SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1b9k PROTEIN
(ALPHA-ADAPTIN
APPENDAGE DOMAIN)
(Mus
musculus) 		4 / 7 ILE A 820
PRO A 819
GLY A 714
GLN A 782
 None
 0.97A 4g0uB-1b9kA:
undetectable		 4g0uB-1b9kA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1b9k PROTEIN
(ALPHA-ADAPTIN
APPENDAGE DOMAIN)
(Mus
musculus) 		4 / 9 PHE A 795
PHE A 730
ILE A 787
MET A 737
 None
 1.25A 4jvlA-1b9kA:
0.0		 4jvlA-1b9kA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1b9k PROTEIN
(ALPHA-ADAPTIN
APPENDAGE DOMAIN)
(Mus
musculus) 		4 / 8 THR A 810
LEU A 721
VAL A 777
GLY A 809
 None
 0.88A 4r3aA-1b9kA:
1.6		 4r3aA-1b9kA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1b9k PROTEIN
(ALPHA-ADAPTIN
APPENDAGE DOMAIN)
(Mus
musculus) 		4 / 8 GLY A 779
GLN A 748
TYR A 807
ASN A 743
 None
 0.82A 4wryA-1b9kA:
undetectable		 4wryA-1b9kA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1b9k PROTEIN
(ALPHA-ADAPTIN
APPENDAGE DOMAIN)
(Mus
musculus) 		4 / 8 GLY A 779
GLN A 748
TYR A 807
ASN A 743
 None
 0.83A 4wrzA-1b9kA:
undetectable		 4wrzA-1b9kA:
21.15