SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bfo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		6 / 11 PHE A  62
ILE A  58
LEU A  47
LEU A  21
LEU A 106
LEU A 104
 None
 1.45A 1dtlA-1bfoA:
undetectable		 1dtlA-1bfoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		4 / 5 VAL A 132
VAL A 158
GLY A 157
TRP A 148
 None
 1.14A 2p2fA-1bfoA:
undetectable		 2p2fA-1bfoA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		3 / 3 VAL B 199
VAL B 171
SER B 169
 None
 0.63A 3n8xB-1bfoB:
0.0		 3n8xB-1bfoB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		5 / 8 ALA A  84
VAL A  83
ASP A  82
LEU A  78
LEU A  73
 None
 1.49A 3roxA-1bfoA:
undetectable		 3roxA-1bfoA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		4 / 7 THR B  87
GLY B  16
VAL B  12
PRO B  14
 None
 0.84A 4forA-1bfoB:
undetectable		 4forA-1bfoB:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		4 / 5 THR B  87
GLY B  16
VAL B  12
PRO B  14
 None
 0.81A 4grkA-1bfoB:
undetectable		 4grkA-1bfoB:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		4 / 8 THR A  74
SER A  63
THR A  72
SER A  65
 None
 0.99A 5l4eA-1bfoA:
1.0
5l4eB-1bfoA:
undetectable
5l4eC-1bfoA:
undetectable
5l4eD-1bfoA:
1.0
5l4eE-1bfoA:
undetectable		 5l4eA-1bfoA:
20.31
5l4eB-1bfoA:
20.31
5l4eC-1bfoA:
20.31
5l4eD-1bfoA:
20.31
5l4eE-1bfoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		4 / 8 PHE A 118
SER A 116
THR A 114
GLY B 147
 None
 1.01A 5v0vA-1bfoA:
undetectable		 5v0vA-1bfoA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1bfo CAMPATH-1G ANTIBODY
(Rattus
rattus) 		5 / 11 VAL B 212
THR B 210
VAL B 216
ALA B 126
VAL B 160
 None
 1.15A 6dryA-1bfoB:
undetectable		 6dryA-1bfoB:
20.91