SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))
1b72 PROTEIN (HOMEOBOX
PROTEIN HOX-B1)

(Homo
sapiens)
3 / 3 ARG A 213
GLU A 217
GLN A 214
None
0.99A 2p16A-1b72A:
undetectable
2p16A-1b72A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)
1b72 PROTEIN (HOMEOBOX
PROTEIN HOX-B1)

(Homo
sapiens)
3 / 3 TRP A 250
ARG A 254
LEU A 228
None
0.75A 5dbyA-1b72A:
undetectable
5dbyA-1b72A:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
1b72 PROTEIN (HOMEOBOX
PROTEIN HOX-B1)

(Homo
sapiens)
5 / 7 VAL A 247
LEU A 218
GLU A 244
ALA A 237
LEU A 228
None
1.20A 5jq7A-1b72A:
undetectable
5jq7A-1b72A:
14.42