SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bdb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 5 LEU A 255
SER A 189
LEU A 191
GLY A 185
 None
NAD  A 300 (-2.5A)
NAD  A 300 (-3.8A)
NAD  A 300 (-4.5A)
 1.04A 1a4lB-1bdbA:
undetectable		 1a4lB-1bdbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 8 PHE A 139
LEU A 127
LEU A 169
LEU A 130
 None
 0.90A 1eupA-1bdbA:
0.0		 1eupA-1bdbA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 6 ALA A 107
ILE A  89
PRO A 194
GLU A 110
 None
 1.17A 1oniB-1bdbA:
0.7
1oniC-1bdbA:
0.9		 1oniB-1bdbA:
21.99
1oniC-1bdbA:
21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		7 / 11 GLY A  12
ALA A  14
SER A  15
ASP A  36
ASP A  59
VAL A  60
ALA A  87
 NAD  A 300 (-3.3A)
NAD  A 300 ( 3.9A)
NAD  A 300 (-2.6A)
NAD  A 300 (-2.7A)
NAD  A 300 (-3.2A)
NAD  A 300 (-3.6A)
NAD  A 300 ( 3.8A)
 0.46A 1uayA-1bdbA:
27.3		 1uayA-1bdbA:
31.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		7 / 10 GLY A  12
ALA A  14
SER A  15
ASP A  36
ASP A  59
VAL A  60
ALA A  87
 NAD  A 300 (-3.3A)
NAD  A 300 ( 3.9A)
NAD  A 300 (-2.6A)
NAD  A 300 (-2.7A)
NAD  A 300 (-3.2A)
NAD  A 300 (-3.6A)
NAD  A 300 ( 3.8A)
 0.48A 1uayB-1bdbA:
27.8		 1uayB-1bdbA:
31.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 5 LEU A 165
GLY A  88
ALA A 161
ILE A 162
 None
NAD  A 300 ( 3.9A)
None
None
 0.81A 2aohB-1bdbA:
undetectable		 2aohB-1bdbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 12 GLY A  12
ASP A  36
ARG A  41
ASP A  59
ASN A  86
 NAD  A 300 (-3.3A)
NAD  A 300 (-2.7A)
NAD  A 300 (-4.0A)
NAD  A 300 (-3.2A)
NAD  A 300 (-3.4A)
 1.09A 2bm9B-1bdbA:
5.1		 2bm9B-1bdbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		6 / 12 GLY A  12
ASP A  36
ARG A  41
ASP A  59
ASN A  86
ALA A  87
 NAD  A 300 (-3.3A)
NAD  A 300 (-2.7A)
NAD  A 300 (-4.0A)
NAD  A 300 (-3.2A)
NAD  A 300 (-3.4A)
NAD  A 300 ( 3.8A)
 1.01A 2bm9E-1bdbA:
5.1		 2bm9E-1bdbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 11 LEU A 165
GLY A  88
ILE A 114
ALA A 161
ILE A 162
 None
NAD  A 300 ( 3.9A)
NAD  A 300 ( 4.3A)
None
None
 0.99A 2idwA-1bdbA:
undetectable		 2idwA-1bdbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 12 LEU A 165
GLY A  88
ILE A 114
ALA A 161
ILE A 162
 None
NAD  A 300 ( 3.9A)
NAD  A 300 ( 4.3A)
None
None
 0.97A 2nmyB-1bdbA:
undetectable		 2nmyB-1bdbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 10 LEU A 165
GLY A  88
ILE A 114
ALA A 161
ILE A 162
 None
NAD  A 300 ( 3.9A)
NAD  A 300 ( 4.3A)
None
None
 0.94A 3ekpB-1bdbA:
undetectable		 3ekpB-1bdbA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 10 LEU A 165
GLY A  88
ILE A 114
ALA A 161
ILE A 162
 None
NAD  A 300 ( 3.9A)
NAD  A 300 ( 4.3A)
None
None
 1.00A 3ekpC-1bdbA:
undetectable		 3ekpC-1bdbA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 9 LEU A 165
GLY A  88
ILE A 114
ALA A 161
ILE A 162
 None
NAD  A 300 ( 3.9A)
NAD  A 300 ( 4.3A)
None
None
 1.05A 3el0B-1bdbA:
undetectable		 3el0B-1bdbA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 8 PRO A 223
TYR A 232
VAL A 182
GLY A 183
 None
 0.91A 3em0B-1bdbA:
undetectable		 3em0B-1bdbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 5 LEU A 130
ILE A  84
PRO A  85
PHE A 139
 None
 1.17A 3s3vA-1bdbA:
0.6		 3s3vA-1bdbA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		3 / 3 ASN A 180
ALA A 244
ARG A 178
 None
 0.80A 3tj7C-1bdbA:
0.0
3tj7D-1bdbA:
0.0		 3tj7C-1bdbA:
19.78
3tj7D-1bdbA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		3 / 3 SER A 189
ASP A  36
ASP A  59
 NAD  A 300 (-2.5A)
NAD  A 300 (-2.7A)
NAD  A 300 (-3.2A)
 0.92A 4mwzA-1bdbA:
7.0		 4mwzA-1bdbA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 7 TYR A 232
ALA A  20
GLY A  16
GLY A  13
 None
None
NAD  A 300 (-3.4A)
None
 0.84A 5e26A-1bdbA:
0.0
5e26B-1bdbA:
0.0		 5e26A-1bdbA:
23.36
5e26B-1bdbA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 7 GLY A  16
GLY A  12
TYR A 232
ALA A  20
 NAD  A 300 (-3.4A)
NAD  A 300 (-3.3A)
None
None
 0.89A 5e26C-1bdbA:
0.0
5e26D-1bdbA:
0.0		 5e26C-1bdbA:
23.36
5e26D-1bdbA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		4 / 7 GLY A  16
GLY A  13
TYR A 232
ALA A  20
 NAD  A 300 (-3.4A)
None
None
None
 0.87A 5e26C-1bdbA:
0.0
5e26D-1bdbA:
0.0		 5e26C-1bdbA:
23.36
5e26D-1bdbA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		3 / 3 LYS A  37
LEU A  45
ILE A  10
 NAD  A 300 (-4.4A)
None
None
 0.74A 5kc4A-1bdbA:
0.0		 5kc4A-1bdbA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 12 LEU A  35
ILE A  10
ILE A  56
GLY A  55
LEU A  42
 None
 0.79A 5twjC-1bdbA:
undetectable		 5twjC-1bdbA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 12 ALA A  87
LYS A  37
SER A  38
ASP A  59
ARG A  61
 NAD  A 300 ( 3.8A)
NAD  A 300 (-4.4A)
None
NAD  A 300 (-3.2A)
NAD  A 300 ( 4.6A)
 1.12A 5zvgA-1bdbA:
6.4		 5zvgA-1bdbA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE
(Pseudomonas
sp.) 		5 / 12 ALA A  87
LYS A  37
SER A  38
ASP A  59
ARG A  61
 NAD  A 300 ( 3.8A)
NAD  A 300 (-4.4A)
None
NAD  A 300 (-3.2A)
NAD  A 300 ( 4.6A)
 1.16A 5zvgB-1bdbA:
6.5		 5zvgB-1bdbA:
21.35