SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1bft NUCLEAR FACTOR
NF-KAPPA-B P65
(Mus
musculus) 		4 / 6 PHE A 228
TRP A 233
GLY A 208
GLY A 209
 None
 1.01A 2qr2A-1bftA:
0.0
2qr2B-1bftA:
0.0		 2qr2A-1bftA:
18.94
2qr2B-1bftA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1bft NUCLEAR FACTOR
NF-KAPPA-B P65
(Mus
musculus) 		4 / 5 TRP A 233
GLY A 208
GLY A 209
PHE A 228
 None
 1.05A 2qr2A-1bftA:
0.0
2qr2B-1bftA:
0.0		 2qr2A-1bftA:
18.94
2qr2B-1bftA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 1bft NUCLEAR FACTOR
NF-KAPPA-B P65
(Mus
musculus) 		5 / 11 ARG A 198
GLN A 287
VAL A 268
ILE A 196
ILE A 212
 None
 1.40A 3ganA-1bftA:
undetectable		 3ganA-1bftA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 1bft NUCLEAR FACTOR
NF-KAPPA-B P65
(Mus
musculus) 		4 / 6 GLU A 225
ARG A 236
ARG A 274
ARG A 273
 None
 1.22A 5l6eA-1bftA:
undetectable
5l6eB-1bftA:
undetectable		 5l6eA-1bftA:
20.37
5l6eB-1bftA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1bft NUCLEAR FACTOR
NF-KAPPA-B P65
(Mus
musculus) 		3 / 3 VAL A 226
GLU A 225
ILE A 250
 None
 0.65A 6f7lB-1bftA:
undetectable		 6f7lB-1bftA:
13.33