SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1b8k PROTEIN
(NEUROTROPHIN-3)
(Homo
sapiens) 		4 / 6 VAL A  97
GLY A  98
LEU A  89
GLU A  40
 None
 0.97A 1fduD-1b8kA:
undetectable		 1fduD-1b8kA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1b8k PROTEIN
(NEUROTROPHIN-3)
(Homo
sapiens) 		3 / 3 ARG A 100
ARG A  31
ILE A  28
 None
 0.76A 1uobA-1b8kA:
0.0		 1uobA-1b8kA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1b8k PROTEIN
(NEUROTROPHIN-3)
(Homo
sapiens) 		4 / 5 ILE A 102
VAL A  21
LEU A  19
ASP A 105
 None
 1.17A 3wzdA-1b8kA:
undetectable		 3wzdA-1b8kA:
15.75