SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bbt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RLB_E_REAE176_1 (RETINOL BINDING PROTEIN)	1bbt	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) (Foot-and-mouth disease virus)	5 / 10	ALA 1 93 ALA 1 167 VAL 1 173 LEU 1 86 ASP 1 99	None	1.20A	1rlbE-1bbt1: 0.0	1rlbE-1bbt1: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VM1_A_TAZA504_1 (BETA-LACTAMASE SHV-1)	1bbt	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) (Foot-and-mouth disease virus)	3 / 3	ASP 1 75 TYR 1 119 GLU 1 184	None	0.85A	1vm1A-1bbt1: undetectable	1vm1A-1bbt1: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARU_A_PNXA608_1 (CHITINASE A)	1bbt	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) (Foot-and-mouth disease virus)	4 / 6	ASN 1 91 SER 1 162 ALA 1 121 HIS 1 123	None	1.34A	3aruA-1bbt1: 0.1	3aruA-1bbt1: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9C_A_ECLA451_1 (CYTOCHROME P450 164A2)	1bbt	FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1) (Foot-and-mouth disease virus)	5 / 10	ALA 1 121 LEU 1 126 LEU 1 53 ALA 1 183 VAL 1 62	None	1.19A	3r9cA-1bbt1: undetectable	3r9cA-1bbt1: 19.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RLB_E_REAE176_1","RETINOL BINDING PROTEIN","1bbt","FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)","Foot-and-mouth disease virus",5,"ALA 1  93;ALA 1 167;VAL 1 173;LEU 1  86;ASP 1  99","None","1.20A","1rlbE-1bbt1:0.0","1rlbE-1bbt1:21.24"],["1VM1_A_TAZA504_1","BETA-LACTAMASE SHV-1","1bbt","FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)","Foot-and-mouth disease virus",3,"ASP 1  75;TYR 1 119;GLU 1 184","None","0.85A","1vm1A-1bbt1:undetectable","1vm1A-1bbt1:23.42"],["3ARU_A_PNXA608_1","CHITINASE A","1bbt","FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)","Foot-and-mouth disease virus",4,"ASN 1  91;SER 1 162;ALA 1 121;HIS 1 123","None","1.34A","3aruA-1bbt1:0.1","3aruA-1bbt1:16.67"],["3R9C_A_ECLA451_1","CYTOCHROME P450 164A2","1bbt","FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1)","Foot-and-mouth disease virus",5,"ALA 1 121;LEU 1 126;LEU 1  53;ALA 1 183;VAL 1  62","None","1.19A","3r9cA-1bbt1:undetectable","3r9cA-1bbt1:19.52"]]