SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		4 / 8 TRP A 174
GLU A 209
ARG A   4
ILE A 129
 None
 1.44A 3e7gC-1b97A:
0.0
3e7gD-1b97A:
0.0		 3e7gC-1b97A:
20.05
3e7gD-1b97A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		4 / 6 ILE A 205
TYR A 219
TYR A 215
PHE A 206
 None
 1.11A 4g10A-1b97A:
undetectable		 4g10A-1b97A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		3 / 3 LYS A  79
PRO A  80
SER A  81
 None
 0.32A 4k50I-1b97A:
0.0		 4k50I-1b97A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OAJ_E_TKTE601_1
()		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		4 / 8 TRP A 216
TYR A 230
TYR A 110
ARG A 115
 None
 1.48A 5oajD-1b97A:
0.0
5oajE-1b97A:
0.0		 5oajD-1b97A:
20.77
5oajE-1b97A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		5 / 12 THR A  96
ILE A 103
LEU A  33
PHE A 105
PHE A  44
 None
 1.30A 6a93A-1b97A:
undetectable		 6a93A-1b97A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		4 / 6 ASP A  90
ASN A 188
SER A 112
PHE A 125
 None
 1.15A 6ekuA-1b97A:
0.0		 6ekuA-1b97A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1b97 RESTRICTION
ENDONUCLEASE ECORV
(Escherichia
coli) 		5 / 9 LEU A  40
SER A  41
PHE A  44
VAL A 166
ASN A  15
 None
 1.32A 6ftpA-1b97A:
0.0
6ftpB-1b97A:
undetectable		 6ftpA-1b97A:
14.48
6ftpB-1b97A:
11.61