SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1b9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 1b9o PROTEIN
(ALPHA-LACTALBUMIN)
(Homo
sapiens) 		5 / 12 LEU A  52
ILE A  41
ASP A  88
ILE A  89
ASP A  37
 None
None
CA  A 124 (-3.1A)
None
None
 1.11A 3axtA-1b9oA:
undetectable		 3axtA-1b9oA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1b9o PROTEIN
(ALPHA-LACTALBUMIN)
(Homo
sapiens) 		5 / 12 THR A   4
ASP A  84
ILE A  85
THR A  86
LEU A  11
 None
 1.29A 3iv6A-1b9oA:
undetectable		 3iv6A-1b9oA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1b9o PROTEIN
(ALPHA-LACTALBUMIN)
(Homo
sapiens) 		4 / 6 TYR A  50
ILE A  41
SER A  64
SER A  63
 None
 1.16A 3pmzD-1b9oA:
0.0		 3pmzD-1b9oA:
22.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 1b9o PROTEIN
(ALPHA-LACTALBUMIN)
(Homo
sapiens) 		4 / 7 GLN A  54
TRP A  60
ILE A  95
TRP A 104
 None
 0.51A 4ii8A-1b9oA:
19.4		 4ii8A-1b9oA:
37.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 1b9o PROTEIN
(ALPHA-LACTALBUMIN)
(Homo
sapiens) 		4 / 5 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.30A 5utuH-1b9oA:
undetectable		 5utuH-1b9oA:
13.92