SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1b69 PROTEIN (INTEGRASE)
(Enterococcus
faecalis) 		5 / 12 ILE A  58
ALA A  57
LEU A  60
SER A  41
LEU A  67
 None
 1.16A 4lnwA-1b69A:
undetectable		 4lnwA-1b69A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1b69 PROTEIN (INTEGRASE)
(Enterococcus
faecalis) 		5 / 12 ILE A  58
ALA A  57
LEU A  60
SER A  41
LEU A  67
 None
 1.16A 4lnxA-1b69A:
undetectable		 4lnxA-1b69A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 1b69 PROTEIN (INTEGRASE)
(Enterococcus
faecalis) 		4 / 7 VAL A  39
LEU A  60
SER A  59
GLU A  62
 None
 1.08A 4zphA-1b69A:
undetectable
4zphB-1b69A:
0.0		 4zphA-1b69A:
10.35
4zphB-1b69A:
9.86