ILE A 120
ASP A  32
ILE A  73
ASP A 215
THR A 218
ILE B 300
 None
 1.29A 3q70A-1b5fA:
23.3		 3q70A-1b5fA:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 6 SER A  35
ILE A  73
TYR A  75
ASP A 118
 None
 0.93A 3q70A-1b5fA:
23.3		 3q70A-1b5fA:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 6 GLY A  21
VAL A  95
SER A  88
THR A  90
 None
 0.93A 3tj7C-1b5fA:
0.0
3tj7D-1b5fA:
0.0		 3tj7C-1b5fA:
22.95
3tj7D-1b5fA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A   9
ASP A 215
ILE B 300
 None
 1.43A 3tneA-1b5fA:
22.9		 3tneA-1b5fA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		7 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  73
GLY A  76
ASP A 215
ILE B 300
 None
 0.43A 3tneA-1b5fA:
22.9		 3tneA-1b5fA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		6 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A   9
ASP A 215
ILE B 300
 None
 1.38A 3tneB-1b5fA:
22.8		 3tneB-1b5fA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		7 / 12 ILE A  30
ASP A  32
GLY A  34
ILE A  73
GLY A  76
ASP A 215
ILE B 300
 None
 0.44A 3tneB-1b5fA:
22.8		 3tneB-1b5fA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 7 SER A  35
TYR A  75
ILE A 120
THR A 218
 None
 0.47A 3tneB-1b5fA:
22.8		 3tneB-1b5fA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 8 ASP A  87
ILE A  20
GLY A  21
VAL A  29
 None
 0.69A 4acbB-1b5fA:
undetectable
4acbC-1b5fA:
undetectable		 4acbB-1b5fA:
20.92
4acbC-1b5fA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 GLU A 107
TRP A  39
LYS A  48
 None
 1.42A 4k7aA-1b5fA:
undetectable		 4k7aA-1b5fA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.88A 4k8cA-1b5fA:
undetectable		 4k8cA-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.88A 4kahA-1b5fA:
undetectable		 4kahA-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.89A 4kahB-1b5fA:
undetectable		 4kahB-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.87A 4kanA-1b5fA:
undetectable		 4kanA-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.89A 4kanB-1b5fA:
undetectable		 4kanB-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.92A 4kbeA-1b5fA:
undetectable		 4kbeA-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.90A 4kbeB-1b5fA:
undetectable		 4kbeB-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1b5f PROTEIN (CARDOSIN A)
PROTEIN (CARDOSIN A)
(Cynara
cardunculus;
Cynara
cardunculus) 		4 / 8 PHE A 213
TYR A 189
ASP A 215
ILE B 300
 None
 0.93A 4l4cB-1b5fA:
0.0		 4l4cB-1b5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.88A 4lbgA-1b5fA:
undetectable		 4lbgA-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.87A 4lbgB-1b5fA:
undetectable		 4lbgB-1b5fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1b5f PROTEIN (CARDOSIN A)
PROTEIN (CARDOSIN A)
(Cynara
cardunculus;
Cynara
cardunculus) 		3 / 3 ILE A  30
ASP B 303
ARG A 115
 None
 0.62A 4pstA-1b5fA:
undetectable		 4pstA-1b5fA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 1b5f PROTEIN (CARDOSIN A)
PROTEIN (CARDOSIN A)
(Cynara
cardunculus;
Cynara
cardunculus) 		4 / 4 THR B 287
GLY B 302
ASP B 303
SER A 222
 None
 0.92A 4rfqA-1b5fB:
undetectable		 4rfqA-1b5fB:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 6 PHE A 125
LEU A 123
TRP A 190
GLY A  34
 None
 0.96A 5o4yA-1b5fA:
undetectable		 5o4yA-1b5fA:
3.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 6 PHE A 125
LEU A 123
TRP A 190
GLY A  34
 None
 1.14A 5o4yF-1b5fA:
undetectable		 5o4yF-1b5fA:
3.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 7 ILE A  18
LEU A   6
PHE A 153
THR A  33
 None
 1.04A 5vc0A-1b5fA:
0.0		 5vc0A-1b5fA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_A_CP6A704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 ALA A  72
PHE A  84
THR A 128
VAL A  37
THR A  81
 None
NAG  A 401 ( 3.9A)
None
None
None
 1.48A 6aogA-1b5fA:
undetectable		 6aogA-1b5fA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_B_CP6B704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 ALA A  72
PHE A  84
THR A 128
VAL A  37
THR A  81
 None
NAG  A 401 ( 3.9A)
None
None
None
 1.49A 6aogB-1b5fA:
undetectable		 6aogB-1b5fA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 SER A  61
LEU A  38
ILE A  18
SER A  88
GLY A  19
 None
 1.35A 6dlzA-1b5fA:
undetectable
6dlzD-1b5fA:
undetectable		 6dlzA-1b5fA:
16.91
6dlzD-1b5fA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 ILE A  18
SER A  88
GLY A  19
SER A  61
LEU A  38
 None
 1.35A 6dlzB-1b5fA:
undetectable
6dlzC-1b5fA:
undetectable		 6dlzB-1b5fA:
16.91
6dlzC-1b5fA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 SER A  61
LEU A  38
ILE A  18
SER A  88
GLY A  19
 None
 1.30A 6dm0B-1b5fA:
undetectable
6dm0C-1b5fA:
undetectable		 6dm0B-1b5fA:
16.91
6dm0C-1b5fA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 SER A  61
LEU A  38
ILE A  18
SER A  88
GLY A  19
 None
 1.36A 6dm1A-1b5fA:
undetectable
6dm1D-1b5fA:
undetectable		 6dm1A-1b5fA:
16.91
6dm1D-1b5fA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 10 ILE A  18
SER A  88
GLY A  19
SER A  61
LEU A  38
 None
 1.36A 6dm1B-1b5fA:
undetectable
6dm1C-1b5fA:
undetectable		 6dm1B-1b5fA:
16.91
6dm1C-1b5fA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA717_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		4 / 5 SER A  13
ARG A 115
ASP A   9
ARG A  10
 None
 1.20A 6dwdA-1b5fA:
0.0		 6dwdA-1b5fA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 1b5f PROTEIN (CARDOSIN A)
(Cynara
cardunculus) 		5 / 12 ILE A 132
SER A  36
ASN A  67
PHE A  84
ILE A  73
 None
None
NAG  A 401 ( 1.8A)
NAG  A 401 ( 3.9A)
None
 1.37A 6dwnB-1b5fA:
undetectable		 6dwnB-1b5fA:
14.81