SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_B_CHDB2503_0 (FERROCHELATASE)	1b9g	PROTEIN (GROWTH FACTOR IGF-1) (Homo sapiens)	4 / 4	LEU A 41 PRO A 2 LEU A 44 ARG A 21	None	1.34A	1hrkB-1b9gA: undetectable	1hrkB-1b9gA: 10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_B_CHDB1604_0 (FERROCHELATASE)	1b9g	PROTEIN (GROWTH FACTOR IGF-1) (Homo sapiens)	4 / 4	LEU A 41 PRO A 2 LEU A 44 ARG A 21	None	1.34A	2hrcB-1b9gA: undetectable	2hrcB-1b9gA: 10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNJ_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	1b9g	PROTEIN (GROWTH FACTOR IGF-1) (Homo sapiens)	4 / 4	LEU A 41 PRO A 2 LEU A 44 ARG A 21	None	1.33A	2pnjB-1b9gA: undetectable	2pnjB-1b9gA: 10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_A_CHDA3_0 (FERROCHELATASE, MITOCHONDRIAL)	1b9g	PROTEIN (GROWTH FACTOR IGF-1) (Homo sapiens)	4 / 4	LEU A 41 PRO A 2 LEU A 44 ARG A 21	None	1.17A	3hcoA-1b9gA: undetectable	3hcoA-1b9gA: 10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_0 (YAEB-LIKE PROTEIN RPA0152)	1b9g	PROTEIN (GROWTH FACTOR IGF-1) (Homo sapiens)	3 / 3	LYS A 55 ARG A 43 LYS A 27	None	1.11A	3okxA-1b9gA: undetectable	3okxA-1b9gA: 18.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HRK_B_CHDB2503_0","FERROCHELATASE","1b9g","PROTEIN (GROWTH FACTOR IGF-1)","Homo sapiens",4,"LEU A  41;PRO A   2;LEU A  44;ARG A  21","None","1.34A","1hrkB-1b9gA:undetectable","1hrkB-1b9gA:10.29"],["2HRC_B_CHDB1604_0","FERROCHELATASE","1b9g","PROTEIN (GROWTH FACTOR IGF-1)","Homo sapiens",4,"LEU A  41;PRO A   2;LEU A  44;ARG A  21","None","1.34A","2hrcB-1b9gA:undetectable","2hrcB-1b9gA:10.29"],["2PNJ_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","1b9g","PROTEIN (GROWTH FACTOR IGF-1)","Homo sapiens",4,"LEU A  41;PRO A   2;LEU A  44;ARG A  21","None","1.33A","2pnjB-1b9gA:undetectable","2pnjB-1b9gA:10.29"],["3HCO_A_CHDA3_0","FERROCHELATASE, MITOCHONDRIAL","1b9g","PROTEIN (GROWTH FACTOR IGF-1)","Homo sapiens",4,"LEU A  41;PRO A   2;LEU A  44;ARG A  21","None","1.17A","3hcoA-1b9gA:undetectable","3hcoA-1b9gA:10.29"],["3OKX_B_SAMB201_0","YAEB-LIKE PROTEIN RPA0152","1b9g","PROTEIN (GROWTH FACTOR IGF-1)","Homo sapiens",3,"LYS A  55;ARG A  43;LYS A  27","None","1.11A","3okxA-1b9gA:undetectable","3okxA-1b9gA:18.40"]]