SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KF6_B_ACTB704_0 (FUMARATE REDUCTASE FLAVOPROTEIN FUMARATE REDUCTASE IRON-SULFUR PROTEIN)	1b88	T CELL RECEPTOR V-ALPHA DOMAIN (Mus musculus)	3 / 3	ARG A 61 GLY A 83 ASP A 84	None	0.57A	1kf6A-1b88A: undetectable 1kf6B-1b88A: 0.0	1kf6A-1b88A: 11.77 1kf6B-1b88A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_B_ANWB99_0 (PROTEIN S100-A13)	1b88	T CELL RECEPTOR V-ALPHA DOMAIN (Mus musculus)	4 / 8	ALA A 78 THR A 63 PHE A 62 ASP A 84	None	0.97A	2kotB-1b88A: undetectable	2kotB-1b88A: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS6_B_EPAB1_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1b88	T CELL RECEPTOR V-ALPHA DOMAIN (Mus musculus)	5 / 12	PHE A 66 ILE A 50 PHE A 33 TYR A 25 ALA A 94	None	1.00A	3hs6B-1b88A: undetectable	3hs6B-1b88A: 10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_A_LNLA701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1b88	T CELL RECEPTOR V-ALPHA DOMAIN (Mus musculus)	5 / 12	PHE A 66 ILE A 50 PHE A 33 TYR A 25 ALA A 94	None	1.05A	4e1gA-1b88A: undetectable	4e1gA-1b88A: 10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_B_LNLB701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1b88	T CELL RECEPTOR V-ALPHA DOMAIN (Mus musculus)	5 / 12	PHE A 66 ILE A 50 PHE A 33 TYR A 25 ALA A 94	None	1.04A	4e1gB-1b88A: undetectable	4e1gB-1b88A: 10.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KF6_B_ACTB704_0","FUMARATE REDUCTASE FLAVOPROTEIN;FUMARATE REDUCTASE IRON-SULFUR PROTEIN","1b88","T CELL RECEPTOR V-ALPHA DOMAIN","Mus musculus",3,"ARG A  61;GLY A  83;ASP A  84","None","0.57A","1kf6A-1b88A:undetectable;1kf6B-1b88A:0.0","1kf6A-1b88A:11.77;1kf6B-1b88A:18.67"],["2KOT_B_ANWB99_0","PROTEIN S100-A13","1b88","T CELL RECEPTOR V-ALPHA DOMAIN","Mus musculus",4,"ALA A  78;THR A  63;PHE A  62;ASP A  84","None","0.97A","2kotB-1b88A:undetectable","2kotB-1b88A:25.00"],["3HS6_B_EPAB1_1","PROSTAGLANDIN G\/H SYNTHASE 2","1b88","T CELL RECEPTOR V-ALPHA DOMAIN","Mus musculus",5,"PHE A  66;ILE A  50;PHE A  33;TYR A  25;ALA A  94","None","1.00A","3hs6B-1b88A:undetectable","3hs6B-1b88A:10.49"],["4E1G_A_LNLA701_1","PROSTAGLANDIN G\/H SYNTHASE 2","1b88","T CELL RECEPTOR V-ALPHA DOMAIN","Mus musculus",5,"PHE A  66;ILE A  50;PHE A  33;TYR A  25;ALA A  94","None","1.05A","4e1gA-1b88A:undetectable","4e1gA-1b88A:10.49"],["4E1G_B_LNLB701_1","PROSTAGLANDIN G\/H SYNTHASE 2","1b88","T CELL RECEPTOR V-ALPHA DOMAIN","Mus musculus",5,"PHE A  66;ILE A  50;PHE A  33;TYR A  25;ALA A  94","None","1.04A","4e1gB-1b88A:undetectable","4e1gB-1b88A:10.49"]]