SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 324
VAL A 467
THR A 297
 None
 0.85A 2nnkA-1bcoA:
0.0		 2nnkA-1bcoA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 8 LEU A 260
ASN A 267
VAL A 295
GLY A 386
 None
 0.74A 3dcjB-1bcoA:
undetectable		 3dcjB-1bcoA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ILE A 266
PHE A 318
HIS A 375
 None
 0.71A 3h0aA-1bcoA:
undetectable		 3h0aA-1bcoA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 324
VAL A 467
THR A 297
 None
 0.76A 3k4vA-1bcoA:
0.0		 3k4vA-1bcoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 324
VAL A 467
THR A 297
 None
 0.74A 3k4vD-1bcoA:
0.0		 3k4vD-1bcoA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 324
VAL A 467
THR A 297
 None
 0.74A 3nduD-1bcoA:
0.0		 3nduD-1bcoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 324
VAL A 467
THR A 297
 None
 0.81A 3tl9A-1bcoA:
0.0		 3tl9A-1bcoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L64_A_C2FA802_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 7 SER A 510
TYR A 354
ARG A 353
VAL A 307
 None
 1.38A 4l64A-1bcoA:
1.3		 4l64A-1bcoA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 6 ASP A 405
LEU A 400
HIS A 273
THR A 289
 None
 1.15A 4paeA-1bcoA:
undetectable		 4paeA-1bcoA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 LYS A 364
ASP A 362
ARG A 315
 None
 1.04A 5jwaA-1bcoA:
0.3
5jwaH-1bcoA:
0.4		 5jwaA-1bcoA:
20.11
5jwaH-1bcoA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		5 / 12 PHE A 356
PRO A 537
TYR A 518
ALA A 514
GLY A 513
 None
 1.09A 5tzoA-1bcoA:
undetectable		 5tzoA-1bcoA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		5 / 12 PHE A 356
PRO A 537
TYR A 518
ALA A 514
GLY A 513
 None
 1.04A 5tzoC-1bcoA:
undetectable		 5tzoC-1bcoA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WP1_A_BEZA403_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1bco BACTERIOPHAGE MU
TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 4 GLY A 282
PHE A 280
ASN A 281
LYS A 512
 None
 1.30A 5wp1A-1bcoA:
0.0		 5wp1A-1bcoA:
22.34