SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 LEU A  93
ILE A  86
THR A  90
GLN A  83
 None
None
SAH  A 287 (-3.5A)
None
 1.18A 1kglA-1bc5A:
0.0		 1kglA-1bc5A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 11 LEU A 258
PRO A 223
PHE A 224
LEU A 252
PRO A 250
 None
 1.30A 1klmA-1bc5A:
0.0		 1klmA-1bc5A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 PHE A 185
PHE A  96
PHE A  97
 None
 0.88A 2od9A-1bc5A:
undetectable		 2od9A-1bc5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 PHE A 185
PHE A  96
PHE A  97
 None
 0.88A 2qqgA-1bc5A:
undetectable		 2qqgA-1bc5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 10 THR A  94
TYR A 168
ALA A 163
ALA A 124
PHE A 208
 SAH  A 287 (-3.8A)
None
None
None
None
 1.39A 2xh9B-1bc5A:
undetectable		 2xh9B-1bc5A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.14A 2y69C-1bc5A:
0.3
2y69J-1bc5A:
0.0		 2y69C-1bc5A:
21.93
2y69J-1bc5A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.22A 2y69P-1bc5A:
undetectable
2y69W-1bc5A:
0.0		 2y69P-1bc5A:
21.93
2y69W-1bc5A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 ARG A  98
GLU A 264
TYR A 235
SER A 263
 SAH  A 287 (-3.9A)
None
None
None
 1.17A 2zt7A-1bc5A:
undetectable		 2zt7A-1bc5A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.11A 3abmC-1bc5A:
undetectable
3abmJ-1bc5A:
0.0		 3abmC-1bc5A:
21.93
3abmJ-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.21A 3abmP-1bc5A:
0.3
3abmW-1bc5A:
0.0		 3abmP-1bc5A:
21.93
3abmW-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.19A 3ag3C-1bc5A:
0.3
3ag3J-1bc5A:
0.0		 3ag3C-1bc5A:
21.93
3ag3J-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 PRO A 178
LEU A 181
ARG A 187
 None
 0.84A 3aqiA-1bc5A:
2.0		 3aqiA-1bc5A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 PRO A 178
LEU A 181
ARG A 187
 None
 0.81A 3aqiB-1bc5A:
1.4		 3aqiB-1bc5A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 4 ILE A  34
PHE A  85
ILE A  30
THR A  90
 None
None
None
SAH  A 287 (-3.5A)
 1.16A 3ia4A-1bc5A:
undetectable		 3ia4A-1bc5A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 6 LEU A  22
SER A  23
PHE A  27
ILE A  30
 None
 0.93A 3ko0B-1bc5A:
0.2		 3ko0B-1bc5A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 6 LEU A  22
SER A  23
PHE A  27
ILE A  30
 None
 0.99A 3ko0S-1bc5A:
undetectable		 3ko0S-1bc5A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 ASP A 225
GLU A 116
GLY A 115
 None
 0.61A 3w9tA-1bc5A:
0.0		 3w9tA-1bc5A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 9 SER A 132
ILE A 133
GLY A 127
ALA A 163
VAL A 206
 None
 1.08A 4r1zA-1bc5A:
undetectable		 4r1zA-1bc5A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 ALA A  88
GLU A 158
PHE A  85
LEU A  73
ARG A  29
 None
 1.20A 4retA-1bc5A:
undetectable		 4retA-1bc5A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 ALA A  88
GLU A 158
PHE A  85
LEU A  73
ARG A  29
 None
 1.19A 4retC-1bc5A:
undetectable		 4retC-1bc5A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 ILE A  86
MET A 233
ASP A 154
 None
None
SAH  A 287 (-2.8A)
 0.85A 5h2uA-1bc5A:
undetectable		 5h2uA-1bc5A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 ASP A 154
ASN A 212
PHE A 228
 SAH  A 287 (-2.8A)
SAH  A 287 (-3.8A)
None
 0.85A 5jglB-1bc5A:
11.7		 5jglB-1bc5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.17A 5wauC-1bc5A:
undetectable
5wauJ-1bc5A:
0.0		 5wauC-1bc5A:
21.93
5wauJ-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.16A 5wauc-1bc5A:
undetectable
5wauj-1bc5A:
0.0		 5wauc-1bc5A:
21.93
5wauj-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.20A 5xdqC-1bc5A:
undetectable
5xdqJ-1bc5A:
0.0		 5xdqC-1bc5A:
21.93
5xdqJ-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 PHE A 103
PHE A  97
LEU A 176
PHE A 185
 None
 1.19A 5xdqP-1bc5A:
undetectable
5xdqW-1bc5A:
0.0		 5xdqP-1bc5A:
21.93
5xdqW-1bc5A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 1bc5 CHEMOTAXIS RECEPTOR
METHYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 ASN A 231
HIS A 262
ILE A 227
HIS A 102
HIS A 101
 SAH  A 287 (-4.1A)
None
None
None
None
 1.03A 6bbsA-1bc5A:
undetectable		 6bbsA-1bc5A:
16.36