SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 TYR A  75
PRO A 102
PHE A  99
LEU A 100
PRO A 140
 None
 1.40A 1klmA-1b65A:
undetectable		 1klmA-1b65A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		3 / 3 ARG A  53
VAL A 158
GLY A 181
 None
 0.58A 2avvE-1b65A:
0.0		 2avvE-1b65A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 8 GLY A 196
GLU A 177
GLY A 178
ALA A 343
ALA A 342
 None
 1.21A 2ej3C-1b65A:
undetectable		 2ej3C-1b65A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 10 THR A  60
ALA A  61
ALA A 166
VAL A 158
ALA A 114
 None
 1.02A 2f16K-1b65A:
undetectable
2f16L-1b65A:
undetectable		 2f16K-1b65A:
22.54
2f16L-1b65A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 10 THR A  60
ALA A  61
ALA A 166
VAL A 158
ALA A 114
 None
 1.01A 2f16Y-1b65A:
undetectable
2f16Z-1b65A:
undetectable		 2f16Y-1b65A:
22.54
2f16Z-1b65A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 8 THR A 145
GLY A 183
THR A  60
ILE A 105
 None
 0.96A 2f9wA-1b65A:
undetectable
2f9wB-1b65A:
undetectable		 2f9wA-1b65A:
21.76
2f9wB-1b65A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 8 THR A 145
GLY A 194
THR A  60
ILE A 105
 None
 0.93A 2f9wA-1b65A:
undetectable
2f9wB-1b65A:
undetectable		 2f9wA-1b65A:
21.76
2f9wB-1b65A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 GLY A  24
THR A  23
THR A  30
ARG A  11
GLY A 212
 None
 1.00A 2fn1B-1b65A:
undetectable		 2fn1B-1b65A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 ILE A  29
GLY A  24
THR A  30
ARG A  11
GLY A 212
 None
 1.07A 2fn1B-1b65A:
undetectable		 2fn1B-1b65A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 4 LEU A 259
PRO A 260
LEU A 261
ARG A 268
 None
 1.42A 2qd2A-1b65A:
undetectable		 2qd2A-1b65A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 10 THR A  41
LEU A 150
VAL A 356
GLY A 193
THR A 184
 None
 1.22A 2wd9C-1b65A:
undetectable		 2wd9C-1b65A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 4 PRO A  25
THR A  23
GLY A 196
THR A 195
 None
 1.06A 3ib1A-1b65A:
undetectable		 3ib1A-1b65A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 6 VAL A 163
ILE A 293
ALA A  61
LEU A 167
 None
 0.82A 3kk6B-1b65A:
0.0		 3kk6B-1b65A:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 GLY A  85
THR A 108
GLU A 144
ASN A 218
SER A 250
 None
 0.35A 3ndvA-1b65A:
52.0
3ndvB-1b65A:
52.0		 3ndvA-1b65A:
41.79
3ndvB-1b65A:
41.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 GLY A  85
THR A 108
GLU A 144
ASN A 218
SER A 250
 None
 0.33A 3ndvA-1b65A:
52.0
3ndvB-1b65A:
52.0		 3ndvA-1b65A:
41.79
3ndvB-1b65A:
41.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 GLY A  85
THR A 108
GLU A 144
ASN A 218
SER A 250
 None
 0.33A 3ndvC-1b65A:
52.0
3ndvD-1b65A:
51.9		 3ndvC-1b65A:
41.79
3ndvD-1b65A:
41.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 GLY A  85
THR A 108
GLU A 144
ASN A 218
SER A 250
 None
 0.34A 3ndvC-1b65A:
52.0
3ndvD-1b65A:
51.9		 3ndvC-1b65A:
41.79
3ndvD-1b65A:
41.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 12 GLY A 196
GLY A 194
ASN A 179
ALA A 213
ALA A 198
 None
 1.06A 3p2kA-1b65A:
undetectable		 3p2kA-1b65A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		3 / 3 LYS A 267
VAL A  78
HIS A  79
 None
 1.12A 3tj7A-1b65A:
0.0		 3tj7A-1b65A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 GLY A 193
GLY A 194
GLY A 183
ALA A 343
GLN A 176
 None
 1.11A 4l8fB-1b65A:
undetectable		 4l8fB-1b65A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 12 GLY A 205
LEU A 261
LEU A 269
ARG A 272
ALA A 327
 None
 1.21A 4wcxC-1b65A:
undetectable		 4wcxC-1b65A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 5 ILE A  62
VAL A 254
ILE A 252
VAL A 103
 None
 0.75A 4xdtA-1b65A:
0.0		 4xdtA-1b65A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 5 ILE A 293
VAL A 103
ILE A 105
VAL A 254
 None
 0.69A 4xdtA-1b65A:
0.0		 4xdtA-1b65A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 11 THR A 108
GLN A 216
GLU A 144
GLY A 289
GLY A  85
 None
 1.34A 5e3iB-1b65A:
undetectable		 5e3iB-1b65A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 12 GLU A 144
ASP A 290
ASN A 218
ALA A 339
VAL A 332
 None
 1.35A 5kbwB-1b65A:
0.0		 5kbwB-1b65A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 12 GLY A 182
GLY A  58
THR A 184
VAL A 104
ALA A  61
 None
 0.94A 5kpcA-1b65A:
undetectable		 5kpcA-1b65A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		5 / 10 ARG A 222
ALA A 149
ASP A 147
GLY A 347
ILE A 187
 None
 1.01A 5kr1A-1b65A:
undetectable		 5kr1A-1b65A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 6 GLU A 362
ARG A 365
LEU A 364
ARG A 363
 None
 1.22A 5l6eA-1b65A:
undetectable
5l6eB-1b65A:
undetectable		 5l6eA-1b65A:
18.85
5l6eB-1b65A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		4 / 6 PHE A 209
THR A 257
ASP A  31
GLY A  24
 None
 1.04A 5mraA-1b65A:
undetectable
5mraB-1b65A:
undetectable		 5mraA-1b65A:
19.05
5mraB-1b65A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		3 / 3 ILE A 111
VAL A 142
PRO A 140
 None
 0.73A 5uunA-1b65A:
undetectable		 5uunA-1b65A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1b65 PROTEIN
(AMINOPEPTIDASE)
(Ochrobactrum
anthropi) 		3 / 3 GLY A 183
VAL A 356
MET A 346
 None
 0.47A 5ycpA-1b65A:
0.0		 5ycpA-1b65A:
11.53